Web Access Research Portal

Researcher: Dwyer, RM (Dr Renee Dwyer)

Fields of Research

Endocrinology
Cardiology (incl. Cardiovascular Diseases)
Systems Physiology
Physiology
Medical Bacteriology
Health and Community Services
Medical and Health Sciences
Public Nutrition Intervention
Animal Physiology - Biophysics
Epigenetics (incl. Genome Methylation and Epigenomics)
Cell Metabolism
Medical Biotechnology
Motor Control
Medical Biochemistry: Amino Acids and Metabolites

Research Objectives

Diabetes
Cardiovascular System and Diseases
Expanding Knowledge in the Medical and Health Sciences
Endocrine Organs and Diseases (excl. Diabetes)
Infectious Diseases
Inherited Diseases (incl. Gene Therapy)
Expanding Knowledge in the Biological Sciences
Neurodegenerative Disorders Related to Ageing
Nutrition
Human Pharmaceutical Treatments (e.g. Antibiotics)
Human Diagnostics
Clinical Health (Organs, Diseases and Abnormal Conditions)

Career Best Publications

Acute blockade by endothelin-1 of haemodynamic insulin action in rats; Diabetologia
Local nitric oxide synthase inhibition reduces skeletal muscle glucose uptake but not capillary blood flow during in situ muscle contraction in rats; Diabetes

Research Publications

A comparison of ultrasound and laser Doppler for Measuring Capillary Recruitment Using Models in vitro; ACSM Conference on Integrative Physiology of Exercise
Acute blockade by endothelin-1 of haemodynamic insulin action in rats; Diabetologia
Contrast-enhanced ultrasound measurement of microvascular perfusion relevant to nutrient and hormone delivery in skeletal muscle: A model study in vitro; Microvascular Research
Decreased microvascular vasomotion and myogenic response in rat skeletal muscle in association with acute insulin resistance; Journal of Physiology
Determination of skeletal muscle microvascular flowmotion with contrast-enhanced ultrasound; Ultrasound in Medicine and Biology
Endothelin-1 inhibits insulin action in vivo; 42nd Annual Meeting of the EASD
Flow motion in skeletal muscle is associated with increased nutritive flow and insulin action; 71st Scientific Sessions of the American Diabetes Association
Flow motion in skeletal muscle microvasculature is associated with increased nutritive flow; Australia and New Zealand Microcirculation Society Conference
Insulin and contraction increase nutritive blood flow in rat muscle in vivo: determined by microdialysis of L-[14C]glucose; Journal of Physiology
Integrating muscle cell biochemistry and whole-body physiology in humans: 31P-MRS data from the InSight trial; Scientific Reports
Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor- expression; Diabetes
Interleukin-6 increases glucose uptake but does not increase AMPK activity in L6 myotubes and perfused rat hindlimb; AMPK 2004, 3rd International Symposium on AMP-activated protein kinase
Laser Doppler flowmetry, but not contrast enhanced ultrasound, influenced by flow when measuring changes in muscle capillary recruitment - a study in vitro; Exercise, Insulin Sensitivity and Diabetes - What is new?
Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat; Journal of Applied Physiology
Local nitric oxide synthase inhibition reduces skeletal muscle glucose uptake but not capillary blood flow during in situ muscle contraction in rats; Diabetes
Muscle microvascular blood flow responses in insulin resistance and ageing; The Journal of Physiology
No effect of NOS inhibition on skeletal muscle glucose uptake during in situ hindlimb contraction in healthy and diabetic Sprague-Dawley rats; American Journal of Physiology: Regulatory, Integrative and Comparative Physiology
Obesity, Insulin Resistance, and Capillary Recruitment; Microcirculation
Regulation of microvascular flow and metabolism: An overview; Clinical and Experimental Pharmacology and Physiology
Role for the Microvasculature in Glucose Uptake in Skeletal Muscle; Glucose Uptake: Regulation, Signaling Pathways and Health Implications (Endocrinology Research and Clinical Developments)
Skeletal Muscle Microvascular-Linked Improvements in Glycemic Control From Resistance Training in Individuals With Type 2 Diabetes; Diabetes Care
The Impact of Sex and 25(OH)D Deficiency on Metabolic Function in Mice; Nutrients
The Impacts of Iron Laden Particulate Matter on NTHi Growth; Australian Society for Microbiology Annual Scientific Meeting 2017
The reproducibility of 31-phosphorous MRS measures of muscle energetics at 3 tesla in trained men; PLoS One
Use of microdialysis to assess capillary recruitment in muscle - a study in vitro; Exercise, Insulin Sensitivity and Diabetes - What is nes?

Research Projects

Cardiometabolic benefits of exercise training in type 2 diabetes independent of weight loss; University of Tasmania (UTAS)
Role of microvascular flowmotion in skeletal muscle glucose metabolism; National Health & Medical Research Council (NHMRC)

Research Candidate Supervision

The role of Flowmotion in Regulating Basal and Insulin-mediated Skeletal Glucose Uptake