Web Access Research Portal

Researcher: Sharman, MJ (Dr Matt Sharman)

Fields of Research

Exercise physiology
Nutrition and dietetics
Neurosciences
Neurology and neuromuscular diseases
Cell metabolism
Biomechanics
Central nervous system
Receptors and membrane biology
Health promotion
Public health nutrition
Respiratory diseases
Geriatrics and gerontology
Nephrology and urology
Behavioural epidemiology
Medical biochemistry and metabolomics
Traditional, complementary and integrative medicine

Research Objectives

Evaluation of health and support services
Clinical health
Nutrition
Other health
Mental health
Behaviour and health
Public health (excl. specific population health)
Determinants of health
Rural and remote area health
Expanding knowledge in the health sciences
Preventive medicine

Career Best Publications

A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men; Journal of Nutrition
APOE genotype results in differential effects on the peripheral clearance of amyloid-beta42 in APOE knock-in and knock-out mice; Journal of Alzheimer's Disease
Cholesterol Metabolism and Transport in the Pathogenesis of Alzheimer's disease; Journal of Neurochemistry
Development of a non-targeted metabolomics method to investigate urine in a rat model of polycystic kidney disease; Nephrology
Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice; Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease; Advanced Drug Delivery Reviews
Replacing dietary carbohydrate with protein and fat decreases the concentrations of small LDL and the inflammatory response induced by atherogenic diets in the guinea pig; Journal of Nutritional Biochemistry
The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes; PLoS One
Two weeks of reduced-volume sprint interval or traditional exercise training does not improve metabolic functioning in sedentary obese men; Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics
Very low-carbohydrate and low-fat diets affect fasting lipids and postprandial lipemia differently in overweight men; Journal of Nutrition
Weight loss leads to reductions in inflammatory biomarkers after a very-low-carbohydrate diet and a low-fat diet in overweight men; Clinical Science

