Web Access Research Portal

Researcher: Magnussen, CG (Dr Costan Magnussen)

Fields of Research

Epidemiology
Cardiology (incl. Cardiovascular Diseases)
Preventive Medicine
Public Health and Health Services
Public Nutrition Intervention
Human Movement and Sports Science
Health Counselling
Neurology and Neuromuscular Diseases
Paediatrics
Endocrinology
Continuing and Community Education
Health Promotion
Aboriginal and Torres Strait Islander Health
Foetal Development and Medicine
Medical Biochemistry: Amino Acids and Metabolites
Clinical Sciences
Geriatrics and Gerontology

Research Objectives

Cardiovascular System and Diseases
Preventive Medicine
Diabetes
Health Education and Promotion
Behaviour and Health
Child Health
Public Health (excl. Specific Population Health)
Disability and Functional Capacity
Evaluation of Health Outcomes
Learner and Learning
Diagnostic Methods
Social Structure and Health
Health Status (e.g. Indicators of Well-Being)
Health Related to Ageing

Career Best Publications

A diagnosis of the Metabolic Syndrome in youth that resolves by adult life is associated with a normalization of high Carotid Intima-Media Thickness and Type 2 Diabetes Mellitus Risk: the Bogalusa heart and cardiovascular risk in Young Finns Studies; Journal of the American College of Cardiology
Adolescence risk factors are predictive of coronary artery calcification at middle age: the Cardiovascular Risk in Young Finns Study; American College of Cardiology. Journal
Arterial structure and function after recovery from the Metabolic Syndrome - The cardiovascular risk in young Finns Study ; Circulation
Childhood Adiposity, Adult Adiposity, and Cardiovascular Risk Factors; New England Journal of Medicine
Combined effects of child and adult elevated blood pressure on subclinical atherosclerosis: The International Childhood Cardiovascular Cohort Consortium; Circulation
Exposure to parental smoking in childhood is associated with increased risk of carotid atherosclerotic plaque in adulthood: the Cardiovascular Risk in Young Finns Study; Circulation
Exposure to parental smoking in childhood or adolescence is associated with increased carotid intima-media thickness in young adults: evidence from the Cardiovascular Risk in Young Finns study and the Childhood Determinants of Adult Health Study; European Heart Journal
Factors Affecting the Stability of Blood Lipid and Lipoprotein Levels From Youth to Adulthood: Evidence from the Childhood Determinants of Adult Health Study; Archives of Pediatrics and Adolescent Medicine
High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis; European Heart Journal
Ideal Cardiovascular Health in Childhood and Cardiometabolic Outcomes in Adulthood: The Cardiovascular Risk in Young Finns Study; Circulation
Influence of Age on Associations Between Childhood Risk Factors and Carotid Intima-Media Thickness in Adulthood - The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium ; Circulation
Pediatric metabolic syndrome predicts adulthood metabolic syndrome, subclinical atherosclerosis, and Type 2 diabetes mellitus but is no better than body mass index alone - the Bogalusa heart study and the cardiovascular risk in young Finns study ; Circulation
The Association of Pediatric Low- and High-Density Lipoprotein Cholesterol Dyslipidemia Classifications and Change in Dyslipidemia Status With Carotid Intima-Media Thickness in Adulthood ; American College of Cardiology. Journal
Utility of Currently Recommended Pediatric Dyslipidemia Classifications in Predicting Dyslipidemia in Adulthood; Circulation

