Web Access Research Portal

Researcher: Horne, HJ (Dr James Horne)

Fields of Research

Structural Biology (incl. Macromolecular Modelling)
Pharmaceutical Sciences
Industrial Chemistry
Characterisation of Biological Macromolecules
Cell Metabolism
Primary Health Care
Natural Products Chemistry
Plant Physiology
Cardiology (incl. Cardiovascular Diseases)
Biologically Active Molecules
Transition Metal Chemistry
Organic Chemical Synthesis
Medical Biochemistry and Metabolomics
Synthesis of Materials
Medical Bacteriology
Fish Pests and Diseases
Analytical Spectrometry
Animal Nutrition

Research Objectives

Expanding Knowledge in the Chemical Sciences
Expanding Knowledge in the Biological Sciences
Public Health (excl. Specific Population Health)
Infectious Diseases
Cardiovascular System and Diseases
Expanding Knowledge in the Medical and Health Sciences
Aquaculture Fin Fish (excl. Tuna)
Expanding Knowledge in the Environmental Sciences
Human Pharmaceutical Products
Neurodegenerative Disorders Related to Ageing
Paper Products (incl. Coated Paper)
Pulp and Paper
Prepared Animal Feed

Career Best Publications

Research Publications

ent-Labdane Diterpenoids from Dodonaea viscosa; Journal of Natural Products
In-vitro suppression of IL-6 and IL-8 release from human pulmonary epithelial cells by non-anticoagulant fraction of enoxaparin; PLoS One
Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA; Angewandte Chemie
Biosynthesis of the halogenated auxin, 4-chloroindole-3-acetic acid; Plant Physiology
Characterization of the N-Methyltransferase Activities of the Multifunctional Polypeptide Cyclosporin Synthetase ; Chemistry and Biology
Examination of the role of intestinal fatty acid-binding protein in drug absorption using a parallel artificial membrane permeability assay; Chemistry and Biology
High Glass Transition Temperature Fluoropolymers for Hydrophobic Surface Coatings via RAFT Copolymerization; Australian Journal of Chemistry
Isolation and characterization of 1β-Acetoxypolygodial from Tasmannia Lanceolata; Asian Journal of Organic Chemistry
Metabolomics reveals increased isoleukotoxin diol (12,13-DHOME) in human plasma after acute Intralipid infusion; Journal of Lipid Research
Non-anticoagulant fractions of enoxaparin suppress inflammatory cytokine release from peripheral blood mononuclear cells of allergic asthmatic individuals; PLoS One
Probing the fibrate binding specificity of rat liver fatty acid binding protein; Journal of Medicinal Chemistry
Serum metabolic profile predicts adverse central haemodynamics in patients with type 2 diabetes mellitus; Acta Diabetologica
Structural and Biochemical Characterization of the Oxidoreductase NmDsbA3 from Neisseria meningitidis; Journal of Biological Chemistry
Synthesis of guar gum-graft-poly (acrylamide-co-diallyldimethylammonium chloride) and its application in the pulp and paper industry; BioResources
The metabolomics of alpha-synuclein (SNCA) gene deletion and mutation in mouse brain; Metabolomics
The structural impact of a polyglutamine tract is location dependent; Biophysical Journal
The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes; Journal of Biological Chemistry
Unraveling the mechanism of polymerisation with the Phillips catalyst; Organometallics
Using NMR and SEM, to study the behaviour of pitch; 64th Appita

Research Projects

Chemical and physical changes in fish feed
Chemika impurity characterisation - ICH guidelines

Research Candidate Supervision