Web Access Research Portal

Researcher: Snow, ET (Associate Professor Elizabeth Snow)

Fields of Research

Toxicology (incl. clinical toxicology)
Cancer genetics
Environmental assessment and monitoring
Cell development, proliferation and death
Tumour immunology
Gastroenterology and hepatology
Oncology and carcinogenesis
Epigenetics (incl. genome methylation and epigenomics)
Science, technology and engineering curriculum and pedagogy
Veterinary diagnosis and diagnostics
Other agricultural, veterinary and food sciences
Protein trafficking
Sport and exercise nutrition
Cancer cell biology
Gene expression (incl. microarray and other genome-wide approaches)
Cellular immunology
Pathology (excl. oral pathology)
Haematological tumours
Cell metabolism
Haematology
Food nutritional balance
Molecular targets
Clinical pharmacology and therapeutics

Research Objectives

Public health (excl. specific population health)
Clinical health
Expanding knowledge in the health sciences
Terrestrial biodiversity
Food safety
Learner and learning
Health related to ageing
Human pharmaceutical treatments
Preventive medicine
Diagnosis of human diseases and conditions
Human diagnostics

Career Best Publications

In vitro effect of arsenical compounds on glutathione related enzymes; Chemical Research in Toxicology
Arsenic and heavy metal contamination of vegetables grown in Samta village, Bangladesh; Science of the Total Environment
Arsenic toxicity is enzyme specific and arsenic inhibition of DNA repair is not caused by direct inhibition of repair enzymes; DNA Repair
Arsenic, mode of action at biologically plausible low doses: what are the implications for low dose cancer risk?; Toxicology and Applied Pharmacology
Effect of Arsenic on Transcription Factor AP-1 and NF-kB DNA Binding Activity and Related Gene Expression; Toxicology Letters
Environmental factors affecting transcription of the human L1 Hs retrotransposon: 2. Stressors; Mutagenesis
Up-regulation of glutathione-related genes and enzyme activities in cultured human cells by sub-lethal concentrations of inorganic arsenic; Toxicological Sciences