Research Publications

A diagnosis of the Metabolic Syndrome in youth that resolves by adult life is associated with a normalization of high Carotid Intima-Media Thickness and Type 2 Diabetes Mellitus Risk: the Bogalusa heart and cardiovascular risk in Young Finns Studies; Journal of the American College of Cardiology
A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study; Atherosclerosis
Adolescence risk factors are predictive of coronary artery calcification at middle age: the Cardiovascular Risk in Young Finns Study; American College of Cardiology. Journal
Adult dyslipidemia prediction is improved by repeated measurements in childhood and young adulthood. The Cardiovascular Risk in Young Finns Study; Atherosclerosis
Apolipoprotein B, oxidized low-density lipoprotein, and LDL particle size in predicting the incidence of metabolic syndrome: the Cardiovascular Risk in Young Finns study; European Journal of Cardiovascular Prevention & Rehabilitation
Arterial structure and function after recovery from the Metabolic Syndrome - The cardiovascular risk in young Finns Study ; Circulation
Association of liver enzymes with metabolic syndrome and carotid atherosclerosis in young adults. The Cardiovascular Risk in Young Finns Study; Annals of Medicine
Association of physical activity in childhood and early adulthood with carotid artery elasticity 21 years later: the cardiovascular risk in Young Finns Study; Journal of the American Heart Association
Association of Socioeconomic Status in Childhood With Left Ventricular Structure and Diastolic Function in Adulthood: The Cardiovascular Risk in Young Finns Study; JAMA Pediatrics
Bayesian hierarchical piecewise regression models: a tool to detect trajectory divergence between groups in long-term observational studies; BMC Medical Research Methodology
Cardiovascular risk factors in 2011 and secular trends since 2007: The Cardiovascular Risk in Young Finns Study; Scandinavian Journal of Public Health
Cardiovascular risk scores in the prediction of subclinical atherosclerosis in young adults: evidence from the cardiovascular risk in a young Finns study ; European Journal of Cardiovascular Prevention & Rehabilitation
Carotid artery intima-media thickness and hypertensive heart disease: a short review; Clinical Hypertension
Carotid extra-medial thickness does not predict adverse cardiovascular outcomes in high-risk adults; Diabetes & Metabolism
Changes in daily steps and body mass index and waist to height ratio during four year follow-up in adults: Cardiovascular Risk in Young Finns Study; International Journal of Environmental Research and Public Health
Childhood 25-OH vitamin D levels and carotid intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study; Journal of Clinical Endocrinology and Metabolism
Childhood Adiposity, Adult Adiposity, and Cardiovascular Risk Factors; New England Journal of Medicine
Childhood age and associations between childhood metabolic syndrome and adult risk for metabolic syndrome, type 2 diabetes mellitus and carotid intima media thickness: The International Childhood Cardiovascular Cohort Consortium; Journal of the American Heart Association
Childhood Environmental and Genetic Predictors of Adulthood Obesity: The Cardiovascular Risk in Young Finns Study; Journal of Clinical Endocrinology and Metabolism
Childhood fitness reduces the long-term cardiometabolic risks associated with childhood obesity; International Journal of Obesity
Childhood infections, socioeconomic status, and adult cardiometabolic risk; Pediatrics (English Edition)
Childhood lifestyle and clinical determinants of adult ideal cardiovascular health. The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Princeton Follow-up Study; International Journal of Cardiology
Childhood Muscular Fitness Phenotypes and Adult Metabolic Syndrome; Medicine and Science in Sports and Exercise
Childhood Nutrition in Predicting Metabolic Syndrome in Adults: The Cardiovascular Risk in Young Finns Study; Diabetes Care
Childhood physical, environmental, and genetic predictors of Adult Hypertension: the Cardiovascular Risk in Young Finns Study; Circulation
Childhood Psychosocial Factors and Coronary Artery Calcification in Adulthood: The Cardiovascular Risk in Young Finns Study; JAMA Pediatrics
Childhood Socioeconomic Status in Predicting Metabolic Syndrome and Glucose Abnormalities in Adulthood: The Cardiovascular Risk in Young Finns Study; Diabetes Care
Cohort Profile: The International Childhood Cardiovascular Cohort (i3C) Consortium; International Journal of Epidemiology
Combined effects of child and adult elevated blood pressure on subclinical atherosclerosis: The International Childhood Cardiovascular Cohort Consortium; Circulation
Continuous and dichotomous metabolic syndrome definitions in youth predict adult type 2 diabetes and carotid artery intima media thickness: the Cardiovascular Risk in Young Finns Study; Journal of Pediatrics
Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study ; International Journal of Epidemiology
Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study; European Heart Journal - Cardiovascular Imaging
Daily steps among Finnish adults: Variation by age, sex, and socioeconomic position; Scandinavian Journal of Public Health
Decline in Physical Fitness From Childhood to Adulthood Associated With Increased Obesity and Insulin Resistance in Adults ; Diabetes Care
Determinants of serum 25(OH)D concentration in young and middle-aged adults. The Cardiovascular Risk in Young Finns Study; Annals of Medicine
