Web Access Research Portal

Researcher: Zhou, Z (Dr Zhen Zhou)

Fields of Research

Cardiology (incl. cardiovascular diseases)
Preventative health care
Health economics
Major global burdens of disease
Other health sciences
Aged health care
Toxicology (incl. clinical toxicology)
Patient safety
Occupational epidemiology
Economic models and forecasting
Clinical sciences
Basic pharmacology
Health promotion
Genetics
Traditional Chinese medicine and treatments
Cell physiology
Clinical pharmacy and pharmacy practice

Research Objectives

Efficacy of medications
Clinical health
Treatment of human diseases and conditions
Health related to ageing
Diagnosis of human diseases and conditions
Preventive medicine
Other health
Primary care
Prevention of human diseases and conditions
Air quality
Behaviour and health

Career Best Publications

Association of statin use with disability-free survival and cardiovascular disease among healthy older adults; Journal of the American College of Cardiology
Effect of statin therapy on cognitive decline and incident dementia in older adults; Journal of the American College of Cardiology

Research Publications

Antihypertensive drug class in combination with lipid lowering treatment for primary prevention of cardiovascular disease in the elderly; Heart and Lung
Association of statin use with cardiovascular outcomes by coronary calcium: MESA; JACC: Cardiovascular Imaging
Association of statin use with disability-free survival and cardiovascular disease among healthy older adults; Journal of the American College of Cardiology
Autophagy, a process within reperfusion injury: an update; International Journal of Clinical and Experimental Pathology
Bioequivalence and pharmacokinetic evaluation of two oral formulations of regorafenib: An open-label, randomised, single-dose, two-period, two-way crossover clinical trial in healthy Chinese volunteers under fasting and fed conditions; Drug Design, Development and Therapy
Clinicopathologic and prognostic roles of circular RNA plasmacytoma variant translocation 1 in various cancers; Expert Review of Molecular Diagnostics
Comparison of statins for primary prevention of cardiovascular disease and persistent physical disability in older adults; European Journal of Clinical Pharmacology
Concerns related to the nocebo effect; The Lancet
Cost-effectiveness of Bevacizumab Biosimilar LY01008 combined with chemotherapy as first-line treatment for chinese patients with advanced or recurrent nonsquamous non-small cell lung cancer; Frontiers in Pharmacology
Cost-effectiveness of domestic PD-1 inhibitor Camrelizumab combined with chemotherapy in the first-line treatment of advanced nonsquamous non–small-cell lung cancer in China; Frontiers in Pharmacology
Cost-effectiveness of pembrolizumab plus chemotherapy versus pembrolizumab monotherapy in metastatic non-squamous and squamous NSCLC patients With PD-L1 expression ≥ 50%; Frontiers in Pharmacology
Diagnostic value, prognostic value, and immune infiltration of LOX family members in liver cancer: bioinformatic analysis; Frontiers in Oncology
Does aspirin prevent incident heart failure in healthy older adults? Examining the evidence from the ASPREE trial; Circulation: Heart Failure
Effect of statin therapy on cognitive decline and incident dementia in older adults; Journal of the American College of Cardiology
Efficacy and Safety of Direct Oral Anticoagulants in Patients With Mitral Stenosis; Journal of the American College of Cardiology
Expression and prognostic value of MCM family genes in osteosarcoma; Frontiers in Molecular Biosciences
First-line ICI monotherapies for advanced non-small-cell lung cancer patients with PD-L1 of at least 50%: A cost-effectiveness analysis; Frontiers in Pharmacology
Is metformin use associated with a reduced risk of oesophageal cancer? A systematic review and meta-analysis; Postgraduate Medical Journal
Letter by Zhou et al Regarding Article, “Statin Toxicity: Mechanistic Insights and Clinical Implications”; Circulation Research
Letter to the Editor; JAMA Internal Medicine
Older participant perspectives on permanent study drug discontinuation in an ongoing primary prevention trial of statins; European Journal of Clinical Pharmacology
PD-L1 test-based strategy with Nivolumab as the second-line treatment in advanced NSCLC: A cost-effectiveness analysis in China; Frontiers in Oncology
Prognostic significance of long non-coding RNA five prime to XIST in various cancers; BMC Cancer
REPLY: Statin Therapy on Cognitive Decline and Incident Dementia; Journal of the American College of Cardiology
Safety of ceasing aspirin used without a clinical indication after age 70 years: a subgroup analysis of the ASPREE randomized trial; Annals of Internal Medicine
Sauchinone augments cardiomyocyte viability by enhancing autophagy proteins -PI3K, ERK(1/2), AMPK and Beclin-1 during early ischemia-reperfusion injury in vitro; American Journal of Translational Research
Short-term exposure to ambient ozone and cardiovascular mortality in China: a systematic review and meta-analysis; International Journal of Environmental Health Research
Statin Therapy on Cognitive Decline and Incident Dementia; Journal American College of Cardiology
Statin-associated muscle symptoms (SAMS) in primary prevention for cardiovascular disease in older adults: a protocol for a systematic review and meta-analysis of randomised controlled trials; BMJ Open
Statins for Primary Prevention of Cardiovascular Disease; Annals of Internal Medicine
The efficacy and safety of acupuncture for treating osteoporotic vertebral compression fracture- (OVCF-) induced pain: A systematic review and meta-analysis of randomized clinical trials; Evidence-Based Complementary and Alternative Medicine
The safety and tolerability of statin therapy in primary prevention in older adults: a systematic review and meta-analysis; Drugs and Aging
The Value of Coronary Artery Calcium in Statin-Treated Patients; Journal of the American College of Cardiology

Research Projects

Understanding the impact of serum lipid profiles on disability-free survival, cardiovascular disease, and other major geriatric-related diseases in the healthy elderly; Royal Australian College of General Practitioners (RACGP)

Research Candidate Supervision