Fields of Research

Cardiology (incl. cardiovascular diseases)
Health economics
Preventative health care
Basic pharmacology
Major global burdens of disease
Other health sciences
Cancer therapy (excl. chemotherapy and radiation therapy)
Cancer genetics
Aged health care
Health promotion
Genetics
Clinical sciences
Economic models and forecasting
Occupational epidemiology
Translational and applied bioinformatics
Toxicology (incl. clinical toxicology)
Traditional Chinese medicine and treatments
Predictive and prognostic markers
Environmental epidemiology
Cell physiology
Pollution and contamination
Patient safety
Disease surveillance
Epidemiology
Clinical pharmacy and pharmacy practice

Research Objectives

Efficacy of medications
Treatment of human diseases and conditions
Clinical health
Prevention of human diseases and conditions
Health related to ageing
Expanding knowledge in the biomedical and clinical sciences
Diagnosis of human diseases and conditions
Other health
Air quality
Preventive medicine
Primary care
Health policy evaluation
Behaviour and health
Health education and promotion

Career Best Publications

Association of statin use with disability-free survival and cardiovascular disease among healthy older adults; Journal of the American College of Cardiology
Effect of statin therapy on cognitive decline and incident dementia in older adults; Journal of the American College of Cardiology

Research Publications

Antihypertensive drug class in combination with lipid lowering treatment for primary prevention of cardiovascular disease in the elderly; Heart and Lung
Association between solid fuel combustion and diabetes mellitus: a systematic review and meta‑analysis; Environmental science and pollution research international
Association between statin use and progression of arterial stiffness among adults with high atherosclerotic risk; JAMA Network Open
Association of apatinib and breast cancer: A systematic review and meta-analysis; Surgical Oncology
Association of statin use with cardiovascular outcomes by coronary calcium: MESA; JACC: Cardiovascular Imaging
Association of statin use with disability-free survival and cardiovascular disease among healthy older adults; Journal of the American College of Cardiology
Association of urinary or blood heavy metals and mortality from all causes, cardiovascular disease, and cancer in the general population: a systematic review and meta‑analysis of cohort studies; Environmental Science and Pollution Research: International
Autophagy, a process within reperfusion injury: an update; International Journal of Clinical and Experimental Pathology
Bioequivalence and pharmacokinetic evaluation of two oral formulations of regorafenib: An open-label, randomised, single-dose, two-period, two-way crossover clinical trial in healthy Chinese volunteers under fasting and fed conditions; Drug Design, Development and Therapy
CCNB2 expression correlates with worse outcomes in breast cancer patients: a pooled analysis; Women & Health
Clinicopathologic and prognostic roles of circular RNA plasmacytoma variant translocation 1 in various cancers; Expert Review of Molecular Diagnostics
Comparison of statins for primary prevention of cardiovascular disease and persistent physical disability in older adults; European Journal of Clinical Pharmacology
Concerns related to the nocebo effect; The Lancet
Cost-effectiveness analysis of tislelizumab, nivolumab and docetaxel as second- and third-line for advanced or metastatic non-small cell lung cancer in China; Frontiers in Pharmacology
Cost-effectiveness of Bevacizumab Biosimilar LY01008 combined with chemotherapy as first-line treatment for chinese patients with advanced or recurrent nonsquamous non-small cell lung cancer; Frontiers in Pharmacology
Cost-effectiveness of domestic PD-1 inhibitor Camrelizumab combined with chemotherapy in the first-line treatment of advanced nonsquamous non–small-cell lung cancer in China; Frontiers in Pharmacology
Cost-effectiveness of ensartinib, crizotinib, ceritinib, alectinib, brigatinib and lorlatinib in patients with anaplastic lymphoma kinase-positive non-small cell lung cancer in China; Frontiers in Public Health
Cost-effectiveness of pembrolizumab plus chemotherapy versus pembrolizumab monotherapy in metastatic non-squamous and squamous NSCLC patients With PD-L1 expression ≥ 50%; Frontiers in Pharmacology
Diagnostic value, prognostic value, and immune infiltration of LOX family members in liver cancer: bioinformatic analysis; Frontiers in Oncology