Development of hypertension in overweight adolescents: a review; Adolescent Health, Medicine and Therapeutics
Does childhood nutrition influence adult cardiovascular disease risk? - Insights from the Young Finns Study; Annals of Medicine
Does youth adiposity, or change in adiposity from youth to adulthood, predict metabolically healthy obesity in adulthood?; Pediatric Obesity
Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: The Cardiovascular Risk in Young Finns Study; Atherosclerosis
East-west differences and migration in Finland: Association with cardiometabolic risk markers and IMT. The Cardiovascular Risk in Young Finns Study; Scandinavian Journal of Public Health
Effect of age, gender and cardiovascular risk factors on carotid distensibility during 6-year follow-up. The cardiovascular risk in Young Finns study; Atherosclerosis
Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns Study; Journal of Hypertension
Effectiveness of a puppet show on iodine knowledge, attitudes and behaviour of elementary students and the indirect effects on their parents and households in Ho Chi Minh City: a pilot study ; Public Health
Epidemiology of elevated blood pressure in youth and its utility for predicting adulthood outcomes: A review; World Journal of Hypertension
Evaluating the use of a portable ultrasound machine to quantify intima-media thickness and flow-mediated dilatation: Agreement between measurements from two ultrasound machines; Ultrasound in Medicine and Biology
Exposure to Parental Smoking in Childhood is Associated with High C-Reactive Protein in Adulthood: The Cardiovascular Risk in Young Finns Study; Journal of Atherosclerosis and Thrombosis
Exposure to parental smoking in childhood is associated with increased risk of carotid atherosclerotic plaque in adulthood: the Cardiovascular Risk in Young Finns Study; Circulation
Exposure to parental smoking in childhood or adolescence is associated with increased carotid intima-media thickness in young adults: evidence from the Cardiovascular Risk in Young Finns study and the Childhood Determinants of Adult Health Study; European Heart Journal
Factors Affecting the Stability of Blood Lipid and Lipoprotein Levels From Youth to Adulthood: Evidence from the Childhood Determinants of Adult Health Study; Archives of Pediatrics and Adolescent Medicine
Factors affecting tracking of blood pressure from childhood to adulthood: the Childhood Determinants of Adult Health Study; Journal of Pediatrics
Family history of premature coronary heart disease, child cardio-metabolic risk factors and left ventricular mass; Cardiology in the Young
Genotype prediction of adult Type 2 diabetes from adolescence in a multiracial population; Pediatrics
High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis; European Heart Journal
Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring; Journal of Pediatrics
Ideal Cardiovascular Health in Childhood and Cardiometabolic Outcomes in Adulthood: The Cardiovascular Risk in Young Finns Study; Circulation
Ideal cardiovascular health in childhood-Longitudinal associations with cardiac structure and function: The Special Turku Coronary Risk Factor Intervention Project (STRIP) and the Cardiovascular Risk in Young Finns Study (YFS); International Journal of Cardiology
Ideal cardiovascular health in young adult populations from the United States, Finland, and Australia and its association with cIMT: the International Childhood Cardiovascular Cohort Consortium; Journal of the American Heart Association
Impact of adiposity on cardiac structure in adult life: the childhood determinants of adult health (CDAH) study; BMC Cardiovascular Disorders
In Reply: Cleland et al Respond to 'Physical activity over the life course: whose behavior changes, when and why?'; American Journal of Epidemiology
Increased body mass index in parent-child dyads predicts the offspring risk of meeting bariatric surgery criteria; Journal of Clinical Endocrinology and Metabolism
Increasing stair usage in a professional workplace: a test of the efficacy of positive and negative message prompts to change pedestrian choices; Health Promotion Journal of Australia
Infection-related hospitalization in childhood and adult metabolic outcomes; Pediatrics
Influence of Age on Associations Between Childhood Risk Factors and Carotid Intima-Media Thickness in Adulthood - The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium ; Circulation
Insulin and BMI as predictors of adult type 2 diabetes mellitus; Pediatrics
Is passive smoking exposure in early life a risk factor for future cardiovascular disease?; Current Cardiovascular Risk Reports
Life-course risk factor levels and coronary artery calcification. The Cardiovascular Risk in Young Finns Study; International Journal of Cardiology
Lifetime measures of ideal cardiovascular health and their association with subclinical atherosclerosis: The Cardiovascular Risk in Young Finns Study; International Journal of Cardiology
Long term risk of severe retinopathy in childhood-onset type 1 diabetes: a data linkage study; Medical Journal of Australia
Longitudinal investigation of adenovirus 36 seropositivity and human obesity: The Cardiovascular Risk in Young Finns Study; International Journal of Obesity
Low vitamin D is associated with hypertension in paediatric obesity; Journal of Paediatrics and Child Health
Metabolic syndrome from adolescence to early adulthood: effect of infancy-onset dietary counseling of low saturated fat: the Special Turku Coronary Risk Factor Intervention Project (STRIP); Circulation
Muscular fitness and clustered cardiovascular disease risk in Australian youth; European Journal of Applied Physiology
