Web Access Research Portal

Researcher: Jacobson, GA (Dr Glenn Jacobson)

Research Fields

Pharmaceutical Sciences
Pharmacology and Pharmaceutical Sciences
Clinical Pharmacology and Therapeutics
Epidemiology
Basic Pharmacology
Preventive Medicine
Cardiology (incl. Cardiovascular Diseases)
Public Health and Health Services
Toxicology (incl. Clinical Toxicology)
Respiratory Diseases
Primary Health Care
Animal Protection (Pests and Pathogens)
Medical Biochemistry: Carbohydrates
Veterinary Pharmacology
Animal Growth and Development
Anaesthesiology
Gene Expression (incl. Microarray and other genome-wide approaches)
Neurosciences
Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
Paediatrics
Biologically Active Molecules
Nutrition and Dietetics
Separation Science
Agronomy
Medical and Health Sciences
Podiatry
Medical Infection Agents (incl. Prions)
Plant Physiology
Instrumental Methods (excl. Immunological and Bioassay Methods)
Veterinary Parasitology
Technology
Traditional Aboriginal and Torres Strait Islander Medicine and Treatments
Gastroenterology and Hepatology
Oncology and Carcinogenesis
Medicinal and Biomolecular Chemistry
Sports Medicine
Dermatology
Infectious Diseases
Medical Microbiology
Analytical Chemistry
Rheumatology and Arthritis
Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
Systems Physiology
Medical Biochemistry and Metabolomics
Tumour Immunology
Nutritional Physiology
Exploration Geochemistry
Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
Clinical Pharmacy and Pharmacy Practice
Cell Physiology
Crop and Pasture Biomass and Bioproducts
Pathology
Agricultural Land Management
Orthopaedics
Dental Therapeutics, Pharmacology and Toxicology
Analytical Spectrometry
Medical Biotechnology
Environmental and Occupational Health and Safety
Veterinary Medicine
Crop and Pasture Production
Organometallic Chemistry
Veterinary Microbiology (excl. Virology)
Agricultural Biotechnology Diagnostics (incl. Biosensors)
Neurology and Neuromuscular Diseases
Otorhinolaryngology
Pharmacogenomics
Crop and Pasture Improvement (Selection and Breeding)
Cancer Cell Biology
Complementary and Alternative Medicine
Genetics
Human Movement and Sports Science
Biochemistry and Cell Biology
Health Promotion

Research Impact

Health
Respiratory System and Diseases (incl. Asthma)
Skeletal System and Disorders (incl. Arthritis)
Cardiovascular System and Diseases
Diagnostic Methods
Skin and Related Disorders
Preventive Medicine
Infectious Diseases
Diabetes
Health Related to Ageing
Clinical Health (Organs, Diseases and Abnormal Conditions)
Beef Cattle
Cancer and Related Disorders
Substance Abuse
Fisheries - Aquaculture
Environmental Health
Plant Production and Plant Primary Products
Neurodegenerative Disorders Related to Ageing
Blood Disorders
Public Health (excl. Specific Population Health)
Digestive System Disorders
Nervous System and Disorders
Allied Health Therapies (excl. Mental Health Services)
Health Status (e.g. Indicators of Well-Being)
Nutrition
Environmentally Sustainable Plant Production
Deer
Urogenital System and Disorders
Expanding Knowledge in Technology
Human Pharmaceutical Products
Pasture, Browse and Fodder Crops
Veterinary Biological Preventatives (e.g. Vaccines)
Poultry
Expanding Knowledge in the Biological Sciences
Health and Support Services
Child Health
Fresh Fruit and Vegetables (Post Harvest)
Rural Health
Pigs
Mineral Exploration
Sugar Cane (Cut for Crushing)
Evaluation of Health Outcomes
Hearing, Vision, Speech and Their Disorders
Plastic Products (incl. Construction Materials)
Scientific Instruments
Social Structure and Health
Vegetables
Surgical Methods and Procedures
Expanding Knowledge in the Medical and Health Sciences
Human Diagnostics
Health Education and Promotion

