Web Access Research Portal

Researcher: Darby, JM (Ms Jocelyn Darby)

Fields of Research

Animal immunology
Cellular immunology
Medical parasitology
Innate immunity
Host-parasite interactions
Population ecology
Infectious agents

Research Objectives

Clinical health
Terrestrial biodiversity
Expanding knowledge in the biological sciences
Other health
Control of pests, diseases and exotic species in terrestrial environments

Career Best Publications

Research Publications

A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers; Science Advances
A second transmissible cancer in Tasmanian devils; Proceedings of the National Academy of Sciences
Absence of tumor necrosis factor supports alternative activation of macrophages in the liver after infection with Leishmania major; Frontiers in Immunology
Both Tumor Necrosis Factor Receptor Signaling Pathways Contribute to Mortality but not to Splenomegaly in Generalized Lymphoproliferative Disorder; Antibodies
CCR7 facilitates the pro-inflammatory function of dendritic cells in experimental leishmaniasis; Parasite Immunology
Generation and testing of Fluorescent Adaptable Simple Theranostic (FAST) Proteins; Bio-protocol
Generation and Testing of Fluorescent Adaptable Simple Theranostic (FAST) Proteins; Bio-protocol
Heat shock proteins expressed in the marsupial Tasmanian devil are potential antigenic candidates in a vaccine against devil facial tumour disease; PLoS ONE
Mitogen activated Tasmanian devil blood mononuclear cells kill devil facial tumour disease cells; Immunology and Cell Biology
NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in 3 transmissible cancers; Journal of Cancer Research and Clinical Oncology
Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils; Scientific Reports
Tasmanian devil CD28 and CTLA4 capture CD80 and CD86 from adjacent cells; Developmental and Comparative Immunology
The immunomodulatory small molecule imiquimod induces apoptosis in devil facial tumour cell lines; PL o S One
TNF may negatively regulate phagocytosis of Devil Facial Tumour Disease cells by activated macrophages; Immunological Investigations
Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii); Cellular and Molecular Life Sciences

Research Projects

Distribution, prevalence and epidemiology of DFTD and DFT2 on the d Entrecasteaux channel area; University of Tasmania Foundation Inc (UTF)

Research Candidate Supervision