Parental smoking in childhood and brachial artery flow-mediated dilatation in young adults: The Cardiovascular Risk in Young Finns Study and the Childhood Determinants of Adult Health Study; Arteriosclerosis, Thrombosis, and Vascular Biology
Parental smoking produces long-term damage to vascular function in their children
Pediatric Blood Pressure and Adult Preclinical Markers of Cardiovascular Disease; Clinical Medicine Insights: Blood Disorders
Pediatric metabolic syndrome predicts adulthood metabolic syndrome, subclinical atherosclerosis, and Type 2 diabetes mellitus but is no better than body mass index alone - the Bogalusa heart study and the cardiovascular risk in young Finns study ; Circulation
Positive psychosocial factors in childhood predicting lower risk for adult type 2 diabetes: the Cardiovascular Risk in Young Finns Study, 1980-2012; American Journal of Preventive Medicine
Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study; Circulation - Cardiovascular Genetics
Predictive associations between alternative measures of childhood adiposity and adult cardio-metabolic health ; International Journal of Obesity
Relation of total and free testosterone and sex hormone-binding globulin with cardiovascular risk factors in men aged 2445 years. The Cardiovascular Risk in Young Finns Study; Atherosclerosis
Relative contributions of adiposity in childhood and adulthood to vascular health of young adults; Atherosclerosis
Reliability and Validity of the Global Physical Activity Questionnaire in Vietnam; Journal of Physical Activity & Health
Repeated blood pressure measurements in childhood in prediction of hypertension in adulthood; Hypertension
Resting heart rate and the association of physical fitness with carotid artery stiffness; American Journal of Hypertension
Resting Heart Rate and the Association of Physical Fitness With Carotid Artery Stiffness; American Journal of Hypertension
Simplified definitions of elevated pediatric blood pressure and high adult arterial stiffness; Pediatrics (English Edition)
Socioeconomic Position and the Tracking of Physical Activity and Cardiorespiratory Fitness From Childhood to Adulthood; American Journal of Epidemiology
Socioeconomic position Is associated with carotid intima-media thickness in mid-childhood: The longitudinal study of Australian children; Journal of the American Heart Association
Socioeconomic status, cardiovascular risk factors, and subclinical atherosclerosis in young adults: The Cardiovascular Risk in Young Finns Study; Arteriosclerosis, Thrombosis, and Vascular Biology
The Association of Pediatric Low- and High-Density Lipoprotein Cholesterol Dyslipidemia Classifications and Change in Dyslipidemia Status With Carotid Intima-Media Thickness in Adulthood ; American College of Cardiology. Journal
The Association of Type 2 Diabetes Mellitus with Cerebral Gray Matter Volume Is Independent of Retinal Vascular Architecture and Retinopathy; Journal of Diabetes Research
The combined effect of common genetic risk variants on circulating lipoproteins is evident in childhood: A longitudinal analysis of the cardiovascular risk in Young Finns Study; PLoS ONE
The contribution of childhood cardiorespiratory fitness and adiposity to inflammation in young adults; Obesity: a research journal
The cross-sectional association of sitting time with carotid artery stiffness in young adults; BMJ Open
The role of pharmacotherapy in the prevention and treatment of paediatric metabolic syndrome - implications for long-term health: part of a series on Pediatric Pharmacology, guest edited by Gianvincenzo Zuccotti, Emilio Clementi, and Massimo Molteni; Pharmacological Research
Tracking of muscular strength and power from youth to young adulthood: Longitudinal findings from the Childhood Determinants of Adult Health Study; Journal of Science and Medicine in Sport
Tracking of noninvasive ultrasound measurements of subclinical atherosclerosis in adulthood: Findings from the Cardiovascular Risk in Young Finns Study; Ultrasound in Medicine and Biology
Tracking of Serum Lipid Levels, Blood Pressure, and Body Mass Index from Childhood to Adulthood: The Cardiovascular Risk in Young Finns Study; Journal of Pediatrics
Use of B-Mode Ultrasound to Examine Preclinical Markers of Atherosclerosis: Image Quality May Bias Associations Between Adiposity and Measures of Vascular Structure and Function ; Journal of Ultrasound in Medicine
Using Pedometers to Estimate Ambulatory Physical Activity in Vietnam; Journal of Physical Activity & Health
Utility of Currently Recommended Pediatric Dyslipidemia Classifications in Predicting Dyslipidemia in Adulthood; Circulation
Vigorous physical activity and carotid distensibility in young and mid-aged adults; Hypertension Research
What the long term cohort studies that began in childhood have taught us about the origins of coronary heart disease; Current Cardiovascular Risk Reports
When and how to start prevention of atherosclerosis? Lessons from the Cardiovascular Risk in the Young Finns Study and the Special Turku Coronary Risk Factor Intervention Project ; Pediatric Nephrology
When to prevent cardiovascular disease? As early as possible: lessons from prospective cohorts beginning in childhood
Workplace Physical Activity Interventions: A Systematic Review; American Journal of Health Promotion
Youth overweight and metabolic disturbances in predicting carotid intima-media thickness, type 2 diabetes, and metabolic syndrome in adulthood: the cardiovascular risk in young Finns study; Diabetes Care