Career Best Publications

A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins; Journal of Pharmaceutical and Biomedical Analysis
Beta2-Agonist Doping Control and Optical Isomer Challenges; Sports Medicine: Reviews of Applied Medicine and Science in Sport and Exercise
Determination of Albuterol Enantiomers in Animal Tissue Matrices by LC-MS/MS: Application in Therapeutic Myoanabolic Studies; Chromatographia
Enantioselective disposition of (R/S)-albuterol in skeletal and cardiac muscle; Drug Testing and Analysis
Hypolipidaemic effect of crude extract from Carpobrotus rossii (pigface) in healthy rats; Food and Chemical Toxicology
Relationship between cotinine and trans-3' -hydroxycotinine glucuronidation and the nicotine metabolite ratio in Caucasian smokers; Biomarkers
SULT 1A3 single-nucleotide polymorphism and the single dose pharmacokinetics of inhaled salbutamol enantiomers: Are some athletes at risk of higher urine levels?; Drug testing and analysis

Research Publications

(R,S)-Salbutamol plasma concentrations in severe asthma; Journal of Clinical Pharmacy and Therapeutics
A low-volume microtitre plate assay for determination of the AFXa activity of enoxaparin; Out of the Wilderness Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium
A randomised trial of kunzea oil in comparison with amorolfine nail lacquer for the treatment of toenail onychomycosis; Australasian Pharmaceutical Science Association Annual Conference
A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins; Journal of Pharmaceutical and Biomedical Analysis
A syringe guard
ABC Australia Wide Story on beta2-agonist doping control
Albuterol enantiomer levels, lung function and QTc interval in patients with acute severe asthma and COPD in the emergency department; International Journal of Emergency Medicine (Online)
An evaluation of the clinical efficacy of kunzea oil formulations in the therapeuticmanagement of psoriasis in adults; Australasian Pharmaceutical Science Association Annual Conference
An examination of the essential oils of Tasmanian Kunzea ambigua, other Kunzea spp. and commercial kunzea oil; Journal of Essential Oil Research
An examination of the essential oils of Tasmanian Kunzea ambigua, other Kunzea spp. and commercial kunzea oil; APSA annual conference Aus-CRS symposium
Antioxidant activity of Carpobrotus rossii (pigface) extract; ASCEPT 2009
Antiplatelet activity of Carpobrotus rossii (pigface) extract; ASCEPT 2009
Application of an assay for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine for the assessment of tobacco-related harm; Journal of Pharmaceutical and Biomedical Analysis
Aspects of the Pharmacotherapay of Airways Disease
Barrett's oesophagus: pilot application of MudPIT proteomics to oesophageal tissue after proton pump inhibitor therapy; Australasian Pharmaceutical Science Association Conference
Beta2-Agonist Doping Control and Optical Isomer Challenges; Sports Medicine: Reviews of Applied Medicine and Science in Sport and Exercise
Bicycle injuries: road trauma is not the only concern; Australian and New Zealand Journal of Public Health
Bike Injuries
Bike Injuries
Bike injuries
Bike safety leaflet for young riders
Biological monitoring of low level occupational xylene exposure and the role of recent exposure; Annals of Occupational Hygiene
Characterisation and evaluation of the in vitro antimicrobial activity of Kunzea ambigua essential oil; Medicines design to delivery
Chemical content and antioxidant activity of Carpobrotus rossii, C. edulis and C. aequilaterus; Medicines design to delivery
Childhood Injuries
Comparison of methods for the determination of total selenium in plasma by magnetic sector inductively coupled plasma mass spectrometry; Analytica Chimica Acta
