Web Access Research Portal

Researcher: Edwards, LM (Dr Lindsay Edwards)

Fields of Research

Systems physiology
Exercise physiology
Cardiology (incl. cardiovascular diseases)
Animal physiology - systems
Biomechanics
Pharmacology and pharmaceutical sciences
Medical biochemistry and metabolomics
Nutritional science
Clinical chemistry (incl. diagnostics)
Genetics
Paramedicine
Zoology
Neurology and neuromuscular diseases
Medical biochemistry - lipids
Radiology and organ imaging
Cell metabolism
Metabolic medicine
Basic pharmacology
Peripheral nervous system
Cardiovascular medicine and haematology
Medical biochemistry - proteins and peptides (incl. medical proteomics)
Cell physiology
Animal physiology - biophysics
Motor control
Bioinformatic methods development
Medical biotechnology

Research Objectives

Expanding knowledge in the health sciences
Clinical health
Diagnosis of human diseases and conditions
Expanding knowledge in the biological sciences
Defence
Evaluation of health and support services

Career Best Publications

Research Publications

A comparison of visual and quantitative assessment of left ventricular ejection fraction by cardiac magnetic resonance; International Journal of Cardiovascular Imaging
A genetic disease in humans demonstrates the importance of hypoxia-inducible factor in skeletal muscle metabolism; The Federation of American Societies of Experimental Biology
A glimpse of genius
A short-term high fat diet impairs cardiac high energy phosphate metabolism, exercise capacity and cognitive function; Circulation
Angiotensin-converting enzyme genotype and successful ascent to extreme high altitude; High Altitude Medicine and Biology
Arterial blood gases and oxygen content in climbers on Mount Everest; New England Journal of Medicine
Caudwell Xtreme Everest expedition; High Altitude Medicine and Biology
Caudwell Xtreme Everest: a field study of human adaptation to hypoxia; Critical Care
Changes in skeletal muscle oxygenation during exercise measured by near-infrared spectroscopy on ascent to altitude; Critical Care
Critical role of complex III in the early metabolic changes following myocardial infarction; Cardiovascular Research
Crunch match
Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia; BMC Medical Research Methodology
Effects of downstream drug metabolites of spironolactone on aortic stiffness and ambulatory blood pressure; 24th Scientific Meeting of the International Society of Hypertension
Empower yourself
Erratum to: A comparison of visual and quantitative assessment of left ventricular ejection fraction by cardiac magnetic resonance; International Journal of Cardiovascular Imaging
Fitness myths exposed
High-fat feeding increases fatty acid oxidation rates and uncouples respiration in cardiac mitochondria; Cardiovascular Drugs and Therapy
In silico studies on the sensitivity of myocardial PCr/ATP to changes in mitochondrial enzyme activity and oxygen concentration; Molecular Biosystems
Integrating muscle cell biochemistry and whole-body physiology in humans: 31P-MRS data from the InSight trial; Scientific Reports
Invited review: Mitochondria in heart failure; Current Opinion in Clinical Nutrition and Metabolic Care
Is exercise efficiency really impaired in heart failure patients?; The European Journal of Heart Failure
Minding your 'p's and 'H's
Paramedic accuracy in identifying the anatomical landmarks for needle chest decompression; Australian College of Ambulance Professionals National Conference
Regulation of human metabolism by hypoxia-inducible factor; National Academy of Sciences of The United States of America. Proceedings
Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men; FASEB Journal
Spironolactone reduces aortic stiffness in people with a hypertensive response to exercise via the blood pressure dependent effects of canrenoate; 12th meeting of the Association for Research into Arterial Structure and Physiology
The effect of crank inertial load on the physiological and biomechanical responses of trained cyclists; Journal of Sports Sciences
The effect of high-altitude on human skeletal muscle energetics: 31P-MRS results from the Caudwell Xtreme Everest expedition; PLoS One
The effects of training on gross efficiency in cycling: A review; International Journal of Sports Medicine
The metabolomics of alpha-synuclein (SNCA) gene deletion and mutation in mouse brain; Metabolomics
Uncoupling protein-3 inversely correlates with resting metabolic rate in fit, young men; Physiological Society
Whole-body efficiency is negatively correlated with minimum torque per duty cycle in trained cyclists; Journal of Sports Sciences

Research Projects

Multidimensional analysis of biomarkers for the early detection of Alzheimer's disease using in vivo MRS; The Mason Foundation (ANZCT-Mason Fdn)
Using engineered tissue and magnetic resonance spectroscopy to investigate human muscle function and metabolism; The MAWA Trust (MAWA)

Research Candidate Supervision

Cardiovascular Abnormalities Associated With High Blood Pressure