Research Projects

2012: 80th European Atherosclerosis Society Congress; University of Tasmania (UTAS)
An effective cardiovascular risk stratification system for children; National Health & Medical Research Council (NHMRC)
Cardiometabolic risk trajectories from childhood to midlife: finding pathways to better health; National Health & Medical Research Council (NHMRC)
Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: The childhood determinants of adult health study; National Heart Foundation (NHF)
Exposure to passive smoking in early-life and cardiovascular health in adulthood; University of Tasmania (UTAS)
Growing healthy hearts - how passive smoke exposure and elevated blood pressure early in life impacts adult cardiovascular health.; National Heart Foundation (NHF)
International Society for Behavioral Nutrition and Physical Activity (ISBNPA); University of Tasmania (UTAS)
Metabolite profiling for prediction of cardiometabolic risk in the Childhood Determinants of Adult Health Study; The Select Foundation (SelF)
Potentially modifiable risk factors in adolescence and high carotid artery intima-media thickness in young adults: population attributable risks from three prospective cohort studies; National Heart Foundation (NHF)
Understanding obesity trajectories from childhood to adulthood; Menzies Institute for Medical Research (MIMR)
Understanding the early-life pathways for adult type 2 diabetes using existing data from seven cohorts of the International Childhood Cardiovascular Cohort (i3C) Consortium; National Health & Medical Research Council (NHMRC)
Costan Magnussen - Discretionary Account

Research Candidate Supervision

Comparing and Developing Methods of Longitudinal Analysis for Different Types of Biological Data Sets