Dangers of roller blading
Determination of Albuterol Enantiomers in Animal Tissue Matrices by LC-MS/MS: Application in Therapeutic Myoanabolic Studies; Chromatographia
Determination of ceftiofur in bovine plasma by HPLC-DAD; Journal of Pharmaceutical and Biomedical Analysis
Determination of cotinine, 3'-hydroxycotinine, and their glucuronides in urine by ultra-high performance liquid chromatography; Analytical Letters
Determination of nicotine in cartridge-based electronic cigarettes; Analytical Letters
Determination of pergolide in horse plasma by UPLC–MS/MS for pharmacokinetic applications; Journal of Pharmaceutical and Biomedical Analysis
Ecophysiology of Carpobrotus rossii in Tasmania: Linking plant's antioxidant activity with a natural habitat; Ecological Questions
Effect of blueberry tea on improving metabolic and vascular function in people with and without type 2 diabetes - A Pilot Study; Australian Diabetes Society and the Australian Diabetes Educators Association Annual Scientific Meeting 2016
Effect of celecoxib on cyclooxygenase-2 expression and possible variants in a patient with Barrett's esophagus; Diseases of the Esophagus
Effect of chronic Carpobrotus rossii (pigface) ingestion on systolic blood pressure, body weight, blood lipids, haematological profile and in vitro vascular function in adult male rats; ASCEPT '10
Effective reversed-phase ion pair high-performance liquid chromatography method for the separation and characterization of intact low-molecular-weight heparins ; Analytical Biochemistry
Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells; Australian Neuroscience Society Annual Meeting
Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells; APSN 2012
Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice; PLoS One
Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice; Australian Neuroscience Society 31st Annual Meeting
Elevated plasma glutathione peroxidase concentration in acute severe asthma: Comparison with plasma glutathione peroxidase activity, selenium and malondialdehyde; Scandinavian Journal of Clinical and Laboratory Investigation
Elevated plasma glutathione peroxidase concentration in rheumatoid arthritis; Medicines design to delivery
Enantioselective bronchopulmonary pharmacokinetics of salbutamol in horses; 2016 ACVIM Forum
Enantioselective disposition of (R)-salmeterol and (S)-salmeterol in urine following inhaled dosing and application to doping control; Drug Testing and Analysis
Enantioselective disposition of (R/S)-albuterol in skeletal and cardiac muscle; Drug Testing and Analysis
Enantioselective distribution of (R/S)-salbutamol in skeletal muscle in a spinal muscular atrophy mouse model; Medicines design to delivery
Enhanced stability of sulfamethoxazole and trimethoprim against oxidation using hydroxypropyl-B-cyclodextrin; Pharmazie
Evaluation of a covered-rod silicone implant containing ivermectin for long-term prevention of heartworm infection in dogs; American Journal of Veterinary Research
Evaluation of repellent properties of volatile extracts from the Australian native plant Kunzea ambigua against Aedes aegypti (Diptera: Culcidae); Journal of Medical Entomology
Eye injuries
Eye injuries
Fatal Injuries in Tasmania from 1991 to 1994
Genetic variations at activator protein-1 among patients with steroid-insensitive asthma; Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium Hobart
Glucose tolerance is improved by supplementation with carpobrotus rossii flavanoids in insulin resistant mice; Thirty-Eighth Annual Scientific Meeting of The Nutrition Society of Australia
Guest Blog: WADA turns to Tasmania in anti-doping efforts
