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Individual Researchers Report

Researcher Bio

Researcher:Dr M Ambrose
School/Unit:Medicine
Commenced with Institution:30/3/2012
Commenced Current Job:30/3/2012
UTAS Profile:Visit my UTAS Profile page

Citations sourced from WOS® and Scopus

Top 3 Fields of Research
Medical Bacteriology
Anthropological Genetics
Pharmaceutical Sciences
Top 3 Research Objectives
Endocrine Organs and Diseases (excl. Diabetes)
Infectious Diseases
Respiratory System and Diseases (incl. Asthma)

Research Funding

AdministeredResearch TeamInitial YearDuration (Years)Funding Body/ClientTitle of ProjectTotal Cash $Total In-Kind $
University of TasmaniaDr M Ambrose; Dr S Beggs20181Royal Hobart Hospital Research Foundation: Grant-Starter; Royal Hobart HospitalCystic Fibrosis: Investigating the acute stage of infection by Pseudomonas aeruginosa10,000
University of TasmaniaDr LF Roddam; Dr S Beggs; Dr M Ambrose; Dr RC Malley20171Royal Hobart Hospital Research Foundation: Grant-Starter; Royal Hobart HospitalNon-conventional antimicrobial testing of emerging pathogens10,000
University of TasmaniaDr KH Brettingham-Moore; Dr M Ambrose; AssocProf AF Holloway; Dr M Skala; Dr PC Taberlay20161Cancer Council of Tasmania: Grant-Cancer ResearchMolecular profiling of the post radiotherapy chromatin landscape in prostate cancer cells33,000
University of TasmaniaDr N Guven; AssocProf RD Eri; Dr KDK Ahuja; Professor MJ Ball; Dr M Ambrose; Dr LF Roddam; AssocProf GR Zosky20161Department of Industry, Innovation and Science; Marinova Pty Ltd: Contract ResearchAnti-inflammatory efficacy of Marinovas Fucoidan & interactions with microbiota100,000
University of TasmaniaDr LF Roddam; Dr M Ambrose; Dr S Beggs; AssocProf MA Cooley; Dr RC Malley; Dr Sanchia Warren; Dr RR Wilson; Ms B McEwan20151Royal Hobart Hospital Research Foundation: Grant-Clinical ResearchPrevalence and virulence of an emerging bacterial pathogen of Tasmanian cystic fibrosis patients11,100
University of TasmaniaDr LF Roddam; AssocProf MA Cooley; Dr M Ambrose20143Australian Cystic Fibrosis Research Trust: Scholarship-Top-UpA human paraoxonase 2-based therapy for cystic fibrosis A15,000
University of TasmaniaDr LF Roddam; AssocProf MA Cooley; Dr M Ambrose; Dr SG Tristram20131Clifford Craig Foundation: GrantTesting a new therapy against lung infections for people with cystic fibrosis67,782

Graduate Research Supervision (Current)

CommencedDegreeSupervisionTitle
1/7/2014PhDCo-supervisorThe microbial ecology of transmission sites of Tasmanian devil facial tumour disease
14/3/2018PhDCo-supervisorPotential of Recombinant Human PON2 as an Anti-Pseudomonal Therapy

Graduate Research Supervision (Graduands)

NameDegreeCompletedSupervisionCommencedCeasedTitle
Naseem Mohammad AliPhD2/11/2015Co-supervisor17/3/2014Potential of Human PON2 as an Anti-Pseudomonal Therapy
Hsien Hooi LeePhD15/10/2018Co-supervisor1/4/2016The Mutagenic Activity of Oxazolopyridine Compounds
Joanne Carmen PagnonPhD2/7/2018Co-supervisor4/11/201310/2/2015The Potential Therapeutic Benefits of rhPON2 Against Pseudomonas Aeruginosa Infections
Joanne Carmen PagnonPhD2/7/2018Co-supervisor11/2/2015The Potential Therapeutic Benefits of rhPON2 Against Pseudomonas Aeruginosa Infections

