Web Access Research Portal

Researcher: Adams, MJ (Dr Murray Adams)

Fields of Research

Haematology
Cardiology (incl. cardiovascular diseases)
Exercise physiology
Rheumatology and arthritis
Basic pharmacology
Nephrology and urology
Haematological tumours
Immunology
Clinical pharmacology and therapeutics
Pharmacology and pharmaceutical sciences
Nutrition and dietetics
Systems physiology
Biochemistry and cell biology
Nutritional science
Public health nutrition
Medical physiology
Sports science and exercise
Anaesthesiology
Autoimmunity
Molecular targets
Health services and systems
Traditional, complementary and integrative medicine
Cell metabolism
Clinical sciences
Cellular interactions (incl. adhesion, matrix, cell wall)

Research Objectives

Diagnosis of human diseases and conditions
Clinical health
Specific population health (excl. Indigenous health)
Nutrition
Human pharmaceutical treatments
Health status (incl. wellbeing)
Allied health therapies (excl. mental health services)
Expanding knowledge in the health sciences
Health related to ageing

Career Best Publications

Anti-tissue factor pathway inhibitor activity in patients with primary antiphospholipid syndrome; British Journal of Haematology
Anti-tissue factor pathway inhibitor activity in subjects with antiphospholipid syndrome is associated with increased thrombin generation; Haematologica
The effects of tissue factor pathway inhibitor and anti-beta2-glycoprotein I IgG on thrombin generation; Haematologica