High-dose beta2-agonist treatment is associated with cardiac dysfunction in chronic obstructive pulmonary disease
High-performance liquid chromatographic assay for the simultaneous determination of ipratropium bromide, fenoterol, salbutamol and terbutaline in nebulizer solution; Journal of Pharmaceutical and Biomedical Analysis
Hypolipidaemic effect of crude extract from Carpobrotus rossii (pigface) in healthy rats; Food and Chemical Toxicology
Identifying novel markers of late onset neonatal sepsis using proteomic analysis; The 20th Annual Congress of the Perinatal Society of Australia and New Zealand
In vitro antioxidant, antiplatelet and anti-inflammatory activity of Carpobrotus rossii (pigface) extract; Journal of Ethnopharmacology
In vitro stability of enoxaparin solutions (20 mg/mL) diluted in 4% glucose; Clinical Therapeutics
Increased selenium concentrations in seronorm trace elements serum; Clinical Chemistry
Investigation of amyloid plaques and enoxaparin brain penetration using Raman and infrared spectroscopy; 2015 Joint APSA-ASCEPT Annual Conference
Investigation of freezing- and thawing-induced biological, chemical, and physical changes to enoxaparin solution; Journal of Pharmaceutical Science
Investigation of salbutamol enantiomer deposition in epithelial lining fluid in horses; APSA-ASCEPT Joint Scientific Meeting 2015
Investigation of the effect of heating on the chemistry and antifactor Xa activity of enoxaparin; Journal of Pharmaceutical Science
Investigation of urinary levels of salbutamol in asthmatic patients receiving inhaled therapy; Journal of Clinical Pharmacy and Therapeutics
Is the essential oil from the Australian native plant Kunzea ambigua repellent to mosquitoes?; Medicines design to delivery
LC-MS method for the determination of albuterol enantiomers in human plasma using manual solid-phase extraction and a non-deuterated internal standard; Journal of Pharmaceutical and Biomedical Analysis
Modulation of flavonoid and tannin production of Carpobrotus rossii by environmental conditions; Environmental and Experimental Botany
Montelukast pharmacogenetics in a clinical setting as an adjunct therapy among patients using corticosteroids; Medicines design to delivery
Most bike injuries 'off public roads'
Netball most dangerous sport for females
Peripheral treatment with enoxaparin exacerbates amyloid plaque pathology in Tg2576 mice; Journal of Neuroscience Research
Pharmacokinetics of intravenous continuous rate infusions of sodium benzylpenicillin 2 and ceftiofur sodium in adult horses; American Journal of Veterinary Research
Plasma glutathione peroxidase (GSH-Px) concentration is elevated in rheumatoid arthritis: a case–control study; Clinical Rheumatology
Plasma glutathione peroxidase by ELISA and relationship to selenium level; Clinica Chimica Acta
Prescribing trends for anti-asthma drugs in Tasmania following the National Asthma Campaign; Journal of Clinical Pharmacy and Therapeutics
Proteoglycans in the central nervous system: Role in development, neural repair, and Alzheimer's disease; IUBMB Life
Protoanemonin content variation between Clematis spp.: Leaf, Stem and Root; Natural Product Communications
Psychoactive drug prescribing in the Tasmanian community; Medical Journal of Australia
Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil; Veterinary Record
Ranunculin the antibacterial constituent in Clematis aristata, and its mode of action; Proceedings of APSA
Relationship between clinical site of isolation and ability to form biofilms in vitro in nontypeable Haemophilus influenzae; Canadian Journal of Microbiology
Relationship between cotinine and trans-3' -hydroxycotinine glucuronidation and the nicotine metabolite ratio in Caucasian smokers; Biomarkers
