Web Access Research Portal

Researcher: Zhou, Y (Mr Yuan Zhou)

Fields of Research

Central nervous system
Medical genetics (excl. cancer genetics)
Neurology and neuromuscular diseases
Rheumatology and arthritis
Biological adaptation
Environmental epidemiology
Gastroenterology and hepatology
Translational and applied bioinformatics
Health and community services
Gene mapping
Cellular nervous system
Regenerative medicine (incl. stem cells)
Health economics

Research Objectives

Clinical health
Expanding knowledge in the biomedical and clinical sciences
Expanding knowledge in the health sciences
Prevention of human diseases and conditions
Diagnosis of human diseases and conditions
Public health (excl. specific population health)
Determinants of health
Evaluation of health outcomes
Expanding knowledge in the biological sciences
Health education and promotion
Health policy evaluation

Career Best Publications

Research Publications

PRM1 variant rs35576928 (Arg>Ser) is associated with defective spermatogenesis in the Chinese Han population; Reproductive Biomedicine Online
An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3; Arthritis Research & Therapy
Assessing the consistency and validity of self-reported year of diagnosis among participants in a longitudinal study of people with multiple sclerosis; Multiple Sclerosis and Related Disorders
Association analysis of ERBB2 amplicon genetic polymorphisms and STARD3 expression with risk of gastric cancer in the Chinese population; Gene
Association analysis of genetic variants in microRNA networks and gastric cancer risk in a Chinese Han population; Journal of Cancer Research and Clinical Oncology
Association of the variant rs2243421 of human DOC-2/DAB2 interactive protein gene (hDAB2IP) with gastric cancer in the Chinese Han population; Gene
Common genetic variation within miR-146a predicts disease onset and relapse in multiple sclerosis; Neurological Sciences
Developing a clinical-environmental-genotypic prognostic index for relapsing-onset multiple sclerosis and clinically isolated syndrome; Brain Communications
Do combined assays of serum AFP, AFP-L3, DCP, GP73, and DKK-1 efficiently improve the clinical values of biomarkers in decision-making for hepatocellular carcinoma? A meta-analysis; Expert Review of Gastroenterology & Hepatology
E-Selectin rs5361 and FCGR2A rs1801274 variants were associated with increased risk of gastric cancer in a Chinese population; Molecular Carcinogenesis
Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis; Scientific Reports
Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility; Genome Medicine
EZH2 genetic variants affect risk of gastric cancer in the Chinese Han population; Molecular Carcinogenesis
Genetic analysis of ADIPOQ variants and gastric cancer risk: a hospital-based case–control study in China; Medical Oncology
Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis; Multiple Sclerosis Journal
Genetic variants in TEX15 gene conferred susceptibility to spermatogenic failure in the Chinese Han population; Reproductive Sciences
Genetic variation in PBMC-produced IFN-γ and TNF-α associations with relapse in multiple sclerosis; Journal of The Neurological Sciences
Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis; Journal of Neurology, Neurosurgery and Psychiatry
Genetic variation in WNT9B increases relapse hazard in Multiple Sclerosis; Annals of Neurology
Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis; Annals of Neurology
Genotype and phenotype in Multiple Sclerosis - potential for disease course prediction?; Current Treatment Options in Neurology
Integrating Genetic structural variations and whole genome sequencing into clinical neurology; Neurology: Genetics
Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases; Nature Communications
Lipid-related genetic polymorphisms significantly modulate the association between lipids and disability progression in multiple sclerosis; Journal of Neurology, Neurosurgery and Psychiatry
Lower limb muscle strength is associated with poor balance in middle-aged women: linear and nonlinear analyses; Osteoporosis International
Multiple Quantitative Trait Loci for Anti-EBNA-1 IgG Titres are Associated with Risk of Multiple Sclerosis
Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies; Neurology: Genetics
Novel plasma and brain proteins that are implicated in multiple sclerosis; Brain
Redefining the Multiple Sclerosis Severity Score (MSSS): the effect of sex and onset phenotype; Multiple Sclerosis Journal
Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study; Journal of Neurology, Neurosurgery and Psychiatry
The potential role of epigenetic modifications in the heritability of multiple sclerosis; Multiple Sclerosis Journal
Utilising multi-large omics data to elucidate biological mechanisms within multiple sclerosis genetic susceptibility loci; Multiple Sclerosis Journal
Variation within MBP gene predicts disease course in multiple sclerosis; Brain and Behavior

Research Projects

68th Lindau Nobel Laureates Meeting; Australian Academy of Science (AASc)
Elucidating The Genetic Architecture Of Multiple Sclerosis To Influence Improvements In Disease Outcomes; National Health & Medical Research Council (NHMRC)
Ian Ballard Travel Award Role of sex chromosomes in genetics of MS; Multiple Sclerosis Australia (MSA)
Identifying novel genetic loci associated with an increased relapse rate and disability progression in multiple sclerosis; Royal Hobart Hospital Research Foundation (RHHRF)
The modulation of multiple sclerosis (MS) relapse risk by genetic variations in the LRP2 gene; Royal Hobart Hospital Research Foundation (RHHRF)
Understanding the genetic architecture of multiple sclerosis onset and progression.; Multiple Sclerosis Australia (MSA)
Using genomic signatures of natural selection to elucidate the genetic architecture of multiple sclerosis; Multiple Sclerosis Australia (MSA)

Research Candidate Supervision