Research Publications

β2GP1, anti-β2GP1 antibodies and platelets: key players in the antiphospholipid syndrome; Antibodies
A comparative study of functional assays for tissue factor pathway inhibitor using normal and clinical samples; Blood Coagulation and Fibrinolysis
A rapid flow cytometric technique for the detection of platelet-monocyte complexes, activated platelets and platelet-derived microparticles; International Journal of Laboratory Hematology
A role for the tissue factor pathway in the pathogenesis of the antiphospholipid syndrome
ACL Antibodies and TFPI Extend CAT Lag Phase; Annual Combined ASM of the HSANZ/ANZBT/ASTH
Acquired and genetic thrombotic risk factors in the athlete; Seminars in Thrombosis and Hemostasis
Acute effect of a high-carbohydrate low-fat meal on platelet aggregation; Platelets
Analysis of TFPI activity in patients prone to DVT: increased activity in APS but not FVL who have suffered DVT; 7th Combined ASM of the HSANZ/ANZBT/ASTH
Anti-β2GP1 antibodies have variable effects on platelet aggregation; Pathology
Anti-B2GP1 Antibodies have Variable Effects on Platelet Aggregation; Annual Combined ASM of the HSANZ/ANZBT/ASTH and the APSTH
Anti-TFPI activity in patients with antiphospholipid syndrome; XVIIIth Congress of the International Society of Thrombosis and Haemostasis
Anti-TFPI activity in patients with APS; 3rd European Forum on Antiphospholipid Antibodies
Anti-tissue factor pathway inhibitor activity in patients with primary antiphospholipid syndrome; British Journal of Haematology
Anti-tissue factor pathway inhibitor activity in subjects with antiphospholipid syndrome is associated with increased thrombin generation; Haematologica
Antiplatelet activity of Carpobrotus rossii (pigface) extract; ASCEPT 2009
Assessment of platelet function by flow cytometry; Australian Society of Medical Research Meeting
Assessment of platelet function by flow cytometry; 8th Combined ASM of the HSANZ/ANZBT/ASTH
Assessment of thrombin generation
Assessment of Thrombin Generation: Useful or Hype?; Seminars in Thrombosis and Haemostasis
Association between TFPI activity, promoter polymorphisms and venous thromboembolism in patients with FVL; 5th Combined ASM of the HSANZ/ANZBT/ASTH
Association of von Willebrand factor blood levels with exercise hypertension; European Journal of Applied Physiology
Australasian Society of Thrombosis and Haemostasis Scientific Workshop; Australasian Society of Thrombosis and Haemostasis Scientific Workshop
Book Review: Biomedical Sciences Explained: Haematology (CJ Pallister); Australian Journal of Medical Science
Book review: Pediatric and Adolescent Medicine Volume 17 Controversies in Pediatric and Adolescent Hematology; Australian Journal of Medical Science
Book review: SickKids Handbook of Pediatric Thrombosis and Hemostasis; Australian Journal of Medical Science
Braveheart mum leading lupus battle
Capsaicin-induced death of human haematological malignant cell lines is independent of TRPV1 activation; Pharmacology
Changes to fibrinolysis in patients with systemic lupus erythematosus are associated with endothelial cell damage and inflammation, but not antiphospholipid antibodies; Blood Coagulation & Fibrinolysis
Characterisation of anti-TFPI activity in subjects with the antiphospholipid syndrome; 4th Combined ASM of the HSANZ/ANZBT/ASTH
Clifford Craig Medical Trust Grants
Combined effect of plasma antithrombin III and platelet factor 4 levels in the development of heparin resistance during cardiac bypass surgery; 4th Combined ASM of the HSANZ/ANZBT/ASTH
Compression socks and the effects on coagulation and fibrinolytic activation during marathon running; European Journal of Applied Physiology
D-Dimer levels at different stages of pregnancy in Australian women: A single centre study using two different immunoturbidimetric assays; Thrombosis Research
Deep vein thrombosis in a well-trained masters cyclist, is popliteal vein entrapment syndrome to blame?; Journal of Thrombosis and Thrombolysis
Does chilli affect platelet aggregation?; 36th Annual Conference of Association of Clinical Biochemists of India
Effect of Capsaicin and Dihydrocapsaicin on in vitro Blood Coagulation and Platelet Aggregation; Thrombosis Research
Effect of chilli intake on platelet aggregation; Joint Annual Scientifc Meeting of the Nutrition Society of Australia & the Nutrition Society of New Zealand
Effect of Lipoproteins on the Release of Tissue Factor Pathway Inhibitor and Expression of Tissue Factor in Endothelial Cells; Annual Combined ASM of the HSANZ/ANZBT/ASTH
Effect of vanilloid-like agents on platelet aggregation is not mediated through cannabinoid receptors; Thirty-Eighth Annual Scientific Meeting of The Nutrition Society of Australia
Effect of whole-body mild-cold exposure on arterial stiffness and central haemodynamics: a randomised, cross-over trial in healthy men and women; European Journal of Applied Physiology
Effects of antiphospholipid antibodies on in vitro platelet aggregation; Clinical and Applied Thrombosis/Hemostasis
Emerging Technologies in Hemostasis Diagnostics: A Report from the Australasian Society for Thrombosis and Haemostasis Emerging Technologies Group
