Web Access Research Portal

Researcher: Kirov, SM (Associate Professor Sylvia Kirov)

Fields of Research

Medical bacteriology
Respiratory diseases
Infectious diseases
Bacteriology
Infectious agents
Cellular immunology
Medical parasitology
Medical infection agents (incl. prions)
Microbiology
Other education
Medical microbiology
Immunology
Pharmaceutical sciences
Haematology
Dermatology
Sensor technology (incl. chemical aspects)
Pathology (excl. oral pathology)
Cell metabolism
Epidemiology
Gene expression (incl. microarray and other genome-wide approaches)

Research Objectives

Clinical health
Other health
Expanding knowledge in the environmental sciences
Food safety
Diagnosis of human diseases and conditions
Other education and training
Disease distribution and transmission (incl. surveillance and response)

Career Best Publications

Aeromonas and Plesiomonas species; Food Microbiology; Fundamentals and Frontiers
Aeromonas flagella (polar and lateral) are enterocyte adhesins that contribute to biofilm formation on surfaces; Infection and Immunity
Bacteria that express lateral flagella enable dissection of the multifunctional roles of flagella in pathogenesis; FEMS Microbiology Letters
Investigation of the role of type IV Aeromonas pilus (Tap) in the pathogenesis of Aeromonas gastrointestinal infection; Infection and Immunity
Lateral flagella and swarming motility in Aeromonas species; Journal of Bacteriology

