Web Access Research Portal

Researcher: Sonda, S (Dr Sabrina Sonda)

Fields of Research

Signal Transduction
Cell Development, Proliferation and Death
Cell Metabolism
Cell Physiology
Gene Expression (incl. Microarray and other genome-wide approaches)

Research Objectives

Digestive System Disorders
Skeletal System and Disorders (incl. Arthritis)

Career Best Publications

Research Publications

1-Deoxysphingolipid-induced neurotoxicity involves N-methyl-d-aspartate receptor signaling; Neuropharmacology
Class I histone deacetylase inhibition improves pancreatitis outcome by limiting leukocyte recruitment and acinar-to-ductal metaplasia; British journal of pharmacology
Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation; Gut: An International Journal of Gastroenterology and Hepatology
Enhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of infammation; Scientific Reports
Ibuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells upon inflammatory injury and mitogenic stimulation; British Journal of Pharmacology
Inhibition of Class I histone deacetylases abrogates tumor growth factor β expression and development of fibrosis during chronic pancreatitis; Molecular pharmacology
Local hyperthyroidism promotes pancreatic acinar cell proliferation during acute pancreatitis; Journal of Pathology
Targeting the zinc transporter ZIP7 in the treatment of insulin resistance and type 2 diabetes; Nutrients
The zinc transporter Zip7 is downregulated in skeletal muscle of insulin-resistant cells and in mice fed a high-fat diet; Cells

Research Projects

Zinc activation of enzymes responsible for insulin signalling and glucose homeostasis in type 2 diabetes; Clifford Craig Foundation (CCFoundation)

Research Candidate Supervision