Exercise Causing Thrombosis; The Physician and Sportsmedicine: A Peer Reviewed Journal of Medical Aspects of Sports, Exercise and Fitness
Exercise in the fight against thrombosis: friend or foe?; Seminars in Thrombosis and Haemostasis
Expression of CCR6 on B cells in systemic lupus erythematosus patients; Clinical Rheumatology
Expression of recombinant tissue factor pathway inhibitor in an insect cell system; Australian Society of Medical Research Meeting
Flow cytometric analysis of transient receptor potential vanilloid 1 (TRPV1) in human leukocyte populations; Annual Combined ASM of the ASCEPT/AuPS/HBRCA
Food and Postprandial Platelet Aggregation in Healthy Individuals; Annual Combined ASM of the HSANZ/ANZBT/ASTH
Further insight into the Heparin-Releasable and Glycosylphosphatidylinositol-lipid anchored forms of tissue factor pathway inhibitor; Clinical and Applied Thrombosis and Haemostasis
Further Investigations of Lupus Anticoagulant Interference in a Functional Assay for Tissue Factor Pathway Inhibitor; Thrombosis Research
Further investigations of the effects of anti-β2GP1 antibodies on collagen-induced platelet aggregation; Clinical and Applied Thrombosis - Hemostasis
Generation of monospecific polyclonal antibodies to the kunitz domains of tissue factor pathway inhibitor; 1st North Sea Conference on Thrombosis and Haemostasis
Global Assays of Haemostasis: Where to now?; Australasian Society of Thrombosis and Haemostasis Scientific Workshop
Grant for Pilot Kidney Study
Heparin has variable effects on the release of glycosylphosphatidylinositol lipid anchored TFPI from human umbilical vein endothelial cells; XXth Congress of the International Society of Thrombosis and Haemostasis
Heterogeneous heparin induced TFPI release in patients undergoing cardiopulmonary bypass; XVIIIth Congress of the International Society of Thrombosis and Haemostasis
Hypercoaguability in chronic kidney disease is associated with coagulation activation but not endothelial function; Thrombosis Research
Hypercoagulability in chronic renal failure: activation of the tissue factor pathway of coagulation and impairment of endogenous anticoagulants in patients enrolled in the SAFIRE study; 39th ASM of the Australian and New Zealand Society of Nephrology
Hypolipidaemic effect of crude extract from Carpobrotus rossii (pigface) in healthy rats; Food and Chemical Toxicology
IgG fractions from subjects with the antiphospholipid syndrome demonstrated inhibitor activity against TFPI and increased thrombin generation; 5th Combined ASM of the HSANZ/ANZBT/ASTH
Impaired Control of the Tissue Factor Pathway in SLE; Annual Combined ASM of the HSANZ/ANZBT/ASTH
Impaired control of the tissue factor pathway of blood coagulation in systemic lupus erythematosus; Lupus
Impaired control of the tissue factor pathway of coagulation in Tasmanian patients with systemic lupus erythematosus; 9th International Congress on Systemic Lupus Erythematosus . Vancouver 2010
In vitro antioxidant, antiplatelet and anti-inflammatory activity of Carpobrotus rossii (pigface) extract; Journal of Ethnopharmacology
Inhibition of Human Haematological Malignant Cell Lines by Capsaicin is not TRPV1-Mediated; Annual Combined ASM of the HSANZ/ANZBT/ASTH and the APSTH
Inhibition of platelet aggregation by vanilloid-like agents is not mediated by transient receptor potential vanilloid-1 channels or cannabinoid receptors; Clinical and Experimental Pharmacology and Physiology
Interference by Lupus Anticoagulant in a Functional Assay for Tissue Factor Pathway Inhibitor; Thrombosis Research
Investigation of tissue factor pathway inhibitor promoter polymorphisms in patients with antiphospholipid syndrome: decreased TFPI activity in a patient homozygous for the T-287-C polymorphism; 6th Combined ASM of the HSANZ/ANZBT/ASTH
Leukocyte TRPV1 Expression and Function in Health and Disease; AIMS/AACB 2011
Lupus research
Lupus research
Lupus research
Lupus research gets $10,000 helping hand
Measurement of lupus anticoagulants: An update on quality in laboratory testing; Seminars in Thrombosis and Hemostasis
Measurement of Tissue Factor Procoagulant Activity and the Effect of Plasma Derived Microparticles; 6th Combined ASM of the HSANZ/ANZBT/ASTH
Metabolomics in hypertension; Journal of Hypertension
Novel Considerations in the Pathogenesis of the Antiphospholipid Syndrome: Involvement of the Tissue Factor Pathway of Blood Coagulation; Seminars in Thrombosis and Hemostasis
Nutritional compounds influence tissue factor expression and inflammation of chronic kidney disease patients in vitro; Nutrition: The International Journal of Applied and Basic Nutritional Sciences
Polymorphisms in the TFPI gene are not associated with ischaemic stroke; Blood Coagulation and Fibrinolysis
Polymorphisms of the tissue factor pathway inhibitor gene are associated with venous thromboembolism in the antiphospholipid syndrome and carriers of factor V Leiden; Blood Coagulation and Fibrinolysis
Poor correlation using two functional amidolytic methods for tissue factor pathway inhibitor; 1st North Sea Conference on Thrombosis and Haemostasis
Postprandial platelet aggregation: effects of different meals and glycemic index; European Journal of Clinical Nutrition
