Web Access Research Portal

Researcher: Nichols, DS (Dr David Nichols)

Fields of Research

Bacteriology
Analytical biochemistry
Microbiology
Plant physiology
Microbial ecology
Aquaculture
Analytical spectrometry
Pharmacology and pharmaceutical sciences
Phylogeny and comparative analysis
Pharmaceutical sciences
Industrial biotechnology
Horticultural crop protection (incl. pests, diseases and weeds)
Marine and estuarine ecology (incl. marine ichthyology)
Nephrology and urology
Medical biotechnology
Behavioural neuroscience
Separation science
Flow analysis
Biochemistry and cell biology
Medical biochemistry - lipids
Nutrition and dietetics
Health services and systems
Soil biology
Manufacturing safety and quality
Plant cell and molecular biology
Preventative health care
Nutrigenomics and personalised nutrition
Post harvest horticultural technologies (incl. transportation and storage)
Proteins and peptides
Animal nutrition
Occupational and workplace health and safety
Allergy
Theory and design of materials
Sensor technology (incl. chemical aspects)
Basic pharmacology
Clinical chemistry (incl. diagnostics)
Natural products and bioactive compounds
Fish physiology and genetics
Horticultural crop growth and development
Atmospheric composition, chemistry and processes
Crop and pasture improvement (incl. selection and breeding)
Ophthalmology
Biosecurity science and invasive species ecology
Veterinary epidemiology
Plant pathology
Sport and exercise nutrition
Medicinal and biomolecular chemistry
Pollution and contamination
Food packaging, preservation and processing
Wildlife and habitat management
Agricultural land management
Epidemiology
Crop and pasture biochemistry and physiology
Gene expression (incl. microarray and other genome-wide approaches)
Biological mathematics
Instrumental methods (excl. immunological and bioassay methods)
Characterisation of biological macromolecules
Environmentally sustainable engineering
Plant developmental and reproductive biology
Evolutionary biology
Soil sciences
Microbial genetics

Research Objectives

Expanding knowledge in the environmental sciences
Management of Antarctic and Southern Ocean environments
Food safety
Field grown vegetable crops
Clinical health
Other plant production and plant primary products
Other health
Diagnosis of human diseases and conditions
Other environmental management
Expanding knowledge in the biological sciences
Beef cattle
Biodiversity in Antarctic and Southern Ocean environments
Environmentally sustainable plant production
Aquaculture fin fish (excl. tuna)
Mental health
Expanding knowledge in the chemical sciences
Assessment and management of terrestrial ecosystems
Control of pests, diseases and exotic species in terrestrial environments
Fisheries - aquaculture
Public health (excl. specific population health)
Measurement and assessment of freshwater quality (incl. physical and chemical conditions of water)
Dairy cattle
Soils
Expanding knowledge in philosophy and religious studies
Cotton
Treatment of human diseases and conditions
Alcoholic beverages
Dairy products
Nutrition
Health protection and disaster response
Industrial crops
Coastal or estuarine biodiversity
Expanding knowledge in the health sciences
Aboriginal and Torres Strait Islander health system performance
Rural and remote area health
Rice
Hardwood plantations
Coastal and estuarine systems and management
Barley
Berry fruit (excl. kiwifruit)
Grain legumes
Marine biodiversity
Health related to ageing
Other animal production and animal primary products
Animal welfare
Assessment and management of freshwater ecosystems
Women's and maternal health
Natural hazards
Terrestrial biodiversity
Industrial chemicals and related products

