Web Access Research Portal

Researcher: Narkowicz, CK (Dr Christian Narkowicz)

Fields of Research

Pharmaceutical Sciences
Basic Pharmacology
Medicinal and Biomolecular Chemistry
Clinical Pharmacology and Therapeutics
Public Health and Health Services
Pharmacology and Pharmaceutical Sciences
Toxicology (incl. Clinical Toxicology)
Biologically Active Molecules
Medical Biochemistry and Metabolomics
Podiatry
Clinical Sciences
Medical Infection Agents (incl. Prions)
Technology
Traditional Aboriginal and Torres Strait Islander Medicine and Treatments
Nutrition and Dietetics
Medical Physiology
Agronomy
Organic Chemistry
Anaesthesiology
Plant Physiology
Gene Expression (incl. Microarray and other genome-wide approaches)
Health and Community Services
Neurology and Neuromuscular Diseases
Infectious Diseases
Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
Paediatrics
Crop and Pasture Biomass and Bioproducts
Epidemiology
Dental Therapeutics, Pharmacology and Toxicology
Primary Health Care
Agricultural Land Management
Complementary and Alternative Medicine
Pharmacogenomics
Sports Medicine

Research Objectives

Health
Skin and Related Disorders
Cardiovascular System and Diseases
Expanding Knowledge in the Chemical Sciences
Health Related to Ageing
Clinical Health (Organs, Diseases and Abnormal Conditions)
Public Health (excl. Specific Population Health)
Plant Production and Plant Primary Products
Preventive Medicine
Infectious Diseases
Nutrition
Blood Disorders
Education and Training Systems
Expanding Knowledge in Technology
Nervous System and Disorders
Skeletal System and Disorders (incl. Arthritis)
Cancer and Related Disorders
Pasture, Browse and Fodder Crops
Environmentally Sustainable Plant Production
Evaluation of Health Outcomes
Neurodegenerative Disorders Related to Ageing
Allied Health Therapies (excl. Mental Health Services)
Diagnostic Methods
Sugar Cane (Cut for Crushing)
Crop Protection Chemicals
Veterinary Pharmaceutical Treatments (e.g. Antibiotics)
Human Pharmaceutical Treatments (e.g. Antibiotics)