Reduced tissue factor pathway inhibitor activity in patients with the antiphospholipid syndrome; British Society of Haematology Meeting
Serum enhances the heparin dependent release of tissue factor pathway inhibitor from human umbilical vein endothelial cells; 6th Combined ASM of the HSANZ/ANZBT/ASTH
Serum enhances the heparin dependent release of tissue factor pathway inhibitor from umbilical vein endothelial cells; Australian Society of Medical Research Symposium
Serum metabolic profile predicts adverse central haemodynamics in patients with type 2 diabetes mellitus; Acta Diabetologica
Spironolactone reduces aortic stiffness via blood pressure-dependent effects of canrenoate; Metabolomics
Stem cells to save lives in WA
Synergistic inhibitory effect of capsaicin and dihydrocapsaicin on in vitro platelet aggregation and thromboxane formation; Blood Coagulation and Fibrinolysis
Tertiary Haemostasis: What do we Teach, What Should we Teach?; The Australasian Society of Thrombosis and Haemostasis Scientific Workshop
TFPI activity and Anit-TFPI Antibodies in APS; 10th International Symposium on Antiphospholipid Antibodies
TFPI dependent FXa generation in patients with the antiphospholipid syndrome; IXth International Symposium on Antiphospholipid Antibodies
The 2007 Annual Scientific Meeting of the Haematology Society of Australia and New Zealand, the Australian and New Zealand Society of Blood Transfusion and the Australasian Society of Thrombosis and Haemostasis; 2007 Annual Scientific Meeting of the Haematology Society of Australia and New Zealand, the Australian and New Zealand Society of Blood Transfusion and the Australasian Society of Thrombosis and Haemostasis
The 2008 Annual Scientific Meeting of the Haematology Society of Australia and New Zealand, the Australian and New Zealand Society of Blood Transfusion and the Australasian Society of Thrombosis and Haemostasis; The 2008 Annual Scientific Meeting of the Haematology Society of Australia and New Zealand, the Australian and New Zealand Society of Blood Transfusion and the Australasian Society of Thrombosis and Haemostasis.
The Effect of Capsaicin and Dihydrocapsaicin on Blood Coagulation and Platelet Aggregation in vitro; ASM Haematology Society of Australia and New Zealand, Australian and New Zealand Society of Blood Transfusion & Australasian Society of Thrombosis and Haemostasis
The effects of alcohol on coagulation and fibrinolytic factors: a controlled trial; Blood Coagulation and Fibrinolysis
The effects of tissue factor pathway inhibitor and anti-beta2-glycoprotein I IgG on thrombin generation; Haematologica
The Effects of Vanilloid-Like Agents on Platelet Aggregation; Annual Combined ASM of the ASCEPT/AuPS/HBRCA
The Effects of Vanilloid-Like Agents on Platelet Aggregation; Annual Combined ASM of the HSANZ/ANZBT/ASTH
The tissue factor pathway in ischaemic stroke patients; 6th Combined ASM of the HSANZ/ANZBT/ASTH
The tissue factor pathway in ischemic stroke; Blood Coagulation and Fibrinolysis
Thrombosis in Systemic Lupus Erythematosus; Seminars in Thrombosis and Haemostasis
Thrombosis in systemic lupus erythematosus: Role of impaired fibrinolysis
Time of day and short-duration high-intensity exercise influences on coagulation and fibrinolysis; European Journal of Sport Science
Tissue factor pathway inhibitor activity is not increased in normal and hyperlipidaemic serum after treatment with two dispersing agents; XVIIIth Congress of the International Society of Thrombosis and Haemostasis
Tissue Factor Pathway Inhibitor Antigen and Activity in 96 Patients Receiving Heparin for Cardiopulmonary Bypass; Journal of Cardiothoracic and Vascular Anesthesia
Tissue Factor Pathway Inhibitor: A Brief Review
Tissue Factor Pathway Inhibitor: A Central Role in Modern Coagulation (Review)
Tissue factor pathway inhibitor: New insights into an old inhibitor; Seminars in Thrombosis and Hemostasis
Tissue factor pathway inhibitor: Regulator of the tissue factor pathway of coagulation and a future antithrombotic agent?; Australian Journal of Medical Science
Tissue Factor Pathway Inhibitor: Then and Now
Tissue factor procoagulant activity and tissue factor pathway inhibitor activity in patients with primary hyperlipidaemia; XVIIIth Congress of the International Society of Thrombosis and Haemostasis
Towards the Future 1: Thrombin Generation: Useful or Hype?; International Society of Laboratory Hematology (ISLH).
Up-regulation of the tissue factor pathway and impairment of the protein C pathway in subjects with chronic renal failure; 5th Combined ASM of the HSANZ/ANZBT/ASTH
Vanilloid Like Agents: Potential Therapeutic Targeting of Platelets?
Vanilloid-like agents inhibit aggregation of human platelets; Thrombosis Research
Vanilloid-Like Agents Inhibit in vitro Platelet Aggregation; Annual Combined ASM of the HSANZ/ANZBT/ASTH and the APSTH
Variable Effects of Antiphospholipid Antibodies on in vitro Platelet Aggregation; Annual Combined ASM of the HSANZ/ANZBT/ASTH
Variable effects of antiphospholipid antibodies on in vitro platelet aggregation: possible pro- and anticoagulant mechanisms?; 9th Internationsl Congress on Systemic Lupus Erythematosus Vancouver 2010