Does aspirin have an effect on risk of death in patients with COVID-19? A meta-analysis; European Journal of Clinical Pharmacology
Does aspirin prevent incident heart failure in healthy older adults? Examining the evidence from the ASPREE trial; Circulation: Heart Failure
Effect of statin therapy on cognitive decline and incident dementia in older adults; Journal of the American College of Cardiology
Efficacy and Safety of Direct Oral Anticoagulants in Patients With Mitral Stenosis; Journal of the American College of Cardiology
Expression and prognostic value of MCM family genes in osteosarcoma; Frontiers in Molecular Biosciences
First-line ICI monotherapies for advanced non-small-cell lung cancer patients with PD-L1 of at least 50%: A cost-effectiveness analysis; Frontiers in Pharmacology
Gene expression microarray data identify hub genes involved in Osteoarthritis; Frontiers in Genetics
High spicy food intake may increase the risk of esophageal cancer: a meta-analysis and systematic review; Nutrition Research
Identification and verification of potential biomarkers in gastric cancer by integrated bioinformatic analysis; Frontiers in Genetics
Impact of blood lipids on 10-year cardiovascular risk in individuals without dyslipidemia and with low risk factor burden; Mayo Clinic Proceedings
Is metformin use associated with a reduced risk of oesophageal cancer? A systematic review and meta-analysis; Postgraduate Medical Journal
Letter by Zhou et al Regarding Article, “Statin Toxicity: Mechanistic Insights and Clinical Implications”; Circulation Research
Letter to the Editor; JAMA Internal Medicine
Lung cancer screening with low-dose computed tomography: National expenditures and cost-effectiveness; Frontiers in Public Health
Older participant perspectives on permanent study drug discontinuation in an ongoing primary prevention trial of statins; European Journal of Clinical Pharmacology
PD-L1 test-based strategy with Nivolumab as the second-line treatment in advanced NSCLC: A cost-effectiveness analysis in China; Frontiers in Oncology
Prognostic significance of long non-coding RNA five prime to XIST in various cancers; BMC Cancer
Renshen Baidu Powder attenuated intestinal inflammation and apoptosis in ulcerative colitis rats through the inhibition of PI3K/AKT/NF- κ B signaling pathway; Evidence-Based Complementary and Alternative Medicine
REPLY: Statin Therapy on Cognitive Decline and Incident Dementia; Journal of the American College of Cardiology
Safety of ceasing aspirin used without a clinical indication after age 70 years: a subgroup analysis of the ASPREE randomized trial; Annals of Internal Medicine
Sauchinone augments cardiomyocyte viability by enhancing autophagy proteins -PI3K, ERK(1/2), AMPK and Beclin-1 during early ischemia-reperfusion injury in vitro; American Journal of Translational Research
Short-term exposure to ambient ozone and cardiovascular mortality in China: a systematic review and meta-analysis; International Journal of Environmental Health Research
Statin Therapy on Cognitive Decline and Incident Dementia; Journal American College of Cardiology
Statin-associated muscle symptoms (SAMS) in primary prevention for cardiovascular disease in older adults: a protocol for a systematic review and meta-analysis of randomised controlled trials; BMJ Open
Statins for Primary Prevention of Cardiovascular Disease; Annals of Internal Medicine
The cost-effectiveness of tislelizumab plus chemotherapy for locally advanced or metastatic nonsquamous non-small cell lung cancer; Frontiers in Pharmacology
The efficacy and safety of acupuncture for treating osteoporotic vertebral compression fracture- (OVCF-) induced pain: A systematic review and meta-analysis of randomized clinical trials; Evidence-Based Complementary and Alternative Medicine
The safety and tolerability of statin therapy in primary prevention in older adults: a systematic review and meta-analysis; Drugs and Aging
The Value of Coronary Artery Calcium in Statin-Treated Patients; Journal of the American College of Cardiology
Uncovering the mechanism of Huanglian-Wuzhuyu herb pair in treating nonalcoholic steatohepatitis based on network pharmacology and experimental validation; Journal of Ethnopharmacology

Research Projects

Understanding the impact of serum lipid profiles on disability-free survival, cardiovascular disease, and other major geriatric-related diseases in the healthy elderly; Royal Australian College of General Practitioners (RACGP)

Research Candidate Supervision