Web Access Research Portal

Researcher: Malley, RC (Dr Roslyn Malley)

Fields of Research

Cellular immunology
Tumour immunology
Cancer genetics
Medical bacteriology
Medicine, nursing and health curriculum and pedagogy
Preventative health care
Cancer cell biology
Animal immunology
Molecular targets
Medical virology
Innate immunity
Solid tumours
Oncology and carcinogenesis

Research Objectives

Clinical health
Diagnosis of human diseases and conditions
Other health
Assessment, development and evaluation of curriculum
Preventive medicine
Terrestrial biodiversity
Treatment of human diseases and conditions

Career Best Publications

Research Publications

Pandoraea fibrosis sp. nov., a novel Pandoraea species isolated from clinical respiratory samples; International Journal of Systematic and Evolutionary Microbiology
Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis; Frontiers in microbiology
A rare variant in EZH2 is associated with prostate cancer risk; International Journal of Cancer
Alterations of Langerhans cell function during the early stages of cutaneous carcinogenesis confers immunosuppression rather than immunity; International Investigative Dermatology
Cadaver path: Integration of anatomy and anatomical pathology in the dissection laboratory; Australian & New Zealand Association of Clinical Anatomists
Carcinogen-modified dendritic cells induce immunosuppression by incomplete T-cell activation resulting from impaired antigen uptake and reduced CD86 expression; Immunology
Dietary vitamin D alters the response of the skin to UVB-irradiation depending on the genetic background of the mice; Photochemical & Photobiological Sciences
Dietary Vitamin D3 deficiency alters skin UVB-induced DNA damage in neonatal mice; The Third Australian Health and Medical Research Congress
Dietary vitamin D3 influences UVB induced DNA damage and immunosuppression; Mutagenesis and Experimental Pathology of Australasia Conference
Dietary vitamin D3 protects against UVB-induced immunosuppression in C57BL/6, but not BALB/c mice; MEPSA Conference
Effect of UV Radiation on the Neonatal Skin Immune System - Implicaions for Melanoma; Photochemistry and Photobiology
Effect of UV Radiation on the Neonatal Skin Immune System- Implications for Melanoma
Epigenetic regulation of the ITGB4 gene in prostate cancer; Experimental Cell Research
HIT- Are we doing it right ? An audit of Heparin-induced thrombocytopenia testing at Royal Hobart Hospital; Annaul Scientific meeting HAA 2014
Immune protection against photocarcinogenesis
Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours; Scientific Reports
Langerhans cell function during the early stages of carcinogenesis; 5th International Workshop on Langerhans cells
Massively parallel sequencing in hereditary prostate cancer families reveals a rare risk variant in the DNA repair gene, RAD51C; European Journal of Cancer
Minimal effects of reduced teaching hours on undergraduate medical student learning outcomes and course evaluations; Medical Teacher
Modification of skin immune system function by dietary vitamin D3 is influenced by age and gender; The Third Australian Health and Medical Research Congress
Neonatal exposure to UVR alters skin immune system development, and suppresses immunity in adulthood; Immunology and Cell Biology
Proteomics identifies enhanced expression of stefin A in neonatal murine skin compared with adults: functional implications; British Journal of Dermatology
Reduced dendritic cell function during the early stages of chemical carcinogenesis; 27th Annual Meeting of the Australasian Society for Immunology
Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils; Scientific Reports
The skin immune system and the challenge of tumour immunosurveillance
Vitamin D deficiency alters the contact sensitivity response in BALB/c mice; 35th Annual Scientific Meeting of the Australasian Society for Immunology
Vitamin D promotes neonatal tolerance induction to contact sensitisers; Australasian Society for Immunology Meeting
Vitamin D3 deficiency enhances contact hypersensitivity in male but not in female mice ; Cellular Immunology
Vitamin D3 influences skin draining lymph node dendritic cells in neonatal male mice; National Health and Medical Research Congress
Vitamin D3 nutrition influences regulatory T cell induction in neonatal tolerance and adult immunity; MEPSA Conference
Vitamin D3, the skin immune system and cutaneous carcinogenesis; UV Workshop, National Institute of Water and Atmospheric Research (NIWA)
What's new in photoimmunology
What's new in photoimmunology?
What's new in photoimmunology?

Research Projects

A Clinical and Biospecimens Prostate Cancer Resource for Biomarker Research in Tasmania; Royal Hobart Hospital Research Foundation (RHHRF)
Investigation of chromosomal loss and gain at 7p21 in a Tasmanian hereditary prostate cancer family; Royal Hobart Hospital Research Foundation (RHHRF)
Is EEF2 a potential biomarker for more aggressive prostate cancer in Tasmanian patients?; Royal Hobart Hospital Research Foundation (RHHRF)
Non-conventional antimicrobial testing of emerging pathogens; Royal Hobart Hospital Research Foundation (RHHRF)
Prevalence and virulence of an emerging bacterial pathogen of Tasmanian cystic fibrosis patients; Royal Hobart Hospital Research Foundation (RHHRF)
Sex differences in Regulatory T cell Development and Function in NeonatalTolerance; University of Tasmania (UTAS)
The Skin Immune System in Cutaneous Carcinogenesis; National Health & Medical Research Council (NHMRC)
Vitamin D Deficiency in Skin Cancer Development; Royal Hobart Hospital Research Foundation (RHHRF)

Research Candidate Supervision