Web Access Research Portal

Researcher: Kunde, DA (Dr Dale Kunde)

Research Fields

Basic Pharmacology
Nephrology and Urology
Medical Bacteriology
Medical Biochemistry: Nucleic Acids
Haematology
Genetic Immunology
Infectious Diseases
Analytical Chemistry
Nutrition and Dietetics
Immunology
Cell Development, Proliferation and Death
Respiratory Diseases
Central Nervous System
Clinical Chemistry (diagnostics)
Animal Physiology - Systems
Pharmacology and Pharmaceutical Sciences
Phycology (incl. Marine Grasses)
Clinical Pharmacology and Therapeutics
Veterinary Microbiology (excl. Virology)
Medical Biochemistry: Lipids
Complementary and Alternative Medicine
Agricultural Biotechnology Diagnostics (incl. Biosensors)
Clinical Microbiology
Innate Immunity
Specialist Studies in Education
Preventive Medicine
Cellular Immunology
Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
Community Child Health
Optometry and Ophthalmology
Cancer Cell Biology
Toxicology (incl. Clinical Toxicology)
Geriatrics and Gerontology
Health and Community Services
Allergy
Epigenetics (incl. Genome Methylation and Epigenomics)
Cell Neurochemistry
Tumour Immunology
Gastroenterology and Hepatology

Research Impact

Urogenital System and Disorders
Blood Disorders
Infectious Diseases
Diagnostic Methods
Immune System and Allergy
Digestive System Disorders
Respiratory System and Diseases (incl. Asthma)
Cardiovascular System and Diseases
Nutrition
Nervous System and Disorders
Inherited Diseases (incl. Gene Therapy)
Fisheries - Aquaculture
Education and Training Systems
Expanding Knowledge in the Environmental Sciences
Health
Preventive Medicine
Sheep - Meat
Disease Distribution and Transmission (incl. Surveillance and Response)
Sheep - Wool
Beef Cattle
Neurodegenerative Disorders Related to Ageing
Clinical Health (Organs, Diseases and Abnormal Conditions)
Health Related to Ageing
Social Structure and Health

Career Best Publications

Expression of transient receptor potential vanilloid 1 (TRPV1) and 2 (TRPV2) in human peripheral blood; Molecular Immunology
Tachykinin (NK1, NK2 and NK3) receptor, transient receptor potential vanilloid 1 (TRPV1) and early transcription factor, cFOS, mRNA expression in rat tissues following systemic capsaicin treatment; Regulatory Peptides