Research Publications

In vitro effect of arsenical compounds on glutathione related enzymes; Chemical Research in Toxicology
A comparison of trace element concentrations in cultured and wild carp (Cyprinus carpio) of Lake Kasumigaura, Japan. ; Ecotoxicology and Environmental Safety
A little goes a long way: Low levels of oxidative stress trigger hormesis, an adaptive cellular response; MEPSA 2007 (Mutagenesis and Experimental Pathology Society of Australasia)
A possible role for chromium(III) in genotoxicity; Environmental Health Perspectives
Age and exposure to arsenic alter base excision repair transcript levels in mice; Mutagenesis
Alteration of GSH level, gene expression and cell transformation in NIH3T3 cells by chronic exposure to low dose of arsenic; Arsenic Exposure and Health Effects V
An Escherichia coli plasmid-based, mutational system in which supF mutants are selectable: Insertion elements dominate the spontaneous spectra; Mutation Research: fundamental and molecular mechanisms of mutagenesis
Arsenic and heavy metal contamination of rice, pulses and vegetables grown in Samta village, Bangladesh. ; Fifth International Conference on Arsenic Exposure and Health Effects
Arsenic and heavy metal contamination of vegetables grown in Samta village, Bangladesh; Science of the Total Environment
Arsenic and the DNA É“ and AP endonuclease promoters; Mutagenesis & Experimental Pathology Society of Australasia (MEPSA)
Arsenic and the Human DNA Polymerase b and AP Endonuclease I Promoters; 9th International Conference on Environmental Mutagenesis (ICEM)
Arsenic and the Human DNA Polymerase É“ and AP Endonuclease I Promoters; Combio 2005
Arsenic concentrations in Yabbies, Cherax destructor Clark (Decapoda: Parastacidea) exposed to elevated levels in dams in and around Ballarat; Mutagenesis & Experimental Pathology Society of Australasia (MEPSA) Meeting
Arsenic concentrations in yabbies, Cherax destructor Clark, exposed to elevated levels as a results of mining activity in and around Ballarat, Victoria; Interact 2006: ĎAir Water & Earth
Arsenic exposure disrupts epigenetic regulation of SIRT1 in human keratinocytes; Toxicology and Applied Pharmacology
Arsenic speciation in the freshwater crayfish, Cherax destructor Clark; Science of The Total Environment: An International Journal for Scientific Research Into The Environment and Its Relationship With Man
Arsenic toxicity is enzyme specific and arsenic inhibition of DNA repair is not caused by direct inhibition of repair enzymes; DNA Repair
Arsenic, mode of action at biologically plausible low doses: what are the implications for low dose cancer risk?; Toxicology and Applied Pharmacology
Arsenic, mode of action at biologically plausible low doses: what are the implications for low dose cancer risk? ; Tenth International Conference of Toxicology (ICTX)
Arsenic-Induced Hormesis: Underlying Mechanisms and Timing; Fifth Annual Conference on Hormesis: Implications for Toxicology, Medicine & Risk Assessment
Base‑pairing properties of O 6-methylguanine in template DNA during in vitro DNA replication; Journal of Biological Chemistry
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework; Toxicology and Applied Pharmacology
Comparison of Tissue Dosimetry in the Mouse Following Chronic Exposure to Arsenic Compounds; Journal of Toxicology and Environmental Health. Part A
Effect of Arsenic on Transcription Factor AP-1 and NF-kB DNA Binding Activity and Related Gene Expression; Toxicology Letters
Effects of micromolar As(III) on DNA ligase activity and gene expression in human fibroblasts and keratinocytes,; Mutagenesis & Experimental Pathology Society of Australasia (MEPSA) Meeting
Environmental factors affecting transcription of the human L1 Hs retrotransposon: 1. Steroid hormone-like agents. ; Mutagenesis
Environmental factors affecting transcription of the human L1 Hs retrotransposon: 2. Stressors; Mutagenesis
ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1); PLOS One
Exposure to As(III) and As(V) changes the Ca2+-activation properties of the two major fibre types from the chelae of the freshwater crustacean Cherax destructor; Aquatic Toxicology
Hormesis: A general response to perturbations of homeostasis and oxidative stress?; Mutagenesis & Experimental Pathology Society of Australasia (MEPSA) Meetin
Human Papilloma Virus (HPV) in Barrett's Oesophagus; Joint Meeting of SFRR(A) and MEPSA on Redox Processes in Chemistry, Biology & Medicine
Human papilloma virus in Barrett's oesophagus; 10th International Congress of Environmental Mutagens (ICEM)
Impact of arsenic exposure on levels of short patch base excision repair transcripts in lactating and adult mice; 10th International Congress of Environmental Mutagens (ICEM)
Impact of arsenic exposure on levels of short-patch base excision repair transcripts in lactating and adult mice; Joint Meeting of SFRR(A) and MEPSA on Redox Processes in Chemistry, Biology & Medicine
Is HPV a significant factor in the development of esophageal adenocarcinoma in Tasmania?; 2008 AHMRC Meeting
Metal carcinogenesis: Mechanistic implications
Metal Ions and Carcinogenesis; Cancer: Cell Structures, Carcinogens and Genomic Instability
Modulation of arsenic-induced epidermal growth factor receptor pathway signalling by resveratrol; Chemico-Biological Interactions
Modulation of DNA polymerase beta-dependent base excision repair in cultured human cells after low dose exposure to arsenite; Toxicology and Applied Pharmacology
Onions for health
Onions for Health (II)
Protective effects of food antioxidants on arsenic toxicity; Joint Meeting of SFRR(A) and MEPSA on Redox Processes in Chemistry, Biology & Medicine
Protective effects of food antioxidants on arsenic toxicity; 10th International Congress of Environmental Mutagens (ICEM)
Regulation of Redox and DNA Repair Genes by Arsenic: Low Dose Protection Against Oxidative Stress?; Arsenic Exposure and Health Effects V
Self-reported Student Confidence in Troubleshooting Ability Increases After Completion of an Inquiry-Based PCR Practical; Biochemistry and Molecular Biology Education
SIRT1 inhibition restores apoptotic sensitivity in p53-mutated human keratinocytes; Toxicology and Applied Pharmacology
SIRT1 modulates miRNA processing defects in p53-mutated human keratinocytes; Journal of Dermatological Science
Sub-toxic arsenite induces a multi-component protective response against oxidative stress in human cells,; Fourth International Conference on Arsenic Exposure and Health Effects
The Diverse Effects of Arsenic on the Multi-Functional Protein Ref-1/ AP Endonuclease; 9th International Conference on Environmental Mutagenesis (ICEM)
Time- and Dose-Dependent Changes in BER Capacity in Response to Arsenic; 2006 Australian Health & Medical Research Congress (AHMRC)
Total arsenic accumulation in yabbies (Cerax destructorClark) exposed to elevated arsenic in Victorian gold mining areas; Environmental Toxicology and Chemistry
Total arsenic concentrations in native freshwater crayfish from gold mining regions of Australia
Toxicity and carcinogenicity of nickel compounds
Toxicological Responses of Human Cells to Low Dose As - Implications for Risk Assessment; 9th International Conference on Environmental Mutagenesis (ICEM)
Toxicological responses of human cells to low dose As: implications for risk assessment; International Conference on Metals in the Environment (ICHMET)
Transcriptionally Active Human Papillomavirus Is Strongly Associated With Barrett's Dysplasia and Esophageal Adenocarcinoma; The American Journal of Gastroenterology
Up-regulation of glutathione-related genes and enzyme activities in cultured human cells by sub-lethal concentrations of inorganic arsenic; Toxicological Sciences
Viral load and Integration status of High-Risk Human Papillomaviruses in the Barrett's metaplasiaĖdysplasiaĖadenocarcinoma sequence; American Journal of Gastroenterology

Research Projects

Epigenetic Regulation of Tumour Supressors in Skin Cancer; Cancer Council of Tasmania (CCT)
Estimation of HPV Infection Rates in GERD, Barrett's Oesophagus and Oesophageal Adenocarcinoma; Clifford Craig Foundation (CCFoundation)
Etiologic Role of Human Papilloma Virus (HPV) Infection in Barrett's Oesophagus and Its Implication in Oesophageal Adenocarcinoma; Clifford Craig Foundation (CCFoundation)
Human Leucocyte Antigen (HLA) Expression Shift in Oesophageal Dysplasia: A Student Project; Clifford Craig Foundation (CCFoundation)
Pilot Study of Gene Expression & Protein Regulation in Barrett's Oesophagus and Oesophageal Adenocarcinoma; Clifford Craig Foundation (CCFoundation)
The Potential Role of Human Papilloma Virus in Short and Long Segment Barrett's Oesophagus and the Development of Dysplasia; Clifford Craig Foundation (CCFoundation)
Arsenic-Glutathione Interactions and Skin Cancer
Biotechnology Institute Containment Facility

Research Candidate Supervision

Epigenetic mechanisms of arsenic-induced transformation in human keratinocytes
Further Immunohistochemical (IHC) and Ultrastructural Characterisation of Devil Facial Tumour Disease (DFTD) in the Tasmanian Devil (Sarcophilu harisii)