Career Best Publications

Abscisic acid controlled sex before transpiration in vascular plants; Proceedings of the National Academy of Sciences
Auxin biosynthesis: are the indole-3-acetic acid and phenylacetic acid biosynthesis pathways mirror images?; Plant Physiology
Cold Adaptation in the Antarctic Archaeon, Methanococcoides burtonii, Involves Membrane Lipid Unsaturation; Journal of Bacteriology
Determination of tributyltin in marine sediment and waters by pressurised solvent extraction and liquid chromatography-tandem mass spectrometry; Analytical and Bioanalytical Chemistry
Developments with Antarctic microorganisms: culture collections, bioactivity screening, taxonomy, PUFA production and cold-adapted enzymes; Current Opinions in Biotechnology
Diversity and association of psychrophilic bacteria in Antarctic Sea ice; Applied & Environmental Microbiology
Enantioselective disposition of (R)-salmeterol and (S)-salmeterol in urine following inhaled dosing and application to doping control; Drug Testing and Analysis
Leaves, not roots or floral tissue, are the main site of rapid, external pressure-induced ABA biosynthesis in angiosperms; Journal of Experimental Botany
Polyunsaturated fatty acids in marine bacteria - a dogma rewritten; Microbiology
Real-time mass spectrometry monitoring of oak wood toasting: elucidating aroma development relevant to oak-aged wine quality; Scientific Reports