Research Publications

A cetylated fatty acid topical cream with menthol reduces pain and improves functional performance in individuals with arthritis; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
A comparison of diet quality in a sample of rural and urban Australian adults; Nutrients
A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men; Journal of Nutrition
A randomized controlled trial of adherence to a 24-month home-based physical activity program and the health benefits for older adults at risk of Alzheimer’s disease: The AIBL active-study; Journal of Alzheimer's Disease
A Very Low-Carbohydrate Diet Results in Greater Reductions in Body Weight, Whole Body Fat, and Trunk Fat Than a Low-Fat Diet in Overweight Subjects; Federation of American Societies for Experimental Biology Conference
Achieving physical activity guideline recommendation in older adults at risk of cognitive deterioration
Alterations in dorsal and ventral posterior cingulate connectivity in APOE ε4 carriers at risk of Alzheimer's disease; British Journal of Psychiatry Open
An isoenergetic very low carbohydrate diet improves serum HDL cholesterol and triacylglycerol concentrations, the total cholesterol to HDL cholesterol ratio and postprandial lipemic responses compared with a low fat diet in normal weight, normolipidemic women; Journal of Nutrition
Androgen receptor content following heavy resistance exercise in men; Journal of Steroid Biochemistry and Molecular Biology
Androgenic responses to resistance exercise: effects of feeding and L-carnitine; Medicine and Science in Sports and Exercise
APOE genotype results in differential effects on the peripheral clearance of amyloid-beta42 in APOE knock-in and knock-out mice; Journal of Alzheimer's Disease
Assessment of diets containing curcumin, epigallocatechin-3-gallate, docosahexaenoic acid and α-lipoic acid on amyloid load and inflammation in a male transgenic mouse model of Alzheimer's disease: Are combinations more effective?; Neurobiology of Disease
Association between cardiovascular risk and cognitive measures among older adults at risk of cognitive decline
Association between cognitive function and clustered cardiovascular risk of metabolic syndrome in older adults at risk of cognitive decline; Journal of Nutrition, Health and Aging
Barriers to and enablers of achieving a healthy diet in Tasmanian adults: The Tasmania Project Report 62
Baseline white matter is associated with physical fitness change in preclinical Alzheimer's disease; Frontiers in Aging Neuroscience
Body composition and hormonal responses to a carbohydrate-restricted diet; Metabolism: Clinical and Experimental
Can older adults at risk of Alzheimer's disease adhere to a 24-month home-based physical activity program? The AIBL Active-Trial
Carbohydrate restriction alters hepatic cholesterol metabolism in guinea pigs fed a hypercholesterolemic diet; Journal of Nutrition
Cardiovascular and hormonal aspects of very-low-carbohydrate ketogenic diets; Obesity Research
Changes in myosin heavy chain composition with heavy resistance training in 60- to 75-year-old men and women; European Journal of Applied Physiology
Cholesterol Metabolism and Transport in the Pathogenesis of Alzheimer's disease; Journal of Neurochemistry
Comparison of a very low-carbohydrate and low-fat diet on fasting lipids, LDL subclasses, insulin resistance, and postprandial lipemic responses in overweight women; American College of Nutrition Journal
Comparison of energy-restricted very low-carbohydrate and low-fat diets on weight loss and body composition in overweight men and women; Nutrition & Metabolism
Comparison of liquid versus ice slurry solutions on core temperature during simulated mining conditions; Future of Fatigue in Exercise Symposium
Comparison of short-term sprint interval vs. traditional exercise training on metabolic adaptations in sedentary overweight/obese men; 16th Annual Congress of the European College of Sport Sciences
Cortitrol supplementation reduces serum cortisol responses to physical stress; Metabolism: Clinical and Experimental
Detraining produces minimal changes in physical performance and hormonal variables in recreationally strength-trained men; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
Development of a non-targeted metabolomics method to investigate urine in a rat model of polycystic kidney disease; Nephrology
Dietary carbohydrate and cholesterol influence the number of particles and distributions of lipoprotein subfractions in guinea pigs; Journal of Nutritional Biochemistry
Effect of a 24-month physical activity program on brain changes in older adults at risk of Alzheimer's disease: the AIBL active trial; Neurobiology of Aging
Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis; Journal of Rheumatology
Effect of explosive resistance training on titin and myosin heavy chain isoforms in trained subjects; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
Effect of nutritional supplement therapies in the prevention of Alzheimer's disease in a transgenic mouse model; The joint ASM of The Nutrition Society of Australia and the Nutrition Society of New Zealand
Effects of a carbohydrate-restricted diet with and without supplemental soluble fiber on plasma low-density lipoprotein cholesterol and other clinical markers of cardiovascular risk; Metabolism: Clinical and Experimental
Effects of a high-fat diet on postabsorptive and postprandial testosterone responses to a fat-rich meal; Metabolism: Clinical and Experimental
Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice; Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology
Effects of a physical activity intervention on brain atrophy in older adults at risk of dementia: a randomized controlled trial; Brain Imaging and Behavior
Effects of Chromium Supplementation on Glycogen Synthesis after High-Intensity Exercise; Medicine and Science in Sports and Exercise
Effects of treatment with a cetylated fatty acid topical cream on static postural stability and plantar pressure distribution in patients with knee osteoarthritis; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
Effects of vitamin E supplementation on recovery from repeated bouts of resistance exercise; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
Endurance capacity and high-intensity exercise performance responses to a high fat diet; International Journal of Sport Nutrition and Exercise Metabolism