Research Publications

Haemophilus haemolyticus is infrequently misidentified as Haemophilus influenzae in diagnostic specimens in Australia; Diagnostic Microbiology and Infectious Disease
Acquired macrolide resistance genes in Haemophilus influenzae?; Journal of Antimicrobial Chemotherapy
An evaluation of SNP-based PCR methods for the detection of -lactamase-negative ampicillin-resistant Haemophilus influenzae; Journal of Infection and Chemotherapy
An improved screening test for increased urinary 5-hydroxyindole-3-acetic acid (5-HIAA) excretion; 36th Annual Scientific Conference of the Australasian Association of Clinical Biochemists
Antioxidants - the hot topic: the effect on DNA oxidation of chilli supplementation and in vitro capsaicin treatment; AIMS/AACB 2006
Bitter melon protects against ER stress in LS174T colonic epithelial cells; Bmc Alternative Medicine
Book review - HPLC of Proteins, Peptides and Polynucleotides: Contemporary Topics and Applications by MTW Hearn; Australian Journal of Medical Science
Capsaicin-induced death of human haematological malignant cell lines is independent of TRPV1 activation; Pharmacology
Characterisation of colonic dysplasia-like epithelial atypia in murine colitis; World journal of gastroenterology
Differential expression of TRPV1 on circulating PBMC sub-populations assessed by confocal microscopy; APSA-ASCEPT Joint Scientific Meeting 2015
Effect of epithelial cell type on in vitro invasion of non-typeable Haemophilus influenzae; Journal of microbiological methods
Effect of systemic vanilloids on TRPV1, substance P and tachykinin (NK1) receptors in the rat lumbosacral spinal cord and urinary bladder ; Australian Health and Medical Research Congress 2006
Effects of capsaicin, dihydrocapsaicin and curcumin on copper-induced oxidation of human serum lipids; Journal of Agricultural and Food Chemistry
Effects of capsaicinoids and curcumin on copper-induced oxidation of human serum; AIMS/AACB 2006
Effects of olive oil and tomato lycopene combination on heart disease risk factors; Asia Pacific Journal of Clinical Nutrition
Effects of Systemic Capsaicin Treatment on TRPV1 and Tachykinin NK1 Receptor Distribution and Function in the Nucleus of the Solitary Tract of the Adult Rat; Pharmacology
Ex vivo and in vitro actions of chilli and capsaicin on DNA Oxidation; Joint Meeting of ASCEPT and APSA
Expression of transient receptor potential vanilloid 1 (TRPV1) and 2 (TRPV2) in human peripheral blood; Molecular Immunology
Genotypically defined β-lactamase-negative ampicillin-resistant isolates of non-typable Haemophilus influenzae are associated with increased invasion of bronchial epithelial cells in vitro; Journal of Medical Microbiology
Glutathione Peroxidase and Superoxide Dismutase: Genotype and Enzyme Activity in Progression of Chronic Kidney Disease; ASM of the Australian and New Zealand Society of Nephrology
Glutathione Peroxidase and Superoxide Dismutase: Genotype and Enzyme Activity in Progression of Chronic Kidney Disease; AHMRC/ASCEPT
Glutathione peroxidase and superoxide dismutase: genotype and enzyme activity in progression of chronic kidney disease; World Congress of Nephrology
Glutathione Peroxidase Genotype and Enzyme Activity in Chronic Kidney Disease; World Congress of Nephrology
Glutathione Peroxidase Genotype and Enzyme Activity in Chronic Kidney Disease; ASM of the Australian and New Zealand Society of Nephrology
Glutathione peroxidase, superoxide dismutase and catalase genotypes and activities and the progression of chronic kidney disease; Nephrology Dialysis Transplantation
Inability of Haemophilus haemolyticus to invade respiratory epithelial cells in vitro; Journal of Medical Microbiology
Inhibition of Human Haematological Malignant Cell Lines by Capsaicin is not TRPV1-Mediated; Annual Combined ASM of the HSANZ/ANZBT/ASTH and the APSTH
Leukocyte TRPV1 Expression and Function in Health and Disease; AIMS/AACB 2011
Molecular Diagnostic Methods; 2003 RCPA AACB Chemical Pathology Course
Mononuclear cell transient receptor potential vanilloid 1 (TRPV1) expression and susceptibility to N-arachidonoyl-dopamine (NADA)-induced cell death in end-stage kidney disease (ESKD) patients; AHMRC/ASCEPT
Nittys; 2003 RCPA AACB Chemical Pathology Course
PCR screening for the N526K substitution in isolates of Haemophilus influenzae and Haemophilus haemolyticus; Journal of Antimicrobial Chemotherapy
Polyphenol administration impairs T-cell proliferation by imprinting a distinct dendritic cell maturational profile; European Journal of Immunology
Quantitative detection of G. catenatum by qPCR based on the rDNA-ITS and sxtA4 genes; The 16th International Conference on Harmful Algae
Relationship between antioxidant enzyme genotype and activity and kidney function: a case-control study; Clinical Nephrology
Relationships between single nucleotide polymorphisms of antioxidant enzymes and disease; Gene
Role of Chemokine Ligand CCL20 and its Receptor CCR6 in lntestinal Inflammation
Secretory leukoprotease inhibitor is required for efficient quercetin-mediated suppression of TNFα secretion; Oncotarget
Tachykinin (NK1) (NK2) (NK3) and transient receptor potential vanilloid 1 (TRPV1) mRNA expression in rat tissues 24 hours after capsaicin administration; Joint Meeting of ACEPT and APSA
Tachykinin (NK1, NK2 and NK3) receptor, transient receptor potential vanilloid 1 (TRPV1) and early transcription factor, cFOS, mRNA expression in rat tissues following systemic capsaicin treatment; Regulatory Peptides
Tachykinin receptor (NK1, NK2, NK3) message in the rat brain stem: effect of systemic capsaicin administration; ASCEPT 2001
Tasmanian haemochromatosis study; AIMS 2000
The murine appendiceal microbiome is altered in spontaneous colitis and its pathological progression; Gut pathogens
The prevelence of thrombophilic mutations in Tasmanian patients with venous thrombosis; 10th Asian-Pacific Congress of Clinical Biochemistry
Transient receptor potential vanilloid (TPRV) 1 and 2 Channel message and immunoreactivity in human mononuclear cells; APSA and ASCEPT
Transient receptor potential vanilloid 1 (TRPV1) and TRPV2 mRNA expression and immunoreactivity on monocytes ; AHMRC/ASCEPT
Transient receptor potential vanilloid 1 (TRPV1) channel message and immunoreactivity in peripheral blood mononuclear cells of end-stage renal disease (ESRD) patients; ASCEPT-SEAWP 2007
Transient receptor potential vanilloid 1 (TRPV1) in nave and THP-1 monocytes: role in cytokine release; ASCEPT '10
Transient receptor potential vanilloid 1 (TRPV1) IN the THP-1 monocytic cell line; ASCEPT 2009
TRPV1, NK1 receptor and substance P immunoreactivity and gene expression in the rat lumbosacral spinal cord and urinary bladder after systemic, low dose vanilloid administration; Regulatory Peptides
Undergraduate clinical biochemistry: contextualising scientific compentencies for the modern laboratory; Australasian Association of Clinical Biochemists, 50th Annual Scientific Conference