Research Publications

Aequorivita gen. nov., a member of the family Flavobacteriaceae isolated from terrestrial and marine Antarctic habitats; International Journal of Systematic and Evolutionary Microbiology
Rht18 semidwarfism in wheat Is due to increased GA 2-oxidaseA9 expression and reduced GA content; Plant Physiology
Sphingomonas alaskensis Strain AFO1, an Abundant Oligotrophic Ultramicrobacterium from the North Pacific; Applied and Environmental Microbiology
A feasibility study on monitoring total phenolic content in sparkling wine press juice fractions using a new in-line system and predictive models; Food Control
A new N-C-31/9 polyene hydrocarbon from Antarctic bacteria; F E M S Microbiology Letters
A role for the cell membrane in the survival of foodborne pathogens under lethal stress conditions; 2004 Australian Society for Microbiology National Conference
Abscisic acid controlled sex before transpiration in vascular plants; Proceedings of the National Academy of Sciences
Adventures into the world of Antarctic Actinobacteria; Australian Society for Microbiology 2005 Conference
Antarctic bacteria - A new source of omega-3 polyunsaturated fatty acids; Eighth Australian Food Microbiology Conference, 8-10 February 1995
Anthocyanins attenuate vascular and inflammatory responses to a high fat high energy meal challenge in overweight older adults: A cross-over, randomized, double-blind clinical trial; Clinical Nutrition
Application of an assay for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine for the assessment of tobacco-related harm; Journal of Pharmaceutical and Biomedical Analysis
Application of thin-layer chromatography-flame ionization detection (TLC-FID) to total lipid quantitation in mycolic-acid synthesizing Rhodococcus and Williamsia species; International Journal of Molecular Sciences
Assessment of Envi-Carb as a passive sampler binding phase for acid herbicides without pH adjustment; Chemosphere
Auxin biosynthesis: are the indole-3-acetic acid and phenylacetic acid biosynthesis pathways mirror images?; Plant Physiology
Bacterial induction of settlement and metamorphosis in marine invertebrates; 8th International Coral Reef Symposium
Bacterial induction of settlement and metamorphosis in marine invertebrates; 8th International Coral Reef Symposium
Bacterial Production of Omega-3 Fatty Acids in Marine Food Webs - A New Challenge for Microbial Ecology; Microbiology Australia, The Millennium for Microbiology
Beta2-adrenergic ligand racemic formoterol exhibits enantioselective disposition in blood and skeletal muscle of humans, and elicits myocellular protein kinase A-signalling at therapeutic inhaled doses; Drug Testing and Analysis
Biodiversity and biodiscovery of Antarctic Actinobacteria; Australian Society of Microbiology Conference
Biodiversity and ecophysiology of bacteria associated with Antarctic Sea ice; Antarctic Science
Biodiversity and Ecophysiology of sea ice bacteria; AMSA '96 10-13 July 1996
Biomarker techniques to screen for bacteria that produce polyunsaturated fatty acids; Journal of Microbiological Methods
Bioprospecting and biotechnology in Antarctica; The Antarctic: Past, Present and Future
Brain-derived neurotropic factor and cortisol levels negatively predict working memory performance in healthy males; Neurobiology of Learning and Memory
Bronchopulmonary pharmacokinetics of (R)- salbutamol and (S)-salbutamol enantiomers in pulmonary epithelial lining fluid and lung tissue of horses; British Journal of Clinical Pharmacology
Case Studies of Biotechnology Opportunities in Antarctica; Looking South - Managing Technology, Opportunities and the Global Enviroment
Chemical and Physical Properties of Lipids; Chemical and Functional Properties of Food Lipids
Citrus bioflavonoids dipeptidyl peptidase-4 inhibition compared with gliptin antidiabetic medications; Biochemical and Biophysical Research Communications
Cold Adaptation in the Antarctic Archaeon, Methanococcoides burtonii, Involves Membrane Lipid Unsaturation; Journal of Bacteriology
Colwellia demingiae sp. nov., Colwellia hornerae sp. nov., Colwellia rossensis sp. nov. and Colwellia psychrotropica sp. nov.: psychrophilic Antarctic species with the ability to synthesize docosahexaenoic acid (22 : 6 omega 3); International Journal of Systematic Bacteriology
Conversion of unstable compounds can contribute to the auxin pool during sample preparation; Plant Physiology
Cytokinins and the CRE1 receptor influence endogenous gibberellin levels in Medicago truncatula; Plant Signaling and Behavior
Determination of nicotine in cartridge-based electronic cigarettes; Analytical Letters
Determination of tributyltin in marine sediment and waters by pressurised solvent extraction and liquid chromatography-tandem mass spectrometry; Analytical and Bioanalytical Chemistry
Developments with Antarctic microorganisms: culture collections, bioactivity screening, taxonomy, PUFA production and cold-adapted enzymes; Current Opinions in Biotechnology
Developments with omega-3 polyunsaturated fatty acid oils in Australia.; Fourth International Marine Biotechnology Conference
Diversity and association of psychrophilic bacteria in Antarctic Sea ice; Applied & Environmental Microbiology
Ecology and physiology of psychrophilic bacteria from Antarctic saline lakes and sea ice
Ecology of Bacteria and Fungi in Foods - Influence of Available Water
Effect of elevated temperature on astaxanthin deposition and distribution in the fillet of Atlantic salmon (Salmo salar L.) post-smolt; 18th International Symposium on Fish Nutrition and Feeding
Effect of Temperature and Salinity Stress on Growth and Lipid Composition of Shewanella gelidimarina; Applied and Environmental Microbiology
