Web Access Research Portal

Researcher: Tristram, SG (Dr Stephen Tristram)

Fields of Research

Medical Bacteriology
Infectious Diseases
Respiratory Diseases
Medical Biochemistry: Nucleic Acids
Pharmaceutical Sciences
Microbial Genetics
Medical Infection Agents (incl. Prions)
Animal Physiology - Systems
Structural Biology (incl. Macromolecular Modelling)
Infectious Agents
Public Health and Health Services
Bacteriology
Clinical Microbiology
Mycology
Medical Microbiology
Enzymes
Clinical Chemistry (diagnostics)
Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
Veterinary Epidemiology
Cell Development, Proliferation and Death
Cell Neurochemistry
Allergy
Veterinary Microbiology (excl. Virology)
Veterinary Pathology
Medical Parasitology
Gastroenterology and Hepatology

Research Objectives

Infectious Diseases
Diagnostic Methods
Respiratory System and Diseases (incl. Asthma)
Health
Digestive System Disorders
Expanding Knowledge in the Environmental Sciences
Education and Training Systems
Veterinary Diagnostics
Surgical Methods and Procedures
Fisheries - Aquaculture
Expanding Knowledge in the Biological Sciences
Expanding Knowledge in the Chemical Sciences
Immune System and Allergy
Nervous System and Disorders
Human Pharmaceutical Treatments (e.g. Antibiotics)
Endocrine Organs and Diseases (excl. Diabetes)
Mental Health Services
Expanding Knowledge in the Medical and Health Sciences
Inherited Diseases (incl. Gene Therapy)

Career Best Publications

Antimicrobial resistance in H. influenzae
Characterization of extended-spectrum beta-lactamase-producing isolates of Haemophilus parainfluenzae; Journal of Antimicrobial Chemotherapy
Genotypically defined β-lactamase-negative ampicillin-resistant isolates of non-typable Haemophilus influenzae are associated with increased invasion of bronchial epithelial cells in vitro; Journal of Medical Microbiology
Prevalence and genotypic characteristics of β-lactamase-negative ampicillin-resistant Haemophilus influenzae in Australia; Journal of Antimicrobial Chemotherapy
Prevalence and mechanisms of B-lactam resistance in Haemophilus haemolyticus; Journal of Antimicrobial Chemotherapy
Role of inter-species recombination of the ftsI gene in the dissemination of altered penicillin-binding-protein-3-mediated resistance in Haemophilus influenzae and Haemophilus haemolyticus; Journal of Antimicrobial Chemotherapy