Career Best Publications

Research Publications

A low-volume microtitre plate assay for determination of the AFXa activity of enoxaparin; Out of the Wilderness Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium
A randomised trial of kunzea oil in comparison with amorolfine 5% solution nail lacquer for the treatment of onychomycosis in adults; Australasian Pharmaceutical Science Association Conference
A randomised trial of kunzea oil in comparison with amorolfine nail lacquer for the treatment of toenail onychomycosis; Australasian Pharmaceutical Science Association Annual Conference
A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins; Journal of Pharmaceutical and Biomedical Analysis
An evaluation of the clinical efficacy of kunzea oil formulations in the therapeuticmanagement of psoriasis in adults; Australasian Pharmaceutical Science Association Annual Conference
An examination of the essential oils of Tasmanian Kunzea ambigua, other Kunzea spp. and commercial kunzea oil; APSA annual conference Aus-CRS symposium
An examination of the essential oils of Tasmanian Kunzea ambigua, other Kunzea spp. and commercial kunzea oil; Journal of Essential Oil Research
Antioxidant activity of Carpobrotus rossii (pigface) extract; ASCEPT 2009
Antiplatelet activity of Carpobrotus rossii (pigface) extract; ASCEPT 2009
Beta2‑adrenergic stimulation increases energy expenditure at rest, but not during submaximal exercise in active overweight men; European Journal of Applied Physiology
Bronchopulmonary pharmacokinetics of (R)- salbutamol and (S)-salbutamol enantiomers in pulmonary epithelial lining fluid and lung tissue of horses; British Journal of Clinical Pharmacology
Characterisation and evaluation of the in vitro antimicrobial activity of Kunzea ambigua essential oil; Medicines design to delivery
Chemical content and antioxidant activity of Carpobrotus rossii, C. edulis and C. aequilaterus; Medicines design to delivery
Comparison of cyclooxygenase inhibition with two different doses of enteric coated aspirin in normal young and elderly subjects and elderly with cerebrovascular disease; Clinical and Applied Thrombosis/Hemostasis
Convolutindole A and Convolutamine H, New Nematocidal Brominated Alkaloids from the Marine Bryozoan Amathia convoluta; Journal of Natural Products
Determination of cotinine, 3'-hydroxycotinine, and their glucuronides in urine by ultra-high performance liquid chromatography; Analytical Letters
Ecophysiology of Carpobrotus rossii in Tasmania: Linking plant's antioxidant activity with a natural habitat; Ecological Questions
Effect of celecoxib on cyclooxygenase-2 expression and possible variants in a patient with Barrett's esophagus; Diseases of the Esophagus
Effect of chronic Carpobrotus rossii (pigface) ingestion on systolic blood pressure, body weight, blood lipids, haematological profile and in vitro vascular function in adult male rats; ASCEPT '10
Effective reversed-phase ion pair high-performance liquid chromatography method for the separation and characterization of intact low-molecular-weight heparins ; Analytical Biochemistry
Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells; Australian Neuroscience Society Annual Meeting
Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells; APSN 2012
Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice; PLoS One
Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice; Australian Neuroscience Society 31st Annual Meeting
Elevated plasma glutathione peroxidase concentration in rheumatoid arthritis; Medicines design to delivery
Enantioselective bronchopulmonary pharmacokinetics of salbutamol in horses; 2016 ACVIM Forum
Enantioselective disposition of (R)-salmeterol and (S)-salmeterol in urine following inhaled dosing and application to doping control; Drug Testing and Analysis
Evaluation of repellent properties of volatile extracts from the Australian native plant Kunzea ambigua against Aedes aegypti (Diptera: Culcidae); Journal of Medical Entomology
Free radical formation in patients undergoing hyperbaric oxygen therapy measured by spin trapping; 4th Annual Scientific Meeting of Diving and Hyperbaric Medicine, August 29-31, 1996
Further acetogenins from Tasmanian collections of Caulocystis cephalornithos demonstrating chemical variability; Biochemical Systematics and Ecology
Glucose tolerance is improved by supplementation with carpobrotus rossii flavanoids in insulin resistant mice; Thirty-Eighth Annual Scientific Meeting of The Nutrition Society of Australia
Hypolipidaemic effect of crude extract from Carpobrotus rossii (pigface) in healthy rats; Food and Chemical Toxicology
In vitro antioxidant, antiplatelet and anti-inflammatory activity of Carpobrotus rossii (pigface) extract; Journal of Ethnopharmacology
In vitro stability of enoxaparin solutions (20 mg/mL) diluted in 4% glucose; Clinical Therapeutics
Investigation of flavonoid metabolites after ingestion of Carpobrotus rossii extract in the rat; ASEAN Conference on Scientific and Social Science Research
Investigation of freezing- and thawing-induced biological, chemical, and physical changes to enoxaparin solution; Journal of Pharmaceutical Science
Investigation of the Chemistry and Antiparasitic Activity of Metabolites from Tasmanian Marine Organisms
Investigation of the effect of heating on the chemistry and antifactor Xa activity of enoxaparin; Journal of Pharmaceutical Science
Is the essential oil from the Australian native plant Kunzea ambigua repellent to mosquitoes?; Medicines design to delivery
Learning physiology from cardiac surgery patients; American Journal of Physiology (Advances in Physiology Education)
Modulation of flavonoid and tannin production of Carpobrotus rossii by environmental conditions; Environmental and Experimental Botany
New Amathamides with Nematocidal Activity from Tasmanian Collections of the Marine Bryozoans Amathia convoluta and Amathia wilsoni; 1st International Congress on the Chemistry of Natural Products
Physician and pharmacist care of varenicline users in a real-world setting; Asia Pacific Conference on Tobacco or Health 2010
Plasma glutathione peroxidase (GSH-Px) concentration is elevated in rheumatoid arthritis: a case–control study; Clinical Rheumatology
Plasma glutathione peroxidase by ELISA and relationship to selenium level; Clinica Chimica Acta
Prostanoid rebound following cessation of ibuprofen; Australian Society of Clinical and Experimental Pharmacologists and Toxicologists
Protoanemonin content variation between Clematis spp.: Leaf, Stem and Root; Natural Product Communications
Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil; Veterinary Record
Ranunculin the antibacterial constituent in Clematis aristata, and its mode of action; Proceedings of APSA
Reliability of Haemophilus influenzae biofilm measurement via static method, and determinants of in vitro biofilm production; Canadian Journal of Microbiology
Response to single dose and chronic ibuprofen in chronic back pain sufferers; Australasian Society of Clinical & Experimental Pharmacologists and Toxicologists
Safety and efficacy of kunzea oil-containing formulations for the management of psoriasis: A randomized, controlled trial; Journal of Clinical Pharmacy and Therapeutics
Saliva treatment of Dodoneae viscosa increases its antibacterial activity; Australasian Pharmaceutical Science Association Conference
Screening Tasmanian Marine Organisms for Antiparasitic Activity; Chemistry & Biology of Marine Organisms
Screening Tasmanian marine organisms for antiparasitic activity; Phytochemistry Reviews
Separation and characterisation of different low-molecular-weight heparins by reversed-phase ion-interaction high-performance liquid chromatography; Medicines design to delivery
Serum and urinary prostanoids following cessation of aspirin.; Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists
Size and sulfation are critical for the effect of heparin on APP processing and A beta production; Journal of Neurochemistry
Studies of chemical modification and formation of colon targeted microparticulates of Pachyman; Out of the Wilderness Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium
Studies on the potential anticancer compounds of Tasmanian Clematis species; Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium Hobart
The chemistry and pharmaceutical potential of Callitris spp. from Tasmania; Australasian Pharmaceutical Science Association Conference
The effect of heating on the chemistry and biological activity of enoxaparin; Medicines design to delivery
The effects of freezing and thawing on the AFXa activity of enoxaparin solution; Medicines design to delivery
The screening of chemical constituents, antitumour and antimicrobial activities of Tasmanian clematis species; Australasian Pharmaceutical Science Association Conference
Toenail onychomycosis: an important global disease burden; Journal of Clinical Pharmacy and Therapeutics
Treatment of pastern dermatitis with a formulation containing kunzea oil' a randomised controlled trail; Annual Conference of Australasian Pharmaceutical Science Association - Medicines design to delivery
Urinary prostanoid metabolites and serum thromboxane following recovery from cyclooxygenase inhibition with aspirin; Clinical and Applied Thrombosis/Hemostasis