Enantioselective bronchopulmonary pharmacokinetics of salbutamol in horses; 2016 ACVIM Forum
Enantioselective disposition of (R)-salmeterol and (S)-salmeterol in urine following inhaled dosing and application to doping control; Drug Testing and Analysis
Enantioselective disposition of (R,R)-formoterol, (S,S)-formoterol and their respective glucuronides in urine following single inhaled dosing and application to doping control; Drug Testing and Analysis
Endocannabinoid reactivity to acute stress: investigation of the relationship between salivary and plasma levels; Biological Psychology
Enrichment of Rotifers Brachionus plicatilis with Eicosapentaenoic Acid and Docosahexaenoic Acid Produced by Bacteria; Journal of World Aquaculture Society
Enrichment of the rotifer Brachionus plicatilis fed an Antarctic bacterium containing polyunsaturated fatty acids; Aquaculture
Evidence that auxin is required for normal seed size and starch synthesis in pea; New Phytologist
Factors influencing the quality of Myrmecia pilosula (Jack Jumper) ant venom for use in in vitro and in vivo diagnosis of allergen sensitization and in allergen immunotherapy; Clinical and Experimental Allergy
Fatty acid adaptation in an Antarctic bacterium - Changes in primer utilization; Microbiology
First Words: Guest Editorial; Microbiology Australia
From non-targeted metabolomics to quantitative analysis of uremic compounds in chronic kidney disease; The Australian & New Zealand Metabolomics Conference (ANZMET)
Genetic techniques: PCR, NASBA, hybridisation and microarrays; Detecting Pathogens in Food
Heterogeneous astaxanthin distribution in the fillet of Atlantic salmon post-smolt at elevated temperature is not affected by dietary fatty acid composition, metabolic conversion of astaxanthin to idoxanthin, or oxidative stress; Aquaculture
Improved Detection of Polyunsaturated Fatty Acids as Phenacyl Esters by HPLC-MS-MS; IVth International Symposium on the Interface between Analytical Chemistry and Microbiology
Improved detection of polyunsaturated fatty acids as phenacyl esters using liquid chromatography-ion trap mass spectrometry; Journal of Microbiological Methods
Leaves, not roots or floral tissue, are the main site of rapid, external pressure-induced ABA biosynthesis in angiosperms; Journal of Experimental Botany
Less is More: The Influence of Nitrogen Fertiliser Application on Anthocyanins in Sweet Cherries; 43rd Annual Scientific Meeting
Linking auxin with photosynthetic rate via leaf venation; Plant Physiology
Lipids of the tail gland, body and muzzle fur of the red fox, Vulpes Vulpes; Lipids
Marine microheterotrophs as alternative sources of polyunsaturated fatt acids in aquaculture feeds; Marine biopress engineering
Marine microheterotrophs as alternative sources of polyunsaturated fatty acdis in aquaculture feeds; Marine Bioprocess Engineering International Symposium
Marine microheterotrophs as alternative sources of polyunsaturated fatty acids in aquaculture feeds; Invited symposium lecture at Australian Society of Microbiology Annual Scientific Meeting
Marine Psychrophilic Bacteria from Antarctic Sea Ice -Diversity and Unique Lipid Compositions; 5th United Kingdom Extremeophile Network meeting
Marine Psychrophilic Bacteria from Antarctic Sea Ice -Diversity and Unique Lipid Compositions; 5th United Kingdom Extremeophile Network meeting
Metabolomes of potato root exudates: compounds that stimulate resting spore germination of the soil-borne pathogen Spongospora subterranea; Journal of Agricultural and Food Chemistry
Microbial Ecology of Bacteria and Fungi - Influence of Temperature
Novel bacteria as alternate sources of polyunsaturated fatty acids for use in acquaculture and other industries; Marine Microorganisms for Industry Conference
Novel bacteria as alternate sources of polyunsaturated fatty acids in aquaculture; 6th International Tasmanian Aquaculture Exchange
Novel members of the family Flavobacteriaceae from Antarctic maritime habitats including Subsaximicrobium wynnwilliamsii gen. nov., sp. nov., Subsaximicrobium saxinquilinus sp. nov., Lacinutrix copepodicola gen. nov., sp. nov., and novel species of the genera Bizionia, Gelidibacter and Gillisia; International Journal of Systematic & Evolutionary Microbiology
Optimisation of sporosori purification and protein extraction techniques for the biotrophic protozoan plant pathogen Spongospora subterranea; Molecules
Physicochemical Parameters for Growth of the Sea Ice Bacteria Glaciecola punicea ACAM 611T and Gelidibacter sp. Strain IC158; Applied and Environmental Microbiology
Physiochemistry of blackberries (Rubus L. subgenus Rubus Watson) affected by red drupelet reversion; Postharvest Biology and Technology
Physiology of Psychrophilic Bacteria from Antarctic Sea Ice
Phytosterol supplements do not inhibit dipeptidyl peptidase-4; Diabetes & Metabolic Syndrome: clinical research & reviews
Pigment depletion in Atlantic salmon (Salmo salar) starved at high temperature: effect of dietary carotenoid type and vitamin E level; 17th International Symposium on Feeding and Nutrition of Fish
Pigment-depletion in Atlantic salmon (Salmo salar) post-smolt starved at elevated temperature is not influenced by dietary carotenoid type and increasing α-tocopherol level; Food Chemistry
Polyunsaturated fatty acids and a novel C31:9 polyene, from sea ice microbial communities; Division of Environmental Chemsitry, 212 th ACS National Meeting
Polyunsaturated fatty acids from Antarctic sea ice microalgae and bacteria; 13th Conference of the Australasian Society for Phycology and Aquatic Botany
Polyunsaturated fatty acids from sea ice algae and bacteria; Australasian Society for Phycology and Aquatic Botany