Reliability of Haemophilus influenzae biofilm measurement via static method, and determinants of in vitro biofilm production; Canadian Journal of Microbiology
Roads and guns most lethal risks
Safety and efficacy of kunzea oil-containing formulations for the management of psoriasis: A randomized, controlled trial; Journal of Clinical Pharmacy and Therapeutics
Saliva treatment of Dodoneae viscosa increases its antibacterial activity; Australasian Pharmaceutical Science Association Conference
Selenium status in Southern Tasmania; European Journal of Clinical Nutrition
Selenoprotein P analysis in human plasma - A discrepancy between HPLC fractionation of human plasma with heparin-affinity chromatography and SDS-PAGE with immunoblot analysis; Biological Trace Element Research
Separation and characterisation of different low-molecular-weight heparins by reversed-phase ion-interaction high-performance liquid chromatography; Medicines design to delivery
Serum salbutamol enantiomer levels and extra pulmonary effects during disease exacerbation of COPD; Australasian Pharmaceutical Science Association Annual Conference
Size and sulfation are critical for the effect of heparin on APP processing and A beta production; Journal of Neurochemistry
Stability of ipratropium bromide and salbutamol nebuliser admixtures; International Journal of Pharmacy Practice
Studies of chemical modification and formation of colon targeted microparticulates of Pachyman; Out of the Wilderness Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium
Studies on the potential anticancer compounds of Tasmanian Clematis species; Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium Hobart
SULT 1A3 single-nucleotide polymorphism and the single dose pharmacokinetics of inhaled salbutamol enantiomers: Are some athletes at risk of higher urine levels?; Drug testing and analysis
SULT1A3 Single Nucleotide Polymorphisms (SNPs) and their effect on Salbutamol Enantiomer Pharmacokinetics; Medicines design to delivery
T.I.S.P.P. RISK
T.I.S.P.P. RISK
Tasmanian injury and prevention project
Tasmanian researchers scrutinise athletes' use of asthma treatment as performance enhancer
Terbutaline: level the playing field for inhaled β2-agonists by introducing a dosing and urine threshold; British Journal of Sports Medicine
The chemistry and pharmaceutical potential of Callitris spp. from Tasmania; Australasian Pharmaceutical Science Association Conference
The Determination of Selenium in Human Plasma by Magnetic Sector ICP-MS; Interact 2004
The effect of heating on the chemistry and biological activity of enoxaparin; Medicines design to delivery
The effect of varenicline and nicotine patch on smoking rate and satisfaction with smoking: an examination of the mechanism of action of two pre-quit pharmacotherapies; Psychopharmacology
The effects of freezing and thawing on the AFXa activity of enoxaparin solution; Medicines design to delivery
The screening of chemical constituents, antitumour and antimicrobial activities of Tasmanian clematis species; Australasian Pharmaceutical Science Association Conference
TISPP - eye injuries
TISPP Risk
Toenail onychomycosis: an important global disease burden; Journal of Clinical Pharmacy and Therapeutics
Treatment of pastern dermatitis with a formulation containing kunzea oil' a randomised controlled trail; Annual Conference of Australasian Pharmaceutical Science Association - Medicines design to delivery
Volatile organic compounds in runners near a roadway: increased blood levels after short-duration exercise; British Journal of Sports Medicine
World Anti-Doping Agency’s drug war comes to Tasmania
Zebrafish - on the move towards ophthalmological research; Eye

