Web Access Research Portal

Researcher: Soltani Abhari, A (Dr Amir Soltani Abhari)

Fields of Research

Respiratory diseases
Primary health care

Research Objectives

Clinical health
Preventive medicine

Career Best Publications

Research Publications

A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study; International Journal of COPD
Airway Angiogenesis And basement Membrane Remodeling In Smokers And Chronic Obstructive pulmonary Disease: cross-sectional And Longitudinal Studies
Airway histone deacetylase-2 increases after smoking cessation, but is not affected by inhaled corticosteroids in Chronic Obstructive Pulmonary Disease (COPD): A randomized controlled trial; American Thoracic Society (ATS)
Airway Remodeling in Chronic Obstructive Pulmonary Disease (COPD), a Review
Angiogenesis: A potentially critical part of remodelling in chronic airway diseases?; Pharmacology & Therapeutics
Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional study ; Respiratory Research
Basement membrane remodelling in COPD responds to inhaled corticosteroids; The Thoracic Society of Australia & New Zealand Annual Scientific Meeting
Changes in airway histone deacetylase2 in smokers and COPD with inhaled corticosteroids: A randomized controlled trial; PLoS One
Comparing factor VIII with collagen IV for immuno-staining of vessels; The Thoracic Society of Australia & New Zealand Annual Scientific Meeting
Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease
Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease; Cochrane Database of Systematic Reviews
Distinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same disease; Histopathology
Epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD) airways is attenuated by inhaled corticosteroids (ICS); British Thoracic Society
Epithelial mesenchymal transition (EMT) in large airways is attenuated by inhaled fluticasone propionate (FP) in COPD: a randomized controlled trial; The 8th International Young Investigators’ Meeting (YIM) on Airway Smooth Muscle and Fibroblast Biology
Epithelial mesenchymal transition (EMT) in patients with chronic obstructive disease (COPD); The Thoracic Society of Australia & New Zealand Annual Scientific Meeting
Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease; Respiratory Research
Fluticasone propionate attenuates epithelial mesenchymal transition (EMT) in COPD; Respirology, 17 (Supp 1)
Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD; International Journal of COPD
Inhaled corticosteroids (ICS) attenuate epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD) - implications for lung cancer prophylaxis; Australian Lung Cancer Conference (ALCC)
Inhaled corticosteroids (ICS) attenuates epithelial mesenchymal transition (EMT) in COPD: a key to understanding long term benefits; European Respiratory Society Annual Congress
Inhaled corticosteroids in airway remodelling in COPD; Thorax
Inhaled corticosteroids is effective on only some aspects of bronchial vascular remodelling in COPD; Thoracic Society of Australia and New Zealand
Inhaled fluticasone propionate (FP) restores angiogenesis in the airway lamina propria of current smokers with COPD: a randomized controlled trial; European Respiratory Society Annual Congress
Intermediate filament vimentin and potential role in epithelial mesenchymal transition (EMT); Vimentin Concepts and Molecular Mechanisms
Mast cells in COPD airways: relationship to bronchodilator responsiveness and angiogenesis; European Respiratory Journal
Optimum duration of corticosteroid therapy for acute exacerbations of Chronic Obstructive Pulmonary Disease
Prospective outcomes in patients with acute exacerbations of chronic obstructive pulmonary disease presenting to hospital: a generalisable clinical audit; Internal medicine journal
Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease ; Respirology
Reticular basement membrane vessels are increased in COPD bronchial mucosa by both factor VIII and collagen IV immunostaining and are hyperpermeable; Journal of Allergy
Smoking cessation but not inhaled corticosteroids (ICS) can increase histone deacetylase 2 (HDAC2)] in COPD ; The European Respiratory Journal
Smoking has potential to initiate basement membrane disruption and epithelial mesenchymal transition in COPD ; European Respiratory Society Annual Congress
Smoking has potential to initiate epithelial mesenchymal transition (EMT) in the airway mucosa
Transforming growth factor - beta 1 (TGF-β 1) expression is related to reticular basement membrane (Rbm) hypervascularity in smokers and COPD; European Respiratory Society Annual Congress
Vascular and basement membrane remodelling in smokers and COPD; European Respiratory Journal
Vascular remodelling in asthma
Vessel-associated transforming growth factor-beta1 (TGF-β 1) is increased in the bronchial reticular basement membrane in COPD and normal smokers; PLoS One
Vessel-associated transforming growth factor-Beta1 (TGF-β1) expression is increased in COPD airway; Respirology, 17 (Supp 1)

Research Projects

Investigation of airway inflammation in COPD; GlaxoSmithKline Australia (GSKA)
Sypkes Respiratory Medicine Research Fellowship: Dr Amir Soltani; Royal Hobart Hospital Research Foundation (RHHRF)

Research Candidate Supervision