Polyunsaturated fatty acids from sea ice algae and bacteria; Australasian Society for Phycology and Aquatic Botany
Polyunsaturated fatty acids from sea ice microbial communities; Pacific Oils 2000
Polyunsaturated fatty acids from Sea Ice Microbiota; Australian Organic Geochemistry Conference 2-4 October 1996
Polyunsaturated fatty acids from sea-ice microbial communities; Third International Symposium on the Interface between Analytical Chemistry and Microbiology: Analytical Chemistry in Environmental Microbiology, March 12-15, 1995
Polyunsaturated fatty acids from sea-ice microbiota; Australian Marine Science Association, July 3-6, 1995
Polyunsaturated fatty acids in marine bacteria - a dogma rewritten; Microbiology
Polyunsaturated fatty acids in the psychrophilic bacterium Shewanella gelidimarina ACAM 456(T): molecular species analysis of major phospholipids and biosynthesis of eicosapentaenoic acid; Biochimica et Biophysica Acta - Lipids & Lipid Metabolism
Potato root exudates stimulate zoospore release of Spongospora subterranea; 8th Australasian Soilborne Diseases Symposium 2014
Potato root exudation and release of Spongospora subterranea resting spore germination stimulants are affected by plant and environmental conditions; Journal of Phytopathology
Principles of Lipid Analysis; Chemical and Functional Properties of Food Lipids
Principles of lipid analysis; Chemical and Functional Properties of Food Lipids
Production of eicosapentaenoic and arachidonic acids by an Antarctic bacterium-response to growth temperature; FEMS Microbiology Letters
Production of lactic and acetic acids by Bacillus sp. ZM20 and Bacillus cereus following exposure to zinc oxide: A possible mechanism for Zn solubilization; Rhizosphere
Prokaryotes and the input of polyunsaturated fatty acids to the marine food web
Proteomic analysis of Lactobacillus casei GCRL163 cell-free extracts reveals a SecB homolog and other biomarkers of prolonged heat stress; PLoS One
Psychrobacter glacincola sp. nov., a halotolerant, psychrophilic bacterium isolated from Antarctic sea ice; Sytematic and Applied Microbiology
Psychroflexus torquis gen. nov., sp. nov., a psychrophilic species from Antarctic sea ice, and reclassification of Flavobacterium gondwanense (Dobson et al. 1993) as Psychroflexus gondwanense gen. nov., comb. nov; Microbiology
Quantitative Microbiology: A Basis for Food Safety; Emerging Infectious Diseases
Real-time mass spectrometry monitoring of oak wood toasting: elucidating aroma development relevant to oak-aged wine quality; Scientific Reports
Reproducibility of saliva progesterone measured by immunoassay compared to liquid chromatography mass spectrometry; Analytical Biochemistry
Salmeterol undergoes enantioselective bronchopulmonary distribution with receptor localisation a likely determinant of duration of action; Journal of Pharmaceutical and Biomedical Analysis
Scent Chemicals of the Tail Gland of the Red Fox, Vulpes vulpes; Chemical Senses
Sea Ice Microbial Communities - A Unique Environment for Bacterial Production of Polyunsaturated Fatty Acids; IVth International Symposium on the Interface between Analytical Chemistry and Microbiology
Selection of SPE cartridge for automated solid-phase extraction of pesticides from water followed by liquid chromatography-tamdem mass spectrometry; Analytical and Bioanalytical Chemistry
Shewanella gelidimarina sp. nov. and Shewanella frigidimarina sp. nov., novel Antarctic species with the ability to produce eicosapentaenoic acid (20:5 omega 3) and grow anaerobically by dissimilatory Fe(III) reduction; International Journal of Systematic Bacteriology
Simultaneous quantification of endocannabinoids, oleoylethanolamide and steroid hormones in human plasma and saliva; Journal of Chromatography. B
Speciation of polyunsaturated fatty acids in the phospholipids of an Antarctic bacterium by fast atom bombardment tandem mass spectrometry; Australian and New Zealand Society for Mass Spectrometry
Strategies for Identifying New Antimicrobial Targets; Microbiology Australia
Suberin deposition in potato periderm: a novel resistance mechanism against tuber greening; New Phytologist
Suberin deposition in potato periderm: a novel resistance mechanism against tuber greening; New Phytologist
The Australian Collection of Antarctic Microorganisms (ACAM): an increasing demand for a new resource; Chemistry in Australia
The Growth of Prokaryotes in Antarctic Sea Ice: Implications for Ancient Ice Communities; Life in Ancient Ice
The nomenclature and structure of lipids; Chemical and Functional Properties of Food Lipids
The Nomenclature, Structure, and Properties of Food Lipids; Chemical and Functional Properties of Food Lipids
The Physiology of Psychrophilic Bacteria from Antarctic Sea Ice
The role of temperature and maternal ration in embryo survival: using the dumpling squid Euprymna tasmanica as a model; Journal of Experimental Marine Biology and Ecology
Triacylglycerol estolides, a new class of mammalian lipids, in the paracloacal gland of the brushtail possum (Trichosurus vulpecula); Lipids
Tryptophan metabolism in chronic kidney disease is related to the inflammation marker neopterin and to neuropsychological measures; ANZSN 51st Annual Scientific Meeting 2015
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study; BMC Nephrology
Unsaturated diether lipids in the psychrotrophic archaeon Halorubrum lacusprofundi; Systematic and Applied Microbiology
Variation of Branched-Chain Fatty Acids Marks the Normal Physiological Range for Growth in Listeria monocytogenes; Applied and Environmental Microbiology
Waterlogging tolerance in barley is associated with faster aerenchyma formation in adventitious roots; Plant and Soil