Research Projects

Business Competition Grant - School of Pharmacy; University of Tasmania (UTAS)
Development of a Simple and Effective Ion-chromatagraphic Analysis for the Separation and Identification of Non-anticoagulant fractions of Enoxaparin; University of Tasmania (UTAS)
Drug Discovery, Biotechnology and Bridging the Gap using an Intermediary: Pilot Application to Novel Flavonoids with Potential to Reduce Cardiovascular Disease Risk; University of Tasmania (UTAS)
Identifying Novel Markers of Neonatal Sepsis; Royal Hobart Hospital Research Foundation (RHHRF)
Novel Biologically Active Fungal Metabolites from Endophytes of Tasmanian Plants; University of Tasmania (UTAS)
Walter and Eliza Hall Fungal Screening Project

Research Candidate Supervision

Application of Raman Spectroscopy to the Evaluation of Biofilm Formation and Virulence of Pathogenic Microorganisms
Assessment of Antibiotic Use
Drug Quality Assurance "Stability of Drugs Under Extreme Environmental Conditions"
Enoxaparin- Physicochemical Investigations into the Effects of Freezing and Heating
Investigation of Chemical Components and Pharmaceutical Potential of Carpobrotus Species
Kunzea Oil- Investigation of Composition, Bioactivity and Therapeutic Potential
Oxazolopyridines towards the Treatment of Human African Sleeping Sickness
Studies on the Use of Glycosaminoglycans for the Treatment of Alzheimer's Disease
The Pharmaceutical and Nutraceutical Potential of the Halophytic Plant Carpobrotus rossii
The Pharmaceutical Potential of Compounds from Tasmanian Clematis Species