Web Access Research Portal

Researcher: Larby, J (Dr Josie Larby)

Fields of Research

Respiratory diseases
Cardiology (incl. cardiovascular diseases)

Research Objectives

Clinical health
Diagnosis of human diseases and conditions
Treatment of human diseases and conditions
Prevention of human diseases and conditions

Career Best Publications

Research Publications

Angiotensin-converting enzyme 2 (ACE2), transmembrane peptidase serine 2 (TMPRSS2), and furin expression increases in the lungs of patients with idiopathic pulmonary fibrosis (IPF) and lymphangioleiomyomatosis (LAM): implications for SARS-CoV-2 (COVID-19) infections; Journal of Clinical Medicine
Chronic obstructive pulmonary disease and lung cancer: underlying pathophysiology and new therapeutic modalities; Drugs
Electronic cigarette aerosol is cytotoxic and increases ACE2 expression on human airway epithelial cells: Implications for SARS-CoV-2 (COVID-19); Journal of Clinical Medicine
Endothelial to mesenchymal transition (EndMT) and vascular remodeling in pulmonary hypertension and idiopathic pulmonary fibrosis; Expert Review of Respiratory Medicine
New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways; Clinical Science
SARS-CoV-2 (COVID-19) adhesion site protein upregulation in small airways, type 2 pneumocytes, and alveolar macrophages of smokers and COPD - possible implications for interstitial fibrosis; International Journal of Chronic Obstructive Pulmonary Disease

Research Projects

Are newly introduced electronic smoking devices safe for smoking cessation and implications for SARS-CoV-2 infection (COVID-19); Clifford Craig Foundation (CCFoundation)
Epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD): role in both airway fibrosis and lung cancer; Clifford Craig Foundation (CCFoundation)
Epithelial mesenchymal transition (EMT) in the lungs and airways in Idiopathic Pulmonary Fibrosis (IPF); Clifford Craig Foundation (CCFoundation)
Establishment of a Tasmanian lung cancer registry: a north and north-west collaborative initiative.; Clifford Craig Foundation (CCFoundation)
Evaluation of new therapeutic targets in idiopathic pulmonary fibrosis (IPF): insights from Australian IPF registry tissue analysis; Clifford Craig Foundation (CCFoundation)
The effect of current and investigational COPD pharmacological agents on the airway Epithelial-Mesenchymal Transition (EMT) process in smokers and COPD; Clifford Craig Foundation (CCFoundation)
To evaluate the role of endothelial to mesenchymal transition in the pathogenesis of idiopathic pulmonary fibrosis and pulmonary hypertension. ; Clifford Craig Foundation (CCFoundation)

Research Candidate Supervision