Research Projects

Biodiversity and ecophysiology of Antarctic sea-ice bacteria.; Antarctic Science Advisory Committee (ASAC)
Collaboration to build laboratory capacity within Tasmania for measurement of iodine in biological samples; University of Tasmania (UTAS)
Conversion of Branched-Chain Amino Acids to Fatty Acids: Understanding the Mechanism of Cold Tolerance in Foodborne Bacilli for Future Antimicrobials; University of Tasmania (UTAS)
Developing feasible in situ control of mange disease in wombats; Australian Research Council (ARC)
Development of Mutants from Antarctic Bacteria that produce polyunsaturated fatty acid; Australian Research Council (ARC)
Enantioselective pharmacokinetics of formoterol and application to doping control; World Anti-Doping Agency (WADA)
Field testing the reliability and cost-effectiveness of a novel locally developed assay for determining urine iodine concentration in urine samples; Royal Hobart Hospital Research Foundation (RHHRF)
Genetics of Polyunsaturated Fatty Acids in Prokaryotes; Australian Research Council (ARC)
Investigating enantioselectivity of terbutaline and the application to doping control; World Anti-Doping Agency (WADA)
Manipulating plant root exudation for soil-borne disease control; Australian Research Council (ARC)
Perturbations in Membrane Composition Define the Normal Physiological Range for Growth of Bacteria; Australian Research Council (ARC)
Polyunsaturated Fatty Acid Enzymes From Antarctic Bacteria; Australian Research Council (ARC)
Safeguarding The Young and Elderly - Design of an Anti-Listeria Biocide for Food Processing Environments; University of Tasmania (UTAS)
Stasis and Inactivation of Bacterial Pathogens on Meat and Meat Products; Meat and Livestock Australia (MLA)
The Characterisation of Actinobacteria Biodiversity from Tasmanian Cave Microhabitats; Environment Australia (EA)
The Characterisation of Actinobacteria Biodiversity from Tasmanian Cave Microhabitats; Department of Environment and Energy (Cwth) (DoEE)
The Ecophysiology of Psychrophilic Bacteria from Antarctic Sea-Ice.; Australian Research Council (ARC)
Unique plant hormone responses- the key to nitrogen-fixing nodules; Australian Research Council (ARC)
A pilot study to test an asbestos risk ratings tool adapted from the Health and Safety Executive (HSE) UK and assessment of alternative

Research Candidate Supervision

Biodiscovery and Biodiversity of Antarctic Bacteria
Fermentation Studies on Biofuel Production
Microbial Diversity in Tasmanian Caves
Microbial ecology of foods
Molecular genetics of polyunsaturated fatty acid biosynthesis in marine bacteria