Web Access Research Portal

Researcher: Ghanem, A (Dr Ashraf Ghanem)

Fields of Research

Separation Science
Organic Green Chemistry
Organic Chemical Synthesis
Colloid and Surface Chemistry
Organic Chemistry
Free Radical Chemistry
Theoretical and Computational Chemistry
Electroanalytical Chemistry
Enzymes

Research Objectives

Expanding Knowledge in the Chemical Sciences
Environmentally Sustainable Manufacturing
Human Pharmaceutical Products
Technological and Organisational Innovation
Pulp and Paper
Organic Industrial Chemicals (excl. Resins, Rubber and Plastics)
Manufacturing Standards and Calibrations
Construction Processes
Industrial Instruments
Scientific Instruments

Career Best Publications

Application and comparison of immobilized and coated amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phases for the enantioselective separation of -blockers enantiomers by liquid chromatography; Talanta
Asymmetric Cyclopropanation of Olefins with an in situ Generated; Synlett
Asymmetric cyclopropanations and cycloadditions of dioxocarbenes; Synthesis
Enantiomeric separation of cyclopropane derivatives on a polysaccharide-based chiral stationary phase; Analytica Chimica Acta
First x-ray structure of a N-naphthaloyl tethered chiral dirhodium(II) complex: structural basis for tether substitution improving asymmetric control in olefin cyclopropanation; Chemistry - A European journal
Immobilized versus coated amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phases for the enantioselective separation of cyclopropane derivatives by liquid chromatography; The Journal of Chromatography A
Lipase-catalyzed kinetic resolution of racemates: A versatile method for the separation of enantiomers; Enantiomer Separation Fundamentals and Practical Methods
Lipase-mediated enantioselective kinetic resolution of racemic acidic drugs in non-standard organic solvents: Direct chiral liquid chromatography monitoring and accurate determination of the enantiomeric excesses; The Journal of Chromatography A
On the solvent versatility in immobilized amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phase in high performance liquid chromatography: Application to the asymmetric cyclopropanation of olefins; Analytica Chimica Acta
Rh(II)-Catalyzed Enantioselective Cyclopropanation of Olefins with Dimethyl Malonate via in Situ Generated Phenyliodonium Ylide; Organic Letters
Rhodium(II)-Catalyzed Inter- and Intramolecular Cyclopropanations with Diazo Compounds and Phenyliodonium Ylides: Synthesis and Chiral Analysis; Helvetica Chimica Acta
The utility of cyclodextrins in lipase-catalyzed transesterification in organic solvents: enhanced reaction rate and enantioselectivity; Organic and Biomolecular Chemistry
Trends in lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds; Tetrahedron
True and false reversal of the elution order of barbiturates on a bonded cellulose-based chiral stationary phase; Journal of Chromatography A