Research Projects

9th International Congress on Systemic Lupus Erythematosus, Vancouver, Canada; University of Tasmania (UTAS)
A Pilot Study to Investigate the Effect of Capsaicinoids on in vitro Platelet Aggregation and Blood Coagulation; University of Tasmania (UTAS)
A Pilot Study to Investigate the Tissue Factor Pathway of Blood Coagulation in Systemic Lupus Erythematosus; Clifford Craig Foundation (CCFoundation)
Blood Clots in Systemic Lupus Erythematosus: The Role of Impaired Fibrinolysis; Clifford Craig Foundation (CCFoundation)
Effect of Acute Climatic Changes on Blood Pressure, Blood Vessel Function and Blood Clotting in Type II Diabetes; Clifford Craig Foundation (CCFoundation)
Evaluation of Platelet Activation and Function and the Extracellular Regulatory Kinase Pathway in Haematological Disorders Pre and Post Treatment Using Flow Cytometry; Clifford Craig Foundation (CCFoundation)
Human SLE: Searching new biomarkers and potential targets for therapy; The Lupus Association of Tasmania (LAT)
Immune Cells in a Sick Environment: Lymphocyte Function in Chronic Kidney Disease; Clifford Craig Foundation (CCFoundation)
Inhibition of platelet aggregation by vanilloid-like agents: a novel antithrombotic mechanism in patients with Systemic Lupus Erythematosus?; Clifford Craig Foundation (CCFoundation)
Podiums are better than pulmonary thromboembolisms? Health risks associated with prolonged travel in athletes; Exercise & Sports Science Australia (ESSA)
The Effects of Meals with Different Composition on Metabolic, Vascular and Haemostatic Parameters; Clifford Craig Foundation (CCFoundation)
The Influence of Nutritional Supplements on Inflammatory Markers and Tissue Factor in Chronic Kidney Disease; Clifford Craig Foundation (CCFoundation)
Transient Receptor Potential Vanilloid-1 (TRPV1): A Potential Novel Therapeutic Target in Blood Cancers?; Clifford Craig Foundation (CCFoundation)
A Pilot Study to Investigate the Effect of Atorvastatin on the Tissue Factor Pathway and Natural Inhibitors of Coagulation in Microalbuminuric Type 1 Diabetic Subjects
A Pilot Study to Investigate the Tissue Factor Pathway and Natural Inhibitors of Coagulation in Chronic Renal Failure

Research Candidate Supervision

A Novel Human Embryonic Stem Cell Derived Model of Trabecular Meshwork Tissue- Investigation of the Molecular Mechanisms of Complex Disease
A Pilot Study Evaluating Platelet Activation, Function and Extracellular Regulatory Linase Pathway in Haematological Disorders Pre and post Treatment Using Flow Cytometry
A Pilot Study to Determine the Prevalence of Thyroid Disease in Correlation with Iron Deficiency within
Acquired Macrolide Resistance Genes in Non-typeable Haemophilus influenzae
Analysis of Elite Athletes Sports Performance Following Transmeridian Long-Haul Travel to Reduce Negative Effects and Examination of Haematological Health Risks as a
Cardiovascular Abnormalities Associated With High Blood Pressure
Inhibition of Platelet Aggregation by Vanilloid-Like Agents- A Novel Antithrombotic Mechanism in Patient with Systemic Lupus Erythematosus?
Long Haul Travel and the Effect on Athletic Performance
New Insights into the Mechanisms of B-Lactam Resistance in Haemophilus influenzae
Phenotypic and genotypic characterisation of altered penicillin-binding protein 3 (PBP3) mediated resistance in Haemophilus influenzae and Haemophilus haemolyticus
The Effects of Vanilloid-like Agents on Platelet Aggregation
Transient Receptor Potential Vanilloid 1 (TRPV1) in Haematological Malignancies