Fasting and postprandial lipid responses to a hypoenergetic ketogenic and low-fat diet in men; American College of Sports Medicine Conference
High intake of cholesterol results in less atherogenic low-density lipoprotein particles in men and women independent of response classification; Metabolism: Clinical and Experimental
High-affinity growth hormone binding protein and acute heavy resistance exercise; Medicine and Science in Sports and Exercise
Hormonal responses to a 160km race (Susitna 100) across frozen Alaska; American College of Sports Medicine Conference
Hormonal Responses to Energy-Restricted Very Low-Carbohydrate and Low-Fat Diets Are Related to Changes in Whole Body andTrunk Fat Mass; Federation of American Societies for Experimental Biology Conference
Incentivising public transport use for physical activity gain: process evaluation of the COVID-19 disrupted trips4health randomised controlled trial; The International Journal of Behavioral Nutrition and Physical Activity
Increasing fluid milk favourably affects bone mineral density responses to resistance training in adolescent boys; American Dietetic Association. Journal
Inflammation in Alzheimer’s Disease, and Prevention with Antioxidants and Phenolic Compounds – What Are the Most Promising Candidates?; Neurodegeneration and Alzheimer's Disease: The Role of Diabetes, Genetics, Hormones, and Lifestyle
Influence of Catecholamines on Muscle Force Production; American College of Sports Medicine Conference
Influence of muscle strength and total work on exercise-induced plasma growth hormone isoforms in women; Journal of Science and Medicine in Sport
Is greater public transport use associated with higher levels of physical activity in a regional setting? Findings from a pilot study; Pilot and Feasibility Studies
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease; Advanced Drug Delivery Reviews
Longitudinal tracking of muscular power changes of NCAA Division I collegiate women gymnasts; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
Maintenance of the LDL cholesterol:HDL cholesterol ratio in an elderly population given a dietary cholesterol challenge; Journal of Nutrition
Modification of lipoproteins by very low-carbohydrate diets; Journal of Nutrition
Muscle fiber characteristics in patients with peripheral arterial disease; Medicine and Science in Sports and Exercise
Novel promising therapeutics against chronic neuroinflammation and neurodegeneration in Alzheimer's disease; Neurochemistry International
Physiological and functional effects of acute low-frequency hand-arm vibration; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
Profiling brain and plasma lipids in human APOE epsilon2, epsilon3, and epsilon4 knock-in mice using electrospray ionization mass spectrometry; Journal of Alzheimer'S Disease
Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: The AIBL Active trial; BMC Psychiatry
Relationship between postprandial lipemia and LDL particle size during a ketogenic diet in men; American College of Sports Medicine Conference
Relationship of established cardiovascular risk factors and peripheral biomarkers on cognitive function in adults at risk of cognitive deterioration; Journal of Alzheimer's Disease
Replacing dietary carbohydrate with protein and fat decreases the concentrations of small LDL and the inflammatory response induced by atherogenic diets in the guinea pig; Journal of Nutritional Biochemistry
Resistance training in patients with peripheral arterial disease: effects on myosin isoforms, fiber type distribution, and capillary supply to skeletal muscle; Journals of Gerontology. Series A: Biological Sciences and Medical Sciences
Responses of plasma proenkephalin peptide F in rats following 14 days of spaceflight; Aviation, Space, and Environmental Medicine
Safety measures of L-carnitine L-tartrate supplementation in healthy men; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
Semi-automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration; Journal of Magnetic Resonance Imaging
Statistical analysis of fiber area in human skeletal muscle; Canadian Journal of Applied Physiology
Targeting inflammatory pathways in Alzheimer's disease: a focus on natural products and phytomedicines; CNS Drugs
The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice; Neuroscience: An International Journal
The effects of amino acid supplementation on muscular performance during resistance training overreaching; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
The effects of carbohydrate loading on repetitive jump squat power performance; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching; European Journal of Applied Physiology
The effects of L-carnitine L-tartrate supplementation on hormonal responses to resistance exercise and recovery; Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association
The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes; PLoS One
The short- and long- term effects of a 24-month home-based physical activity program on physical activity levels and body composition of older adults at risk of Alzheimer's disease: the AIBL Active Trial
Two weeks of reduced-volume sprint interval or traditional exercise training does not improve metabolic functioning in sedentary obese men; Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics
Very low-carbohydrate and low-fat diets affect fasting lipids and postprandial lipemia differently in overweight men; Journal of Nutrition
Weight loss associated with reduced intake of carbohydrate reduces the atherogenicity of LDL in premenopausal women; Metabolism: Clinical and Experimental
Weight loss leads to reductions in inflammatory biomarkers after a very-low-carbohydrate diet and a low-fat diet in overweight men; Clinical Science

Research Projects

A RANDOMISED CLINICAL TRIAL OF PHYSICAL ACTIVITY TO DELAY THE PROGRESSION OF CEREBROVASCULAR PATHOLOGY; National Health & Medical Research Council (NHMRC)
Co-design of an educational intervention to improve bowel cancer awareness and screening in a rural community; Cancer Council of Tasmania (CCT)
Determining dose response variations in human absorption and metabolism of anthocyanins from Tasmanian sweet cherries: a pilot cross-over study; University of Tasmania (UTAS)
The role of a presenilin 2 truncation (PS2V) in Alzheimer's Disease; National Health & Medical Research Council (NHMRC)

Research Candidate Supervision