Research Publications

blaROB-1 Location on pB1000 in Haemophilus influenzae is widespread and variable cefaclor resistance is associated with altered penicillin-binding proteins; Antimicrobial Agents and Chemotherapy
Haemophilus haemolyticus is infrequently misidentified as Haemophilus influenzae in diagnostic specimens in Australia; Diagnostic Microbiology and Infectious Disease
Haemophilus haemolyticus secretes a novel bacteriocin-like substance that inhibits nontypeable Haemophilus influenzae; Australian Society for Microbiology Annual Scientific Meeting 2017
A comparison of Etest, M.I.C.Evaluator strips and CLSI broth microdilution for determining B-lactam antimicrobial susceptibility in Haemophilus influenzae; Journal of Antimicrobial Chemotherapy
A Comparison of Etest, M.I.C.EvaluatorTM Strips and CLSI Microbroth Dilution for determining -lactam Antimicrobial Susceptibility in Haemophilus influenzae; Australian Society for Microbiology
A comparison of MIC-based screening tests for betalactamase-negative ampicillin-resistant Haemophilus influenzae; European Congress on Clinical Microbiology and Infectious Diseases
A multiplex PCR for β-lactamase genes of Haemophilus influenzae and description of a new blaTEM promoter variant; Journal of Antimicrobial Chemotherapy
A screening test for ESBLs in H. Influenzae; Interscience Conference on Antimicrobials and Chemotherapy
Acquired macrolide resistance genes in Haemophilus influenzae?; Journal of Antimicrobial Chemotherapy
Alternative oxidase: a possible target of anti-Candida therapy; Health & Medical Research Week Scientific Meeting
An in silico model of the alternative oxidase; International Journal of Biosciences and Technology
An evaluation of SNP-based PCR methods for the detection of -lactamase-negative ampicillin-resistant Haemophilus influenzae; Journal of Infection and Chemotherapy
An isolate of Haemophilus haemolyticus produces a bacteriocin-like substance that inhibits the growth of nontypeable Haemophilus influenzae; International Journal of Antimicrobial Agents
Antimicrobial resistance in cystic fibrosis isolates of Haemophilus influenzae; British Journal of Biomedical Science
Antimicrobial resistance in H. influenzae
Antimicrobial susceptibility testing of cystic fibrosis and non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa: a comparison of three methods; British Journal of Biomedical Science
Book review - An Atlas of Medical Microbiology by DI Slater, T. Lo and L Narayan; Australian Journal of Medical Science
Can the pathogenicity of Candida spp. be related to growth rate?; Health & Medical Research Week Scientific Meeting
Chapter 7: Haemophilus influenzae and antimicrobial susceptibility; Antimicrobial Susceptibility Testing Methods and Practices with an Australian Perspective
Characterisation of Novel -lactamase genes in Haemophilus influenzae; Australian Society for Microbiology National Scientific Meeting
Characterisation of ROB-1 producing strains of H. influenzae; Australian Society for Microbiology
Characterization of extended-spectrum beta-lactamase-producing isolates of Haemophilus parainfluenzae; Journal of Antimicrobial Chemotherapy
Combination of altered PBPs and expression of cloned extended-spectrum beta-lactamases confers cefotaxime resistance in Haemophilus influenzae; Journal of Antimicrobial Chemotherapy
Could ESBL's Emerge in -Lactamase Positive Amoxicillan/Clavulanate Resistant Strains of H. influenzae; Australian Society for Microbiology Scientific Conferrence in Canberra
Development and Evaluation of Pyocin Supplemented Chocolate Agar for the Selective Isolation of Haemophilus influenzae from Cystic Fibrosis Patients; Australian Society for Microbiology
Disc diffusion based screening tests for ESBLs in H. Influenzae; Proceedings of the Australian Society for Antimicrobials
Disc diffusion-based screening tests for extended-spectrum β-lactamases in Haemophilus influenzae; Journal of Antimicrobial Chemotherapy
Effect of Altered PBP3 on Haemophilus Influenzae expressing cloned ESBL's; Interscience Conference on Antimicrobial Agents and Chemotherapy
Effect of cloned inhibitor resistant TEM B-lactamases on the susceptibility of H. influenzae to amoxicillin/clavulanate; Journal of Antimicrobial Chemotherapy
Effect of epithelial cell type on in vitro invasion of non-typeable Haemophilus influenzae; Journal of microbiological methods
Effect of extended-spectrum -lactamases on the susceptibility of Haemophilus influenzae to cephalosporins; Journal of Antimicrobial Chemotherapy
Effect of promoter type on relative fitness of H. Influenzae and E. Coli; Australioan Society for Microbiology National Scientific Meeting
Eosinophilic enteritis caused by Enterbius vermicularis; 1998 National Scientific Meeting of the Australian Institute of Medical Scientists
Expression of acquired macrolide resistance genes in Haemophilus influenzae; Journal of Antimicrobial Chemotherapy
Extended spectrum beta-lactamases in Haemophilus?
Extended spectrum beta-lactamases: are we losing the battle?
Extended spectrum -lactamases in Haemophilus influenzae; ASM Annual Scientific Meeting
Genotypically defined β-lactamase-negative ampicillin-resistant isolates of non-typable Haemophilus influenzae are associated with increased invasion of bronchial epithelial cells in vitro; Journal of Medical Microbiology
Haemophilus haemolyticus as a potential reservoir for ftsI gene mutations and altered penicillin-binding protein 3 mediated resistance in Haemophilus influenzae; European Congress on Clinical Microbiology and Infectious Diseases
Identifying Haemophilus haemolyticus and Haemophilus influenzae by SYBR Green real-time PCR; Journal of microbiological methods
Inability of Haemophilus haemolyticus to invade respiratory epithelial cells in vitro; Journal of Medical Microbiology
Interspecies transfer of the penicillin-binding protein 3-encoding gene ftsI between Haemophilus influenzae and Haemophilus haemolyticus can confer reduced susceptibility to β-lactam antimicrobial agents; Antimicrobial Agents and Chemotherapy
Maternal and neonatal sepsis caused by Haemophilus influenzae type d; Journal of Medical Microbiology
Molecular detection of Haemophilus influenzae in COPD sputum is superior to conventional culturing methods; British Journal of Biomedical Science
Novel blaTEM-positive ampicillin-susceptible strains of Haemophilus influenzae; Journal of Infection and Chemotherapy
Novel -Lactamase Positive Ampicillin Susceptible Strains of H. influenzae; Australian Society for Microbiology
Optimization of Multiples PCR to Detect blaGenes in Haemophilius influenzae; Australian Society for Microbiology Conference
PCR screening for beta-lactamase-negative ampicillin-resistant strains of Haemophilus influenzae; European Congress on Clinical Microbiology and Infectious Diseases
PCR screening for the N526K substitution in isolates of Haemophilus influenzae and Haemophilus haemolyticus; Journal of Antimicrobial Chemotherapy
Prevalence and genotypic characteristics of β-lactamase-negative ampicillin-resistant Haemophilus influenzae in Australia; Journal of Antimicrobial Chemotherapy
Prevalence and mechanisms of B-lactam resistance in Haemophilus haemolyticus; Journal of Antimicrobial Chemotherapy
Prevalence of BLNAR strains of H. influenzae in Australia; Australian Society for Antimicrobials
Relationship between clinical site of isolation and ability to form biofilms in vitro in nontypeable Haemophilus influenzae; Canadian Journal of Microbiology
Reliability of Haemophilus influenzae biofilm measurement via static method, and determinants of in vitro biofilm production; Canadian Journal of Microbiology
Role of inter-species recombination of the ftsI gene in the dissemination of altered penicillin-binding-protein-3-mediated resistance in Haemophilus influenzae and Haemophilus haemolyticus; Journal of Antimicrobial Chemotherapy
Salicylhydroxamic Acid Inhibits the Growth of Candida albicans; International Journal of Biological and Life Sciences
Screening and Identifying BLNAR and BLPACR strains of H. influenzae; Australian Society for Antimicrobials
Sequences of small blaTEM-encoding plasmids in Haemophilus influenzae and description of variants falsely negative for blaTEM by PCR; Journal of Antimicrobial Chemotherapy
Surgical masks: operative field contamination following visor-to-visor contact; ANZ Journal of Surgery
Survival, adhesion and immunomodulatory efficacy of spore-forming probiotic Bacillus coagulans; Australian Society for Microbiology National Scientific Meeting, Hobart 2017
Susceptibility testing of H. influenzae: is a -lactamase test enough?; Australian Society for Microbiology
Susceptibility Testing of H. influenzae: is it worth bothering?; Australian Society for Microbiology National Scientific Meeting
TEM-15 ESBL and altered PBP3 in multi-resistant strains of H. parainfluenzae; Australian Society for Antimicrobials
The effect of artificially introduced inhibitor resistant TEM -lactamases (IRT's) on the susceptibility of H. influenzae to amoxycillin-clavulanate; Australian Society for Antimicrobials
The Impacts of Iron Laden Particulate Matter on NTHi Growth; Australian Society for Microbiology Annual Scientific Meeting 2017
Variation in selected regions of blaTEM genes and promoters in Haemophilus influenzae; Journal of Antimicrobial Chemotherapy
-Lactam Resistance in Haemophilus influenzae; Australian Society for Microbiology