Research Publications

Aeromonas veronii biotype sobria : adhesion and surface structures; 5th International Aeromonas - Plesiomonas Symposium
Aeromonas; Foodborne Microorganisms of Public Health Significance
Aeromonas spp. - Foodborne Pathogens?; 8th Australian Food Microbiology Conference
Aeromonas 'bundle-forming' type IV pili mediate enterocyte adherence; 6th International Aeromonas/Plesiomonas Symposium
Aeromonas and Plesiomonas species; Food Microbiology : Fundamentals and Frontiers
Aeromonas and Plesiomonas; A compendium of laboratory diagnostic methods for common and unusual pathogens
Aeromonas and Plesiomonas species; Food Microbiology; Fundamentals and Frontiers
Aeromonas cell line adhesion, surface structures and in vivo models of intestinal colonization
Aeromonas filamentous adhesions: an overview; 6th International Aeromonas/Plesiomonas Symposium
Aeromonas flagella (polar and lateral) are enterocyte adhesins that contribute to biofilm formation on surfaces; Infection and Immunity
Aeromonas species; Foodborne Microorganisms of Public Health Significance
Aeromonas spp. possess at least two distinct type IV pilus families; Microbial Pathogenesis
Aeromonas: Recognising the enemy; Today's Life Science
Pseudomonas aeruginosa as a cause of infectious diarrhoea; Epidemiology and Infection
Pseudomonas aeruginosa quorum-sensing systems and host interactions in cystic fibrosis; Annual Meeting for the Australian Society for Microbiology
Pseudomonas aeruginosa: A model for biofilm formation; Pseudomonas. Model Organism, Pathogen, Cell Factory
Rattus norvegicus not a model for Aeromonas-associated gastroenteritis in man; 6th International Aeromonas/Plesiomonas Symposium
Rattus norvegicus: not a model for Aeromonas - associated gastroenteritis in man; FEMS - Immunology and Medical Microbiology
A clonal strain of Pseudomonas aeruginosa in Tasmanian patients with cystic fibrosis; Annual Scientific Meetings of the Australian & New Zealand Society of Respiratory Science and the Thoracic Society of Australia & New Zealand
A clonal strain of Pseudomonas aeruginosa in Tasmanian patients with cystic fibrosis; Thoracic Society of Australia and New Zealand Annual Scientific Conference
Addressing the challenge of persistent lung infection in CF; Australian and New Zealand Cystic Fibrosis Nurses Conference
Addressing the challenges of bacterial biofilm infections; Australian Society for Microbiology Bistate Meeting
Adhesion of Aeromonas sp. to cell lines used as models for intestinal adhesion; Epidemiology and Infection
Anaerobic culture conditions favor biofilm-like phenotypes in Pseudomonas aeruginosa isolates from patients with cystic fibrosis; FEMS Immunology and Medical Microbiology
Bacteria that express lateral flagella enable dissection of the multifunctional roles of flagella in pathogenesis; FEMS Microbiology Letters
Bacterial contamination of stored blood products; 2001 ASM Annual Scientific Meeting
Bacterial cyanogenesis occurs in the cystic fibrosis lung; European Respiratory Journal
Biofilm control by iron manipulation and targeting bacterial persistence mechanisms; The Australian Society for Microbiology
Biofilm differentiation and dispersal in mucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis; Microbiology
Biofilm dispersal and exacerbations of cystic fibrosis lung disease; Pediatric Pulmonology
Biofilm dispersal cells of a cystic fibrosis Pseudomonas aeruginosa isolate exhibit variability in functional traits likely to contribute to persistent infection; FEMS Immunology and Medical Microbiology
Bundle-forming pilus locus of Aeromonas veronii bv. Sobria; Infection and Immunity
Characterisation of a type IV pilus produced by Aeromonas caviae; Journal of Medical Microbiology
Characterisation of biofilm dispersal variants of cystic fibrosis clinical isolates of Pseudomonas aeruginosa; American Society for Microbiology Conference, Biofilms 2007
Characterization of a type IV bundle-forming pilus (SFP) from a gastroenteritis-associated strain of Aeromonas veronii biovar sobria; Microbial Pathogenesis
Clinical significance of seeding dispersal in biofilms; Microbiology
Colonization of streptomycin-treated mice by Aeromonas species; Journal of Diarrhoeal Disease Research
Cystic fibrosis battle's $18,000 boost'
Cystic fibrosis battle's $30,000 boost
Cystic fibrosis sputum contains high concentrations of cyanide; Thoracic Society of Australia and New Zealand Annual Scientific Meeting
Developing models for Aeromonas intestinal colonization; 5th International Aeromonas-Plesiomonas Symposium
Diarrhoea-associated Aeromonas species produce lateral flagella: accessory colonization factors?; 6th International Aeromonas/Plesiomonas Symposium
Differentiation and dispersal of Pseudomonas aeruginosa biofilms; 10th International Congress on Pseudomonas
Distribution of the type IV Aeromonas pilus gene cluster in Aeromonas; Annual Meeting of the Australian Society for Microbiology
Draft genome sequence of the chronic, nonclonal cystic fibrosis isolate Pseudomonas aeruginosa Strain 18A; Genome announcements
Electron microscopic examination of factors influencing the expression of filamentous surface structures on clinical and environmental isolates of Aeromonas veronii biotype sobria; Microbiology and Immunology
Expression and function of the cloned type IV Aeromonas pilus (Tap); 6th International Aeromonas/Plesiomonas Symposium
Functional characterization of type IV pili expressed on diarrhea-associated isolates of Aeromonas species; Infection and Immunity
Functional variability of biofilm dispersal variants of Pseudomonas aeruginosa cystic fibrosis isolate 18A; International Society for Microbial Ecology Conference
Functions of bacterial flagella; Australian Society for Microbiology, Annual Scientific Meeting
Genetic analysis of an Aeromonas type IV pilin gene; Australian Society for Microbiology
Genetics, Evolution, Wild-life Species and Human Health; Australian Society for Microbiology Annual Scientific Meeting
Host response to transmissible Pseudomonas aeruginosa; European Respiratory Journal
Increased airway iron as a potential factor in the persistence of Pseudomonas aeruginosa infection in cystic fibrosis; The European Respiratory Journal
Investigation of the role of type IV Aeromonas pilus (Tap) in the pathogenesis of Aeromonas gastrointestinal infection; Infection and Immunity
Investigations into the role of type IV Aeromonas pilus (Tap) in the pathogenesis of Aeromonas infection; 5th Australian Conference on Molecular Analysis of Bacterial Pathogens
Iron and antibiotic sensitivity of clinical Pseudomonas aeruginosa isolates from CF patients. (The effect of iron concentration on the MICs of ceftazidime, meropenem, and ciprofloxacin for Pseudomonas aeruginosa isolates from CF patients.); 6th Australian and New Zealand Cystic Fibrosis conference
Iron binding compounds impair Pseudomonas aeruginosa growth and biofilm formation, especially under anaerobic conditions; American Society for Microbiology Conference, Biofilms 2007
Iron chelation directed against biofilms as an adjunct to conventional antibiotics; American Journal of Physiology: Lung Cellular and Molecular Physiology
Iron chelation inhibits Pseudomonas aeruginosa biofilm formation; 2006 Annual Scientific Meetings of the Thoracic Society of Australia & New Zealand & the Australian & New Zealand Society of Respiratory Science
Iron influences Pseudomonas aeruginosa biofilm growth; 6th Australian and New Zealand Cystic Fibrosis conference
Iron limitation increases antibiotic sensitivity of P. aeruginosa from CF patients; 2006 Annual Scientific Meetings of the Thoracic Society of Australia & New Zealand & the Australian & New Zealand Society of Respiratory Science
Iron, Pseudomonas aeruginosa and cystic fibrosis; Microbiology
Iron-binding compounds impair Pseudomonas aeruginosa biofilm formation, especially under anaerobic conditions; Journal of Medical Microbiology
Lateral flagella and swarming motility in Aeromonas species; Journal of Bacteriology
Medical Research Week Interview
Meeting the challenge of biofilm-associated infections
Molecular Biology of Bacterial Pathogens; The Molecular Biology of Bacterial Pathogens
Mutation frequency increases during biofilm development and contributes to the formation of biofilm-derived phenotypic variants; American Society for Microbiology
Persistent Pseudomonas aeruginosa lung infection in cystic fibrosis: new insights from the Tasmanian population, Australia; 10th International Congress on Pseudomonas
Pili of diarrhoea-associated Aeromonas species; Fourth Australian conference on molecular analysis of bacterial pathogens
Plasmids and Aeromonas virulence; Australian Society for Microbiology
Plasmids and Aeromonas virulence; FEMS Immunology and Medical Microbiology
Purification and characterisation of type IV pili intestinal colonization factors from diarrhoea-associated Aeromonas species; Australian Society for Microbiology
Rapid detection of bacteria in blood products; Australian Society for Microbiology, Annual Scientific Meeting
Re-evaluation of Aeromonas caviae as a gastrointestinal pathogen; Australian Society for Microbiology
Reducing iron availability is a potential strategy for combating bacterial infection in the cystic fibrosis lung; Asian Pacific Society of Respirology Congress
Session 8; Fourth Australian conference on molecular analysis of bacterial pathogens
Session Chair; 6th Australian Conference on Molecular Analysis of Bacterial Pathogens
Session Chair; 2001 ASM Annual Scientific Meeting
Session Chair: Pili and colonisation; Annual Meeting of the Australian Society for Microbiology
Teaching and research: impossible or essential link?; Microbiology Australia
The identification and human health significance of environmental aeromonads; Health-related water microbiology
The identification and human health significance of environmental aeromonads; Water Science and Technology
The lateral flagellum mediates swarming in Aeromonas species; 2001 ASM Annual Scientific Meeting
The lateral flagellum mediates swarming motility in Aeromonas species. Interactive poster session; 2001 ASM Annual Scientific Meeting
The Microbiology of Cystic Fibrosis; Australian Society for Microbiology Annual Scientific Meeting
The type IV Aeromonas pilus (Tap) gene cluster is widely conserved in Aeromonas species; Microbial pathogenesis
The use of iron chelators to target Pseudomonas aeruginosa; Annual Scientific Meeting for the Australian Society for Microbiology
Type IV pilus adhesins and Aeromonas pathogenesis; Australian Society for Microbiology
Unravelling the complexities of Aeromonas-host mucosal interactions; 2000 Joint Scientific Meeting and Exhibition of the Australian Society for Microbiology and New Zealand Microbiological Society

