Web Access Research Portal

Researcher: Perera, AP (Mrs Agampodi Perera)

Fields of Research

Medical genetics (excl. cancer genetics)
Gastroenterology and hepatology
Nutritional science
Cellular immunology
Medical bacteriology
Analytical chemistry
Infectious diseases
Genetic immunology
Pharmaceutical sciences
Cancer diagnosis
Optical technology
Cancer cell biology
Food properties (incl. characteristics and health benefits)
Innate immunity

Research Objectives

Clinical health
Prevention of human diseases and conditions
Diagnosis of human diseases and conditions
Expanding knowledge in the chemical sciences
Plant extracts

Career Best Publications

Research Publications

Ccr6 Deficiency attenuates spontaneous chronic colitis in Winnie; Gastrointestinal Disorders
A human origin strain Lactobacillus acidophilus DDS-1 exhibits superior in vitro probiotic efficacy in comparison to plant or dairy origin probiotics; International Journal of Medical Sciences
A rapid amplification/detection assay for analysis of Mycobacterium tuberculosis using an isothermal and silicon bio-photonic sensor complex; Biosensors & bioelectronics
Comparison of candidate materials for a synthetic osteo-odonto keratoprosthesis device; Investigative Ophthalmology and Visual Science
Does NLRP3 inflammasome and aryl hydrocarbon receptor play an interlinked role in bowel inflammation and colitis-associated colorectal cancer?; Molecules
Hevin plays a pivotal role in corneal wound healing; PLoS One
Idebenone protects against spontaneous chronic murine colitis by alleviating endoplasmic reticulum stress and inflammatory response; Biomedicines
Label-free DNA sensor for detection of bladder cancer biomarkers in urine; Sensors and Actuators - B: Chemical
Label-free methylation specific sensor based on silicon microring resonators for detection and quantification of DNA methylation biomarkers in bladder cancer; Sensors and Actuators - B: Chemical
Label-free, PCR-free chip-based detection of telomerase activity in bladder cancer cells; Biosensors and Bioelectronics
Lactobacillus acidophilus DDS-1 modulates intestinal-specific microbiota, short-chain fatty acid and immunological profiles in aging mice; Nutrients
Mach–Zehnder interferometer (MZI) point-of-care system for rapid multiplexed detection of microRNAs in human urine specimens; Biosensors and Bioelectronics
Major Role of NLRP3 Inflammasome in Colitis Progression; International Congress of Immunology (ICI)
MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice; Scientific Reports
Modulating the microbiome and immune responses using whole plant fibre in synbiotic combination with fibre-digesting probiotic attenuates chronic colonic inflammation in spontaneous colitic mice model of IBD; Nutrients
NLRP3 inflammasome in colitis and colitis-associated colorectal cancer; Mammalian Genome
NLRP3 inhibitors as potential therapeutic agents for treatment of inflammatory bowel disease; Current Pharmaceutical Design
Oxidation of cyclohexene in a simple capillary-microreactor; International Journal of Nanoscience
Plasmonic nanohole arrays for monitoring growth of bacteria and antibiotic susceptibility test; Sensors and Actuators - B: Chemical
Probiotic Bacillus coagulans MTCC 5856 spores exhibit excellent in-vitro functional efficacy in simulated gastric survival, mucosal adhesion and immunomodulation; Journal of Functional Foods
Real-time, label-free isothermal solid-phase amplification/detection (ISAD) device for rapid detection of genetic alteration in cancers; Lab on A Chip
Solid phase nucleic acid extraction technique in a microfluidic chip using a novel non-chaotropic agent: dimethyl adipimidate; Lab on A Chip
Synbiotic supplementation containing whole plant sugar cane Fibre and probiotic spores potentiates protective synergistic effects in mouse model of IBD; Nutrients
Synbiotic supplementation with prebiotic green banana resistant starch and probiotic Bacillus coagulans spores ameliorates gut inflammation in mouse model of inflammatory bowel diseases; European Journal of Nutrition

Research Projects

Research Candidate Supervision