Research Publications

Application and comparison of immobilized and coated amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phases for the enantioselective separation of -blockers enantiomers by liquid chromatography; Talanta
Application of lipases in kinetic resolution of racemates; Chirality
Asymmetric Cyclopropanation of Olefins with an in situ Generated; Synlett
Asymmetric cyclopropanations and cycloadditions of dioxocarbenes; Synthesis
Asymmetric hydrogenation of an ,-unsaturated ketone by diamine(ether-phosphine)ruthenium(II) complexes and lipase-catalyzed kinetic resolution: a consecutive approach; Tetrahedron: Asymmetry
C11-Chirasil-Dex as chiral stationary phase in GC: enantioselective separation of cyclopropane derivatives; Talanta
Chiral recognition ability and solvent versatility of bonded amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phase: Enantioselective liquid chromatographic resolution of racemic N-alkylated barbiturates and thalidomide analogs; Chirality
Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC; Talanta
Chirasil--dex with a new C11-spacer for enantioselective gas chromatography. Application to the kinetic resolution of secondary alcohols catalyzed by lipase; Chromatographia
Comparison, applications, advantages, and limitations of immobilized and coated amylose tris-(3,5-Dimethylphenylcarbamate) chiral stationary phases in HPLC; Journal of Liquid Chromatography and Related Technologies
Determination of Vardenafil in pharmaceutical formulation by HPLC using conventional C18 and monolithic silica columns; Journal of Liquid Chromatography and Related Technologies
Diazo Compounds and Phenyliodonium Ylides in Inter- and Intramolecular Cyclopropanations Catalyzed by Dirhodium(II). Synthesis and Chiral Resolution by GC versus HPLC; Monatshefte fr Chemie / Chemical Monthly
Direct Enantioselective HPLC Monitoring of Lipase-Catalyzed Kinetic Resolution of 2-Phenoxy Propionic Acid in Non-Standard Organic Solvents; Chromatographia
Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of flurbiprofen; Chirality
Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of tiaprofenic acid in nonstandard HPLC organic solvents; Chirality
Enantiomeric separation of cyclopropane derivatives on a polysaccharide-based chiral stationary phase; Analytica Chimica Acta
Enantioselective gas chromatographic analysis of cyclopropane derivatives; Chromatographia
Enantioselective Gas Chromatographic Separation of Racemic N-alkylated Barbiturates: Application of C11-Chirasil-Dex as Chiral Stationary Phase in GC; Analytical Chemistry Insights
Enantioselective Toxicity and Carcinogenesis; Current Pharmaceutical Analysis
Entrapment of Pseudomonas cepacia lipase with peracetylated β-cyclodextrin in sol-gel: application to the kinetic resolution of secondary alcohols ; Tetrahedron: Asymmetry
Exploring solvent versatility in immobilized cellulose-based chiral stationary phase for the enantioselective liquid chromatographic resolution of racemates; Journal of Separation Science
First x-ray structure of a N-naphthaloyl tethered chiral dirhodium(II) complex: structural basis for tether substitution improving asymmetric control in olefin cyclopropanation; Chemistry - A European journal
Immobilized versus coated amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phases for the enantioselective separation of cyclopropane derivatives by liquid chromatography; The Journal of Chromatography A
Lipase in Organic Synthesis; Encyclopaedia of Reagents in Organic Synthesis
Lipase-catalyzed access to enantiomerically pure (R)- and (S)-trans-4-phenyl-3-butene-2-ol ; Tetrahedron: Asymmetry
Lipase-catalyzed irreversible transesterification of 1-(2-furyl)ethanol using isopropenyl acetate; Chirality
Lipase-catalyzed Irreversible Transesterification of Secondary Alcohols Using Isopropenyl Acetate; Monatshefte fr Chemie / Chemical Monthly
Lipase-catalyzed kinetic resolution of racemates: A versatile method for the separation of enantiomers; Enantiomer Separation Fundamentals and Practical Methods
Lipase-mediated chiral resolution of racemates in organic solvents; Tetrahedron: Asymmetry
Lipase-mediated enantioselective kinetic resolution of racemic acidic drugs in non-standard organic solvents: Direct chiral liquid chromatography monitoring and accurate determination of the enantiomeric excesses; The Journal of Chromatography A
On the solvent versatility in immobilized amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phase in high performance liquid chromatography: Application to the asymmetric cyclopropanation of olefins; Analytica Chimica Acta
One-pot synthesis and chiral analysis of cyclopropane derivatives; Chirality
Peracetylated -cyclodextrin as additive in enzymatic reactions: enhanced reaction rate and enantiomeric ratio in lipase-catalyzed transesterifications in organic solvents; Tetrahedron: Asymmetry
Reversed Phase Liquid Chromatographic Method for the High-Throughput Analysis of Clopidogrel in Pharmaceutical Formulations Using a Monolithic Silica Column; Journal of Liquid Chromatography and Related Technologies
Rh(II)-Catalyzed Enantioselective Cyclopropanation of Olefins with Dimethyl Malonate via in Situ Generated Phenyliodonium Ylide; Organic Letters
Rhodium(II)-Catalyzed Inter- and Intramolecular Cyclopropanations with Diazo Compounds and Phenyliodonium Ylides: Synthesis and Chiral Analysis; Helvetica Chimica Acta
Separation and sample pre-treatment in bioanalysis using monolithic phases: A review; Analytica Chimica Acta
Solvent versatility of immobilized amylase and cellulose-based chiral stationary phases in enantioselective LC separation and monitoring of bio-catalyzed resolutions of acidic drugs in non-standard organic solvents; Chromatographia
The utility of cyclodextrins in lipase-catalyzed transesterification in organic solvents: enhanced reaction rate and enantioselectivity; Organic and Biomolecular Chemistry
Trends in lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds; Tetrahedron
True and false reversal of the elution order of barbiturates on a bonded cellulose-based chiral stationary phase; Journal of Chromatography A
What's New in Chromatographic Enantioseparations; Current Analytical Chemistry

Research Projects

Research Candidate Supervision