Web Access Research Portal

Researcher: van der Mei, IAF (Associate Professor Ingrid van der Mei)

Fields of Research

Epidemiology
Central Nervous System
Neurology and Neuromuscular Diseases
Health, Clinical and Counselling Psychology
Preventive Medicine
Rheumatology and Arthritis
Rehabilitation and Therapy (excl. Physiotherapy)
Health Economics
Health Information Systems (incl. Surveillance)
Genetics
Health Promotion
Neurogenetics
Medical Genetics (excl. Cancer Genetics)
Autonomic Nervous System
Primary Health Care
Paediatrics and Reproductive Medicine
Immunogenetics (incl. Genetic Immunology)
Computer Perception, Memory and Attention
Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
Public Health and Health Services
Pathology
Anaesthesiology
Genomics
Cellular Immunology
Population, Ecological and Evolutionary Genetics
Complementary and Alternative Medicine
Neurosciences
Clinical Sciences
Cell and Nuclear Division
Autoimmunity

Research Objectives

Nervous System and Disorders
Preventive Medicine
Immune System and Allergy
Skeletal System and Disorders (incl. Arthritis)
Health
Behaviour and Health
Disease Distribution and Transmission (incl. Surveillance and Response)
Environmental Health
Specific Population Health (excl. Indigenous Health)
Inherited Diseases (incl. Gene Therapy)
Women's Health
Public Health (excl. Specific Population Health)
Infectious Diseases
Health Education and Promotion
Expanding Knowledge in the Medical and Health Sciences
Blood Disorders
Clinical Health (Organs, Diseases and Abnormal Conditions)
Expanding Knowledge in the Biological Sciences
Cardiovascular System and Diseases
Disability and Functional Capacity
Health Status (e.g. Indicators of Well-Being)
Injury Control
Evaluation of Health Outcomes
Allied Health Therapies (excl. Mental Health Services)
Social Structure and Health

Career Best Publications

An adverse lipid profile is associated with disability and progression in disability, in people with MS; Multiple Sclerosis Journal
Exposure to infant siblings during early life and risk of multiple sclerosis; Journal of the American Medical Association
Higher 25-hydroxyvitamin D Is Associated with Lower Relapse Risk in Multiple Sclerosis; Annals of Neurology
Human Leukocyte Antigen-DR15, Low Infant Sibling Exposure and Multiple Sclerosis: Gene-Environment Interaction; Annals of Neurology
Individual and Joint Action of Environmental Factors and Risk of MS
Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study; British Medical Journal
Regional variation in multiple sclerosis prevalence in Australia and its association with ambient ultraviolet radiation; Neuroepidemiology
Sun exposure and vitamin D are independent risk factors for CNS demyelination; Neurology