Research Projects

Aeromonas pili and intestinal colonization; National Health & Medical Research Council (NHMRC)
Aeromondas and their significance as potential pathogens in water; University of Tasmania (UTAS)
Bacterial Detection in Blood Components; Australian Research Council (ARC)
Biohazard Cabinet; National Health & Medical Research Council (NHMRC)
Chronic Pseudomonas aeruginosa Lung Infection in Cystic Fibrosis; Royal Hobart Hospital Research Foundation (RHHRF)
Developing Biofilm Models to Investigate Novel Therapeutic Strategies for Cystic Fibrosis Lung Infection; University of Tasmania (UTAS)
Genetic and Proteomic Analysis of Pseudomonas Aeruginosa Isolates from Tasmanian Cystic Fibrosis Patients; Royal Hobart Hospital Research Foundation (RHHRF)
Iron, Pseudomonas Aeruginosa and Lung Disease in Cystic Fibrosis; National Health & Medical Research Council (NHMRC)
Pathogenesis and public health significance of Aeromonas species; National Health & Medical Research Council (NHMRC)
Pseudomonas Biofilm Growth and Pathogenesis in Cystic Fibrosis; Australian Cystic Fibrosis Research Trust (ACFRT)
Refrigerated centrifuge for immunological and microbiological studies; National Health & Medical Research Council (NHMRC)
Roles of the lateral flagellum in bacterial-host interactions; Royal Hobart Hospital Research Foundation (RHHRF)
Short versus Conventional Course of Oral Corticosteroid for Acute Exacerbations of COPD. A Randomised Controlled Trial. ; Royal Hobart Hospital Research Foundation (RHHRF)
Structure and Function of the Aeromonas Lateral Flagellum; Clifford Craig Medical Research Trust/UTAS (CCMRT/UTAS)
Superspeed Centrifuge.; National Health & Medical Research Council (NHMRC)
Superspeed Refrigerated Centrifuge; Clive & Vera Ramaciotti Foundation (CVRF)
Supplementary funding; University of Tasmania (UTAS)
Targeting Biofilms and Persistent Lung Infection in Cystic Fibrosis to Develop New Therapeutic Interventions; Royal Hobart Hospital Research Foundation (RHHRF)
The role of pili in the pathogenesis of Aeromonas gastroenteritis; Clive & Vera Ramaciotti Foundation (CVRF)
The Roles of Bacterial Surface Structures in Mucosal Colonization and Disease; University of Tasmania (UTAS)
Ultrastructural and genetic analysis of Aeromonas-host interactions; National Health & Medical Research Council (NHMRC)
Whether 3-day course of systematic corticosteroids is as effective as 14-day course in the treatment of acute exacerbations of COPD; Royal Hobart Hospital Research Foundation (RHHRF)

Research Candidate Supervision

A Genetic and Functional Analysis of Type IV Pili Produced by Aeromonas Bacteria
Iron and Pseudomonas aeruginosa Chronic Infection
Methods to detect bacterial contamination of blood products
Pseudomonas aeruginosa in Tasmania