Web Access Research Portal

Researcher: Phipps, AJ (Dr Andrew Phipps)

Fields of Research

Neurology and neuromuscular diseases
Cellular nervous system
Neurosciences
Genomics
Neurogenetics
Animal physiology - cell

Research Objectives

Clinical health
Expanding knowledge in the biomedical and clinical sciences
Expanding knowledge in the biological sciences

Career Best Publications

Research Publications

Age, but not amyloidosis, induced changes in global levels of histone modifications in susceptible and disease-resistant neurons in Alzheimer's disease model mice; Frontiers in Aging Neuroscience
Alterations in neurofilaments and the transformation of the cytoskeleton in axons may provide insight into the aberrant neuronal changes of Alzheimer's disease; Brain Research Bulletin
Approach for in vivo delivery of CRISPR/Cas system: a recent update and future prospect; Cellular and Molecular Life Sciences
id #12216 - Dysregulation of the neuronal epigenome occurs prior to pathology-onset and alters with progressive amyloidosis; Australasian Neuroscience Society (ANS) 2019 Conference
Neurofilament-labeled pyramidal neurons and astrocytes are deficient in DNA methylation marks in Alzheimer's disease; Neurobiology of Aging
Neurofilament-labelled pyramidal neurons and astrocytes are deficient in DNA methylation marks in Alzheimer's disease; Epigenetics 2015 - Australian Scientific Conference
No difference in DNA methylation and hydroxymethylation marks in cortical pyramidal neurons, interneurons and microglia in control, early- and late-stage sporadic AD cases; 9th Alzheimerís + Parkinsonís Disease (A+PD) Symposium
Poster 299 - Epigenetic dysregulation of critical gene regulatory elements in AD mice; Australasian Neuroscience Society Annual Scientific Meeting 2016
Poster 341 - Simultaneous alterations in nucleosome positions and DNA methylation predict epigenome-wide changes in Alzheimer's disease; Australasian Neuroscience Society Annual Scientific Meeting 2016
Recapitulation of juvenile-like histone landscape in aged neurons; Australian Dementia Forum 2019

Research Projects

Charting epigenetic reprogramming in Alzheimer's disease mice; The Mason Foundation (ANZCT-Mason Fdn)
Charting epigenetic reprogramming in Alzheimer's disease mice; Dementia Australia Research Foundation Ltd (DARF)

Research Candidate Supervision