Research Publications

Varicella zoster virus quantitation in blood from symptomatic and asymptomatic individuals; Journal of Medical Virology
A novel approach for prediction of vitamin D status using support vector regression; PLoS One
A potentiation of the adverse effect of human leukocyte antigen-DR15 on the risk of multiple sclerosis by low infant sibling exposure: a population based case-control study; 13th Annnual Meeting of the Amer-Comm-for-Treatment-and-Res-in-Multiple-Sclerosis
A profile of the Multiple Sclerosis Longitudinal Study: Evaluating environmental, behavioural and genetic predictors of clinical outcomes in multiple sclerosis; Australasian Epidemiologist
Adherence to MRI protocol consensus guidelines in multiple sclerosis: An Australian multi-centre study; Journal of Medical Imaging and Radiation Oncology
Adherence to the immunomodulatory drugs for multiple sclerosis: contrasting factors affect stopping drug and missing doses; Pharmacoepidemiology and Drug Safety
Adverse lipid profile is not associated with relapse risk in MS: Results from an observational cohort study; Journal of the Neurological Sciences
An adverse lipid profile and increased levels of adiposity significantly predict clinical course after a first demyelinating event; Journal of Neurology, Neurosurgery and Psychiatry
An adverse lipid profile is associated with disability and progression in disability, in people with MS; Multiple Sclerosis Journal
Analytical bias in the measurement of serum 25-hydroxyvitamin D concentrations impairs assessment of vitamin D Status in clinical and research settings; PL o S One
Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis; Multiple sclerosis journal
Anxiety, depression and fatigue at 5-year review following CNS demyelination; Acta Neurologica Scandinavica
Apolipoprotein E4 genotype does not influence multiple sclerosis phenotype, severity, cognition or brain atrophy in a large Australian cohort; 13th Annnual Meeting of the Amer-Comm-for-Treatment-and-Res-in-Multiple-Sclerosis
Apolipoprotein genotype does not influence MS severity, cognition, or brain atrophy; Neurology
Assessing interactions between HLA-DRB1*15 and infectious mononucleosis on the risk of multiple sclerosis; Multiple Sclerosis
Association between exposure to farm animals and pets and risk of Multiple Sclerosis; Multiple Sclerosis and Related Disorders
Association between multiple sclerosis risk-associated SNPs and relapse and disability - a prospective cohort study; Multiple Sclerosis
Associations between Silicone Skin Cast Score, Cumulative Sun Exposure, and Other Factors in the Ausimmune Study: A Multicenter Australian Study ; Cancer Epidemiology, Biomarkers and Prevention
Asthma onset prior to multiple sclerosis and the contribution of sibling exposure in early life; Clinical and Experimental Immunology
Birth order, infection in early life, and multiple sclerosis; The Lancet Neurology
Cessation of exclusive breastfeeding: Australian Cross-Sectional Survey; International conference: Nutrition and Nurture in Infancy and Childhood
Challenges, lessons and new ways of communicating epidemiology; Australasian Epidemiologist
Closing the gap: Longitudinal changes in employment for Australians with multiple sclerosis; Multiple Sclerosis Journal
Combined effects of smoking, anti-EBNA antibodies, and HLA-DRB1*1501 on multiple sclerosis risk; Neurology
Complementary and alternative treatments of multiple sclerosis: a review of the evidence from 2001 to 2016; Journal of Neurology, Neurosurgery and Psychiatry
Contact dermatitis in alstroemeria workers; Occupational Medicine
CTLA-4 and multiple sclerosis: The A49G single nucleotide polymorphism shows no association with multiple sclerosis in a Southern Australian population; Journal of Neuroimmunology
CU3 Life Expectancy, Quality-Adjusted Life Years, and Total Lifetime Costs for Australian People with Multiple Sclerosis; Value in Health
Cumulative risks and cessation of exclusive breast feeding: Australian cross-sectional survey; Archives of Disease in Childhood
Current and past Epstein-Barr virus infection in risk of initial CNS demyelination; Neurology
Early-life hygiene-related factors affect risk of central nervous system demyelination and asthma differentially; Clinical and Experimental Immunology
EBV & HHV6 reactivation is infrequent and not associated with MS clinical course; Acta Neurologica Scandinavica
Epstein Barr viral infection and onset of central nervous system demyelination; 15th Annual Meeting of the Americas-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis
Exposure to infant siblings during early life and risk of multiple sclerosis; Journal of the American Medical Association
Exposure to infant siblings during early life and risk of multiple sclerosis: reply to Ruprecht and Peron; Journal of the American Medical Association
Frequency of comorbidities and their association with clinical disability and relapse in Multiple Sclerosis; Neuroepidemiology
Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis; American Journal of Human Genetics
Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis; Multiple Sclerosis Journal
Genetic variation in PBMC-produced IFN-γ and TNF-α associations with relapse in multiple sclerosis; Journal of The Neurological Sciences
Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis; Journal of Neurology, Neurosurgery and Psychiatry
Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognition ; Multiple Sclerosis
Higher 25-hydroxyvitamin D Is Associated with Lower Relapse Risk in Multiple Sclerosis; Annals of Neurology
Higher intake of omega-3 polyunsaturated fatty acids is associated with a decreased risk of a first clinical diagnosis of central nervous system demyelination: Results from the Ausimmune Study; Multiple Sclerosis
Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis; Journal of Neurology, Neurosurgery and Psychiatry
Higher levels of reported sun exposure, and not vitamin D status, are associated with less depressive symptoms and fatigue in multiple sclerosis; Acta Neurologica Scandinavica
How to safely get your daily vitamin D dose
How to safely get your daily vitamin D dose. Detailed information for the Tasmanian population
Human Leukocyte Antigen-DR15, Low Infant Sibling Exposure and Multiple Sclerosis: Gene-Environment Interaction; Annals of Neurology
Individual and Joint Action of Environmental Factors and Risk of MS
Information on Vitamin D levels for People with Multiple Sclerosis
Information Sheet
Interferon-β and serum 25-hydroxyvitamin D interact to modulate relapse risk in MS; Neurology
Investigating the patterns and determinants of seasonal variation in vitamin D status in Australian adults: the Seasonal D Cohort Study; BMC Public Health
Investigation of the role of pregnancy and exposure to biological children in the onset of central nervous system demyelination; 15th Annual Meeting of the Americas-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis
Is your association real or just reverse causality? Some examples from analyses of multiple sclerosis clinical course and tools to assess it; Australasian Epidemiologist
Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis; Journal of Neurology, Neurosurgery and Psychiatry
Latitudinal variation in incidence and type of first central nervous system demyelinating events; Multiple Sclerosis
Latitudinal variation in incidence of first demyclinating events: descriptive analyses of case participants in the Ausimmune Study; 13th Annnual Meeting of the Amer-Comm-for-Treatment-and-Res-in-Multiple-Sclerosis
Lipids in multiple sclerosis: adverse lipid profiles, disability and disease progression; Clinical Lipidology
Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye ; Virology Journal
Measuring exposure to solar ultraviolet radiation using a dosimetric technique: understanding participant compliance issues; Photochemistry and Photobiology
Melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis; Neurology
Meta-analyses to investigate gene-environment interactions in neuroepidemiology; Neuroepidemiology
Midsagittal corpus callosum area and conversion to multiple sclerosis after clinically isolated syndrome: A multicentre Australian cohort study; Journal of Medical Imaging and Radiation Oncology
Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry; Journal of Photochemistry and Photobiology, B: Biology
Modulating effects of WT1 on interferon-β-vitamin D association in MS; Acta Neurologica Scandinavica
Monthly ambient sunlight, infections and relapse rates in multiple sclerosis; Neuroepidemiology
Monthly ambient sunlight, vitamin D, infections and relapse rates in multiple sclerosis; 13th Annnual Meeting of the Amer-Comm-for-Treatment-and-Res-in-Multiple-Sclerosis
MS Environmental Study
Multiple Quantitative Trait Loci for Anti-EBNA-1 IgG Titres are Associated with Risk of Multiple Sclerosis
Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies; Neurology: Genetics
Multiple Sclerosis Susceptibility-Associated SNPs Do Not Influence Disease Severity Measures in a Cohort of Australian MS Patients; P L o S One
Multiple Sclerosis: a haplotype association study; Novartis Foundations Symposium
Novel modulating effects of PKC family genes on the relationship between serum vitamin D and relapse in multiple sclerosis; Journal of Neurology, Neurosurgery and Psychiatry
Observational analytic studies in multiple sclerosis: controlling bias through study design and conduct. The Australian Multicentre Study of Environment and Immune Function; Multiple Sclerosis
Occupational Exposure and Risk of Central Nervous System Demyelination; American Journal of Epidemiology
Offspring number, pregnancy, and risk of a first clinical demyelinating event: The AusImmune Study; Neurology
Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction ; Multiple Sclerosis
Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study; British Medical Journal
Past sun exposure, skin phenotype and risk of multiple sclerosis: a case-control study; 15th Conference of the International Society for Environmental Epidemiology 2003
Past sun exposure, skin phenotype and risk of multiple sclerosis: a case-control study; Epidemiology
PND13 Assessing Health-State Utility Values in Australian People with Multiple Sclerosis; Value in Health
Population attributable fractions and joint effects of key risk factors for multiple sclerosis; Multiple Sclerosis Journal
Predictors of Beagley-Gibson skin cast grade in older adults; Skin Research and Technology
Prevalence and concurrence of anxiety, depression and fatigue over time in multiple sclerosis; Multiple Sclerosis
Public Forum: Dispelling the myths of MS
Regional variation in multiple sclerosis prevalence in Australia and its association with ambient ultraviolet radiation; Neuroepidemiology
Reply: Vitamin D supplementation; Australian Family Physician
Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study; Journal of Neurology, Neurosurgery and Psychiatry
Role of vitamin D in multiple sclerosis: implications for disease management
Self-Reported changes in sun-protection behaviors at different latitudes in Australia; Photochemistry and Photobiology
Smoking as an independent risk factor for multiple sclerosis: considering possible combined effects with the human leukocyte antigen DR15 genotype and anti-EBNA antibody titers; 13th Annnual Meeting of the Amer-Comm-for-Treatment-and-Res-in-Multiple-Sclerosis
Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis ; Journal of Neurology: Official Journal of The European Neurological Society
Stimulated PBMC-produced IFN-γ and TNF-α are associated with altered relapse risk in multiple sclerosis: Results from a prospective cohort study; Journal of Neurology, Neurosurgery and Psychiatry
Stressful life events and the risk of initial central nervous system demyelination; Multiple Sclerosis Journal
Sun exposure and vitamin D are independent risk factors for CNS demyelination; Neurology
Sun exposure over a lifetime in Australian adults from latitudinally diverse regions; Photochemistry and Photobiology
Synergetic and antagonistic effects of combined calcitriol and interferon-β treatment on cytokine production by stimulated PBMCs; Journal of Neuroimmunology
The AusD Study: A Population-based Study of the Determinants of Serum 25-Hydroxyvitamin D Concentration Across a Broad Latitude Range; American Journal of Epidemiology
The co-occurrence of multiple sclerosis and type 1 diabetes: Shared aetiologic features and clinical implication for MS aetiology; Journal of the Neurological Sciences
The contributions of solar ultraviolet radiation exposure and other determinants to serum 25-hydroxyvitamin D concentrations in Australian adults: The AusD study; American Journal of Epidemiology
The effect of season on cytokine expression in multiple sclerosis and healthy subjects; Journal of Neuroimmunology
The genetics of multiple sclerosis
The High Prevalence of Vitamin D Insufficiency across Australian Populations Is Only Partly Explained by Season and Latitude; Environmental Health Perspectives
The HLA-DR2 genotype does not affect MS severity, cognition or brain atrophy; 25th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis
The impact of multiple sclerosis severity on health state utility values: Evidence from Australia; Multiple Sclerosis Journal
The physical anthropometry, lifestyle habits and blood pressure of people presenting with a first clinical demyelinating event compared to controls: the Ausimmune study; Multiple Sclerosis Journal
The potential role of epigenetic modifications in the heritability of multiple sclerosis; Multiple Sclerosis Journal
The relationship between ambient ultraviolet radiation (UVR) and objectively measured personal UVR exposure dose is modified by season and latitude; Photochemical & Photobiological Sciences
The role of epidemiology in MS research: Past successes, current challenges and future potential; Multiple Sclerosis Journal
The role of latitude, ultraviolet radiation exposure and vitamin D in childhood asthma and hayfever: an Australian multicenter study ; Pediatric Allergy and Immunology
The Role of Sun Exposure in Multiple Sclerosis
The Tasmanian Multiple Sclerosis Program; Australasian Epidemiologist
The Varied Mechanisms of Vitamin D in the Onset and Clinical Course of MS: Potential Roles in Modulating Other Etiological Pathways
Trends in the epidemiology of multiple sclerosis in Greater Hobart, Tasmania: 1951 to 2009; Journal of Neurology, Neurosurgery and Psychiatry
Ultraviolet radiation and autoimmune disease: insights from epidemiological research
Ultraviolet radiation and autoimmune disease: insights from epidemiological research; Toxicology
Ultraviolet radiation and autoimmune disease: insights from epidemiological research; Toxicology
Ultraviolet radiation and organ-specific auto-immune disease: insights form epidemiological research; UVR Meeting
UVR, vitamin D and three autoimmune diseases - multiple sclerosis, type 1 diabetes, rheumatoid arthritis; Photochemistry and Photobiology
Validation of linear cerebral atrophy markers in multiple sclerosis; Journal of Clinical Neuroscience
Validation of sun exposure reported annually against interim self-report and daily sun diaries; Photochemistry and Photobiology
Validity and reliability of adult recall of past sun exposure in a case-control study of multiple sclerosis; Cancer Epidemiology, Biomarkers & Prevention
Variability in vitamin D assays impairs clinical assessment of vitamin D status; Internal Medicine Journal
Variation within MBP gene predicts disease course in multiple sclerosis; Brain and Behavior
Vascular comorbidities in the onset and progression of multiple sclerosis; Journal of The Neurological Sciences
Vitamin D and multiple sclerosis; Journal of Clinical Neuroscience
Vitamin D and the musculoskeletal health of older adults; Australian Family Physician
Vitamin D deficiency in Tasmania and its treatment
Vitamin D deficiency in Tasmania: A whole of life perspective; Internal Medicine Journal
Vitamin D deficiency linked to MS and other diseases
Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia; Journal of Neurology
Vitamin D status: Multifactorial contribution of environment, genes and other factors in healthy Australian adults across a latitude gradient; Journal of Steroid Biochemistry and Molecular Biology
Vitamin D supplementation in infancy for improving bone density (protocol); The Cochrane Library
Vitamin D supplementation in infants
Waterpipe smoking associated with multiple sclerosis: A population-based incident case-control study; Multiple Sclerosis Journal
Weekend personal ultraviolet radiation exposure in four cities in Australia: Influence of temperature, humidity and ambient ultraviolet radiation; Journal of Photochemistry and Photobiology B: Biology
Weekly cholecalciferol supplementation results in significant reductions in infection risk among the vitamin D deficient: results from the CIPRIS pilot RCT; BMC Nutrition
What affects your MS? Responses to an anonymous, Internet-based epidemiological survey; Multiple Sclerosis
Who's missing out? Pharmionics and the immunomodulatory therapies for MS; 23rd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis

Research Projects

A Case Control Study to Investigate the Contribution of Sun Exposure, Family Structure and other Environmental Factors to Multiple Sclerosis in Tasmania; Multiple Sclerosis Research Australia (MSRA)
A double-blind randomised controlled trial to evaluate the efficacy of 20,000 IU/wk cholecalciferol in reducing respiratory tract infection in a cohort of healthy young adults; Royal Hobart Hospital Research Foundation (RHHRF)
Ausimmune Study; MS Society of Tasmania (MSTas)
Case-control study in Primary Progressive MS: Are the risk factors the same as for people with RRMS onset and can we identify new ones?; Multiple Sclerosis Research Australia (MSRA)
DEVA MS: DEvelopment and VAlidation of a cost effectiveness simulation model for Multiple Sclerosis and implications for health policy; Multiple Sclerosis Research Australia (MSRA)
Does treating multiple sclerosis alter long-term disease outcomes? a natural history study; Multiple Sclerosis Research Australia (MSRA)
Effect of EBV and HHV-6 latent infection or reactivation on MS activity: a prospective clinical cohort study; National Health & Medical Research Council (NHMRC)
Effect of vitamin D supplementation of the currently used dosage regime of 400 IU/d on vitamin D levels in infants; Royal Hobart Hospital Research Foundation (RHHRF)
Examining the role of blood lipids and apolipoproteins on the progression of MS in a prospective clinical cohort; Royal Hobart Hospital Research Foundation (RHHRF)
Examining the role of lipids in the progression of MS in a prospective cohort study; Multiple Sclerosis Research Australia (MSRA)
From risk factor analysis to translation: Multiple Sclerosis and vitamin D deficiency; Australian Research Council (ARC)
Gene-environment interaction in MS risk and progression: focus on ultraviolet radiation and Epstein-Barr virus pathways; National Health & Medical Research Council (NHMRC)
Identification of Genes that Influence MS Progression by Pathways that Involve UV Exposure: a Prospective Cohort Study; Ian Potter Foundation (IPF)
Minolta Spectrophotometer CM-508i; National Health & Medical Research Council (NHMRC)
Once-off population health projects; Department of Health and Human Services Tasmania (DHHS)
Prognostic factors following a first episode of central nervous system demyelination suggestive of multiple sclerosis; National Health & Medical Research Council (NHMRC)
Proposal to visit the Harvard School of Public Health in Boston USA; Ian Potter Foundation (IPF)
Quantitative assessment of solar UV exposure for vitamin D synthesis in Australian adults; National Health & Medical Research Council (NHMRC)
Rising Star; University of Tasmania (UTAS)
Study tour to Harvard School of Public Health, Boston; Multiple Sclerosis International Federation (MSIF)
The Australian Multi-Centre Study of Environment and Immune Function; National Multiple Sclerosis Society (NMSS)
The Cholecalciferol Intervention to Prevent Respiratory Infections Study (CIPRIS); The Select Foundation (SelF)
The efficacy of vitamin D supplementation in early life on bone health: Pilot of a double-blind randomized controlled trial; The Marian and EH Flack Trust (Flack)
The role of environmental and genetic factors in progression of multiple sclerosis; National Health & Medical Research Council (NHMRC)
The Role of Personal UVR Exposure on the Clinical Course of MS: A Prospective Cohort Study; Trish Multiple Sclerosis Research Foundation (TMSRF)
What predicts the progressive phase of multiple sclerosis?; National Health & Medical Research Council (NHMRC)
AMSLS Prospective DMT analysis
Australian MS Longitudinal study
Australian MS Longitudinal Study and MSBase Data Linkage program
Creating an MS Portal to achieve better outcomes for people with MS
Economic Impact of MS - 2007 cost of illness data AMSLS - PPMS sub-analysis
inforMS - a new patient-driven health care model for MS
inforMS- a new patient-driven health care model for MS
Ingrid van der Mei - Discretionary Account
A Case Control Study of Past Sun Exposure and First Demyelinating Events

Research Candidate Supervision

Determinations of MS progression
Dissecting the Genetics Architecture of Multiple Sclerosis
Genetics of Complex Diseases
Monitoring and Prevention of the Early Cessation of Breastfeeding
On the Geoepidemiology of Multiple Sclerosis and Environmental and Infectious Determinants of its Clinical Course
The effect of dietary intake and vitamin supplementation on the progression of Multiple Sclerosis- A prospective cohort study
The Influence of HLA_DRA15 on Multiple Sclerosis
The Role of Epstein-Bar Virus and Human Herpes Virus 6 on the Progression of Multiple Sclerosis
The Role of Stress in Multiple Sclerosis Onset and Progression
Vitamin D Deficiency in the General Population