Research Projects

A Randomised Trial of Kunzea Oil in Comparison with Amorofline 5% Solution Nail Lacquer for the Treatment of Dermatophytic Toenail Onychomycoses; Rural Industries Research & Development Corporation (RIRDC)
Analysis of the Essential Oil of Kunzea Ambigua and Screening Formulation for Antibacterial and Antifungal Activities; Armstrong Pharmacy (ARMPH)
Business Competition Grant - School of Pharmacy; University of Tasmania (UTAS)
Cancer Prevention in Barrett's Oesophagus: Celecoxib and In Vivo Assessment of COX-2 Expression in Metaplastic and Dysplastic Oesophageal Epithelium; Royal Hobart Hospital Research Foundation (RHHRF)
Development of a Simple and Effective Ion-chromatagraphic Analysis for the Separation and Identification of Non-anticoagulant fractions of Enoxaparin; University of Tasmania (UTAS)
Drug Discovery, Biotechnology and Bridging the Gap using an Intermediary: Pilot Application to Novel Flavonoids with Potential to Reduce Cardiovascular Disease Risk; University of Tasmania (UTAS)
Effect of Thompson's Cholesterol Manager on Type 2 Diabetes; Tasmanian Community Fund (TasCF)
Enantioselective pharmacokinetics of formoterol and application to doping control; World Anti-Doping Agency (WAA)
Enantioselective pharmacokinetics of salbutamol and application to doping control; World Anti-Doping Agency (WAA)
Hyphenated Capillary Electrophoresis-Mass Spectrometer Facility; Australian Research Council (ARC)
Identifying Novel Markers of Neonatal Sepsis; Royal Hobart Hospital Research Foundation (RHHRF)
Investigations of the Chemical and Physical Stability of Iron Polymaltose Intravenous Infusion; Royal Hobart Hospital Research Foundation (RHHRF)
Pharmacoproteomic Investigation of Barrett's Oesophagus and Proton Pump Inhibitor Therapy; Royal Hobart Hospital Research Foundation (RHHRF)
Pilot Study of Gene Expression & Protein Regulation in Barrett's Oesophagus and Oesophageal Adenocarcinoma; Clifford Craig Foundation (CCFoundation)
Purchase of a new generation fast mapping Raman system; Australian Research Council (ARC)
Purchase of an ultra-performance liquid chromatograph-triple quadrupole mass spectrometer; Australian Research Council (ARC)
Risk Factors for Upper Limb Fractures in Adolescence; National Health & Medical Research Council (NHMRC)
Risk Factors for Upper Limb Fractures in Adolescence; Clifford Craig Medical Research Trust/UTAS (CCMRT/UTAS)
Stereoselective Metabolism of Salbutamol as a Determinant of the Response in Acute Asthma; Royal Hobart Hospital Research Foundation (RHHRF)
Tasmania: a selenium-deficient state?; University of Tasmania (UTAS)
Tasmania: A Selenium-deficient State? A Population-based Assessment of Selenium Status; Royal Hobart Hospital Research Foundation (RHHRF)
The Potential Role of Human Papilloma Virus in Short and Long Segment Barrett's Oesophagus and the Development of Dysplasia; Clifford Craig Foundation (CCFoundation)
Zebrafish: Pilot Applications in Muscle and Angiogenesis; University of Tasmania (UTAS)
Ceftiofur analysis in bovine serum
Chemika impurity characterisation - ICH guidelines
Deslorelin implant analysis: effect of e-beam sterilisation
Deslorelin implant analysis: used implants #2
Deslorelin in plasma by LC-MS: methos development
Donation - Asthma Foundation of Tasmania PhD Scholarship for Kwang Choon Yee
Enantioselective salbutamol analysis in blood of COPD patients
Medication stability in the Pacific Islands
Microsporum screening of algal extract formulation
Quantitative analysis of R-Salbutamol in feed samples
Quantitative analysis of R-Salbutamol in pig muscle and liver: supplementation trial
R, S-Salbutamol in chicken feed pellets
R-Salbutamol dissolution from fish feed pellets
Salbutamol Enantiomers in Delta-7 Mouse Plasma, Muscle and Brain- PK Range Study
Walter and Eliza Hall Fungal Screening Project

Research Candidate Supervision

Application of Raman Spectroscopy to the Evaluation of Biofilm Formation and Virulence of Pathogenic Microorganisms
Develop and validate zebrafish cardiac and muscle physiology models of beta2 agonist effects and pharmacokinetics
Drug Quality Assurance "Stability of Drugs Under Extreme Environmental Conditions"
Effect of Agmatine in a Mouse Model of Mitochondrial Optic Neuropathy.
Enoxaparin- Physicochemical Investigations into the Effects of Freezing and Heating
Extraction, Analysis, and Biological Screening of Callitris Species Essential Oils
Factors Influencing the Performance and Documentation of Clinical Interventions by Australian Community Pharmacists
Investigation of Chemical Components and Pharmaceutical Potential of Carpobrotus Species
Kunzea Oil- Investigation of Composition, Bioactivity and Therapeutic Potential
Pharmacogenetics and Chiral Aspects of Anti-Asthma Therapy
Studies on the Use of Glycosaminoglycans for the Treatment of Alzheimer's Disease
The Pharmaceutical and Nutraceutical Potential of the Halophytic Plant Carpobrotus rossii
The Pharmaceutical Potential of Compounds from Tasmanian Clematis Species
The Role of Mitochondria in the Visual Function of Zebrafish (Danio. rerio)
The Safety and Efficacy of Electronic-Cigarettes as Cessation Aids and the use of Electronic-Cigarettes by Smokers.