Web Access Research Portal

Researcher: Bye, N (Dr Nicole Bye)

Fields of Research

Central nervous system
Neurology and neuromuscular diseases
Pharmaceutical sciences
Biologically active molecules
Cellular nervous system
Receptors and membrane biology
Basic pharmacology
Cardiology (incl. cardiovascular diseases)
Cellular immunology

Research Objectives

Clinical health
Expanding knowledge in the health sciences
Treatment of human diseases and conditions
Efficacy of medications
Behaviour and health
Human biological preventatives
Expanding knowledge in the biomedical and clinical sciences
Expanding knowledge in the biological sciences
Diagnosis of human diseases and conditions

Career Best Publications

Research Publications

Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain; Journal of Neuroscience Research
Attenuated neurological deficit, cell death and lesion volume in Fas-mutant mice is associated with altered neuroinflammation following traumatic brain injury; Brain research
Attenuation of Microglial Activation with Minocycline Is Not Associated with Changes in Neurogenesis after Focal Traumatic Brain Injury in Adult Mice; Journal of neurotrauma
Coeliac disease patients do not produce antibodies to a common cerebellar epitope; Cerebellum & Ataxias
Dual-modality NIRF-MRI cubosomes and hexosomes: High throughput formulation and in vivo biodistribution; Materials Science & Engineering C-Materials for Biological Applications
Erythropoietin Does Not Alter Serum Profiles of Neuronal and Axonal Biomarkers After Traumatic Brain Injury: Findings From the Australian EPO-TBI Clinical Trial; Critical care medicine
Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor; Journal of Neuroinflammation
Evidence for the recruitment of autophagic vesicles in human brain after stroke; Neurochemistry international
Inflammatory Regulators of Redirected Neural Migration in the Injured Brain; Neurosignals
Neurogenesis and Glial Proliferation Are Stimulated Following Diffuse Traumatic Brain Injury in Adult Rats; Journal of neuroscience research
Nitroxide-loaded hexosomes provide MRI contrast in vivo; Langmuir
Novel short-chain quinones to treat vision loss in a rat model of diabetic retinopathy; International Journal of Molecular Sciences
Nuclear trafficking of Pten after brain injury leads to neuron survival not death; Experimental neurology
Oligodendrocyte birth and death following traumatic brain injury in adult mice; PloS one
Pathological links between traumatic brain injury and dementia: Australian pre-clinical research; Journal of Neurotrauma
Post-Traumatic Hypoxia Is Associated with Prolonged Cerebral Cytokine Production, Higher Serum Biomarker Levels, and Poor Outcome in Patients with Severe Traumatic Brain Injury; Journal of Neurotrauma
Rho kinase inhibition following traumatic brain injury in mice promotes functional improvement and acute neuron survival but has little effect on neurogenesis, glial responses or neuroinflammation; Experimental Neurology
Suppressor of cytokine Signaling-2 (SOCS2) regulates the microglial response and improves functional outcome after traumatic brain injury in mice; PloS One
The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments; Acta Neuropathologica
The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury; PLoS one

Research Projects

Acquisition of a VS200 Research Slide Scanner for the College of Health and Medicine; Ian Potter Foundation (IPF)
Investigating the anti-inflammatory effect of a non-anticoagulant molecule of heparin following experimental traumatic brain injury; Royal Hobart Hospital Research Foundation (RHHRF)

Research Candidate Supervision