Research Projects

An Amoeba Co-culture Assay Alternative to Mammalian Models of Bacterial Virulence Testing; The MAWA Trust (MAWA)
Are altered penicillin binding proteins in H.influenzae associated with increased capacity to invade respiratory epithelial cells?; Clifford Craig Foundation (CCFoundation)
Characterisation of Extended Spectrum B-Lactamases and Cephalosporin Resistance in Clinical Isolates of H. parainfluenzae; Clifford Craig Foundation (CCFoundation)
Development and Evaluation of Laboratory Tests to Detect Important Emerging Antibiotic Resistance in Haemophilus Influenzae; Clifford Craig Foundation (CCFoundation)
Development and Evaluation of New Selective Culture Medium for Isolation of Haemophilus Influenzae from Cystic Fibrosis Patients; Clifford Craig Foundation (CCFoundation)
Effect of Variant Gene Expression on Antibiotic Resistance in Haemophilus Influenzae and the Implications for Dissemination of Resistance Genes; Clifford Craig Foundation (CCFoundation)
Extended Spectrum B-Lactamase in Haemophilus; Clifford Craig Foundation (CCFoundation)
Genetic Variation in B-Lactamase Genes in Haemophilus Influenzae; Clifford Craig Foundation (CCFoundation)
Influence of Specific Prescribing Practices on the Rapid Emergence of Antibiotic Resistance in Haemophilus Influenzae; Clifford Craig Foundation (CCFoundation)
Investigation of Antibiotic Sensitivity & Virulence Factors of the Tasmanian Clonal Strain of Pseudomonas aeuruginosa Isolated from Cystic Fibrosis Patients; Clifford Craig Foundation (CCFoundation)
Is Haemophilus haemolyticus a pathogen?; Royal Hobart Hospital Research Foundation (RHHRF)
Macrolide resistance in patients with chronic respiratory infections; Clifford Craig Foundation (CCFoundation)
Platypus Partnership - A Community and Science-based Conservation Programme; Natural Heritage Trust (NHT)
Preliminary development of a probiotic to minimise respiratory infection with Haemophilius influenzae; Clifford Craig Foundation (CCFoundation)
Resistance to Macrolide and Fluoroquinolone Antibiotics in Haemophilus Influenzae; Clifford Craig Foundation (CCFoundation)
Testing a new therapy against lung infections for people with cystic fibrosis; Clifford Craig Foundation (CCFoundation)
The Acquisition of New Strains of Non-Typeable Haemophilus Influenzae Is The Leading Cause of Acute Exacerbations in Tasmanian COPD Patients; Clifford Craig Foundation (CCFoundation)
Whole genome sequencing of non-typeable H. influenzae to unravel pathogenesis and persistence; University of Tasmania (UTAS)

Research Candidate Supervision

Acquired Macrolide Resistance Genes in Non-typeable Haemophilus influenzae
Application of Raman Spectroscopy to the Evaluation of Biofilm Formation and Virulence of Pathogenic Microorganisms
Identification of genes involved in increased invasiveness of transformed non-invasive nontypeable Haemophilus influenzae (NTHi) strain with invasive strain DNA using whole genome sequencing.
Microbial Interference with the Pathagenicity of Nontypeable Haemophilus Influenzae
Phenotypic and genotypic characterisation of altered penicillin-binding protein 3 (PBP3) mediated resistance in Haemophilus influenzae and Haemophilus haemolyticus