Web Access Research Portal

Researcher: Marshall, O (Dr Owen Marshall)

Fields of Research

Biochemistry and Cell Biology
Central Nervous System
Epigenetics (incl. Genome Methylation and Epigenomics)
Regenerative Medicine (incl. Stem Cells and Tissue Engineering)
Neurology and Neuromuscular Diseases
Autonomic Nervous System
Cellular Nervous System
Developmental Genetics (incl. Sex Determination)
Animal Cell and Molecular Biology
Wine Chemistry and Wine Sensory Science

Research Objectives

Expanding Knowledge in the Medical and Health Sciences
Neurodegenerative Disorders Related to Ageing
Expanding Knowledge in the Biological Sciences
Digestive System Disorders
Nervous System and Disorders
Blood Disorders
Inherited Diseases (incl. Gene Therapy)
Control of Animal Pests, Diseases and Exotic Species in Farmland, Arable Cropland and Permanent Cropland Environments

Career Best Publications

Research Publications

Drosophila intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals; Proceedings of the National Academy of Sciences of The United States of America
Active transcription and essential role of RNA polymerase II at the centromere during mitosis; Proceedings of the National Academy of Sciences of The United States of America
Cell-type-specific profiling of gene expression and chromatin binding without cell isolation: assaying RNA Pol II occupancy in neural stem cells; Developmental Cell
Cell-type-specific profiling of protein-DNA interactions without cell isolation using targeted DamID with next-generation sequencing; Nature Protocols
Chromatin state changes during neural development revealed by in vivo cell-type specific profiling; Nature Communications
Contrasting roles of condensin I and condensin II in mitotic chromosome formation; Journal of Cell Science
damidseq_pipeline: an automated pipeline for processing DamID sequencing datasets; Bioinformatics
Graphical Design of Primers with PerlPrimer; PCR Primer Design. Methods in Molecular Biology
Identification of an interaction between SOX9 and HSP70; F E B S Letters: (Federation of European Biochemical Societies)
Molecular mechanisms of SOX9 action; Molecular Genetics and Metabolism
Neocentromeres; The Kinetochore: From Molecular Discoveries to Cancer Therapy
Neocentromeres come of age; PL o S Genetics
Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution; American Journal of Human Genetics
PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR; Bioinformatics
Putative CENP-B paralogues are not present at mammalian centromeres; Chromosoma
The architecture and evolution of cancer neochromosomes; Cancer Cell
Three-dimensional localization of CENP-A suggests a complex higher order structure of centromeric chromatin; Journal of Cell Biology

Research Projects

A genome-wide analysis of the epigenetic control of learning and memory; National Health & Medical Research Council (NHMRC)
Imaging to overcome dementia; Ian Potter Foundation (IPF)

Research Candidate Supervision