Career Best Publications

None Identified

Research Publications

Journal Article
Corban, M and Ambrose, M and Pagnon, J and Stringer, D* and Karpiniec, S* and Park, A* and Eri, R and Fitton, JH and Gueven, N, “Pathway Analysis of Fucoidan Activity Using a Yeast Gene Deletion Library Screen”, Marine drugs, 17 (1) pp. 1-15. doi:10.3390/md17010054 ISSN 1660-3397 (2019) [Refereed Article] [Full Text] [Detail]
Ambrose, M and Murray, L and Handoyo, NE* and Tunggal, D* and Cooling, N, “Learning global health: a pilot study of an online collaborative intercultural peer group activity involving medical students in Australia and Indonesia”, BMC Medical Education, 17 Article 10. doi:10.1186/s12909-016-0851-6 ISSN 1472-6920 (2017) [Refereed Article] [Full Text] [Detail]
Ambrose, M and Malley, RC and Warren, SJ* and Beggs, SA and Swallow, OFE and McEwan, B* and Stock, D* and Roddam, LF, “Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis”, Frontiers in microbiology, 7 Article 692. doi:10.3389/fmicb.2016.00692 ISSN 1664-302X (2016) [Refereed Article] [Full Text] [Detail]
Ee, R* and Ambrose, M and Lazenby, C* and Williams, P* and Chan, K-G* and Roddam, L, “Genome sequences of two Pandoraea pnomenusa isolates recovered 11 months apart from a cystic fibrosis patient”, Genome Announcements, 3 (1) Article e01389-14. doi:10.1128/genomeA.01389-14 ISSN 2169-8287 (2015) [Refereed Article] [Full Text] [Detail]
Gizdavic-Nikolaidis, MR* and Pagnon, JC and Ali, N and Sum, R and Davies, N and Roddam, LF and Ambrose, M, “Functionalized polyanilines disrupt Pseudomonas aeruginosa and Staphylococcus aureus biofilms”, Colloids and Surfaces B: Biointerfaces, 136 pp. 666-673. doi:10.1016/j.colsurfb.2015.10.015 ISSN 0927-7765 (2015) [Refereed Article] [Full Text] [Detail]
Ambrose, M and Gatti, RA*, “Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions”, Blood, 121 (20) pp. 4036-4045. doi:10.1182/blood-2012-09-456897 ISSN 0006-4971 (2013) [Refereed Article] [Full Text] [Detail]
Gizdavic-Nikolaidis, MR* and Bennett, JR* and Swift, S* and Easteal, AJ* and Ambrose, M, “Broad spectrum antimicrobial activity of functionalized polyanilines”, Acta Biomaterialia, 7 (12) pp. 4204-4209. doi:10.1016/j.actbio.2011.07.018 ISSN 1742-7061 (2011) [Refereed Article] [Full Text] [Detail]
MacPhee, DG* and Ambrose, M, “Catabolite repression of SOS-dependent and SOS-independent spontaneous mutagenesis in stationary-phase Escherichia coli”, Mutation Research, 686 (1-2) pp. 84-89. doi:10.1016/j.mrfmmm.2010.01.022 ISSN 0027-5107 (2010) [Refereed Article] [Full Text] [Detail]
Ambrose, M and Goldstine, JV* and Gatti, RA*, “Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells”, Human Molecular Genetics, 16 (18) pp. 2154-64. doi:10.1093/hmg/ddm166 ISSN 0964-6906 (2007) [Refereed Article] [Full Text] [Detail]
Rusyn, I* and Fry, RC* and Begley, TJ* and Klapacz, J* and Svensson, JP* and Ambrose, M and Samson, LD*, “Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates”, PLoS One, 2 (11) pp. e1252. doi:10.1371/journal.pone.0001252 ISSN 1932-6203 (2007) [Refereed Article] [Full Text] [Detail]
Hofseth, LJ* and Khan, MA* and Ambrose, M and Nikolayeva, O* and Xu-Welliver, M* and Kartalou, M* and Hussain, SP* and Roth, RB* and Zhou, X* and Mechanic, LE* and Zurer, I* and Rotter, V* and Samson, LD* and Harris, CC*, “The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation”, Journal of Clinical Investigation, 112 (12) pp. 1887-94. doi:10.1172/JCI200319757 ISSN 0021-9738 (2003) [Refereed Article] [Full Text] [Detail]
Ambrose, M and MacPhee, DG*, “Glucose and related catabolite repressors are powerful inhibitors of pKM101-enhanced UV mutagenesis in Escherichia coli”, Mutation Research, 422 (1) pp. 107-12. doi:10.1016/S0027-5107(98)00179-1 ISSN 0027-5107 (1998) [Refereed Article] [Full Text] [Detail]
Ambrose, M and MacPhee, DG*, “Catabolite repressors are potent antimutagens in Escherichia coli plate incorporation assays: experiments with glucose, glucose-6-phosphate and methyl-alpha-D-glucopyranoside”, Mutation Research, 398 (1-2) pp. 175-82. doi:10.1016/S0027-5107(97)00315-1 ISSN 0027-5107 (1998) [Refereed Article] [Full Text] [Detail]
MacPhee, DG* and Ambrose, M, “Spontaneous mutations in bacteria: chance or necessity?”, Genetica, 97 (1) pp. 87-101. doi:10.1007/BF00132585 ISSN 0016-6707 (1996) [Refereed Article] [Full Text] [Detail]
Conference Publication
Cooling, NB and Ambrose, M and Murray, LJ and Handoyo, NE* and Dedi, MAE*, “Reciprocal intercultural peer e-learning in global health: Experiences and perceptions of Australian and Indonesian third-year medical students”, 7th International Conference on Public health among the Greater Mekong Sub-Regional Countries, 25-27 September 2017, Hue, Vietnam (2015) [Plenary Presentation] [Detail]

* This author is not affiliated with the University of Tasmania.