Research Projects

Are altered penicillin binding proteins in H.influenzae associated with increased capacity to invade respiratory epithelial cells?; Clifford Craig Foundation (CCFoundation)
Biomarkers of chronic kidney disease and its progression in Northern Tasmanians; Clifford Craig Foundation (CCFoundation)
Can blockade of inflammasomes be a therapeutic option in inflammatory bowel disease (IBD)?- A pilot study; Clifford Craig Foundation (CCFoundation)
Exploring the mechanisms responsible for the early transformation from chronic colitis to colorectal cancer; Cancer Council of Tasmania (CCT)
Inhibition of platelet aggregation by vanilloid-like agents: a novel antithrombotic mechanism in patients with Systemic Lupus Erythematosus?; Clifford Craig Foundation (CCFoundation)
Macrolide resistance in patients with chronic respiratory infections; Clifford Craig Foundation (CCFoundation)
Molecular Biological Studies of Tachykinin Receptor regulation by Vanilloids; University of Tasmania (UTAS)
Preliminary development of a probiotic to minimise respiratory infection with Haemophilus influenzae; Clifford Craig Foundation (CCFoundation)
Tachykinin Receptor Expression Localisation and Regulation by Vanilloid Administration; University of Tasmania (UTAS)
The landscape of gene expression changes in the aqueous humor drainage pathway of glaucoma patients; Clifford Craig Foundation (CCFoundation)
Whole genome sequencing of non-typeable H. influenzae to unravel pathogenesis and persistence; University of Tasmania (UTAS)

Research Candidate Supervision

Acquired Macrolide Resistance Genes in Non-typeable Haemophilus influenzae
Analysing the Regulatory and Effector T Cell Balance in Inflammatory Bowel Disease- Can the CCR6-CCL20 axis be exploited as a therapeutic Target
Identification of genes involved in increased invasiveness of transformed non-invasive nontypeable Haemophilus influenzae (NTHi) strain with invasive strain DNA using whole genome sequencing.
Influence of Antioxidant Genotype and Antioxidant Status on Progression of Chronic Kidney Disease
Selenium, Zinc and Copper Status in Tasmania- Dietary, Lifestyle and Some Genetic Associations