Web Access Research Portal

Researcher: Stankovich, J (Dr Jim Stankovich)

Fields of Research

Central Nervous System
Medical Genetics (excl. Cancer Genetics)
Epidemiology
Cancer Genetics
Neurology and Neuromuscular Diseases
Genetics
Oncology and Carcinogenesis
Genomics
Ophthalmology
Rheumatology and Arthritis
Haematology
Quantitative Genetics (incl. Disease and Trait Mapping Genetics)
Neurogenetics
Nephrology and Urology
Preventive Medicine
Australian History (excl. Aboriginal and Torres Strait Islander History)
Health and Community Services
Gene Expression (incl. Microarray and other genome-wide approaches)
Clinical Pharmacology and Therapeutics
Clinical Chemistry (diagnostics)
Public Health and Health Services
Cardiology (incl. Cardiovascular Diseases)
Clinical Sciences
Endocrinology
Immunological and Bioassay Methods
Population, Ecological and Evolutionary Genetics
Clinical Nursing: Tertiary (Rehabilitative)
Probability Theory
Biological Mathematics
Colloid and Surface Chemistry
Medical and Health Sciences
Cellular Immunology
Cancer Diagnosis
Immunogenetics (incl. Genetic Immunology)
Psychiatry (incl. Psychotherapy)
Haematological Tumours
Autoimmunity
Cancer Cell Biology
Clinical Pharmacy and Pharmacy Practice
Genome Structure and Regulation
Geriatrics and Gerontology
Genetic Immunology
Solid Tumours
Simulation and Modelling
Exercise Physiology
Motor Control
Medical Biochemistry and Metabolomics
Applied Statistics

Research Objectives

Nervous System and Disorders
Cancer and Related Disorders
Inherited Diseases (incl. Gene Therapy)
Skeletal System and Disorders (incl. Arthritis)
Preventive Medicine
Hearing, Vision, Speech and Their Disorders
Immune System and Allergy
Men's Health
Evaluation of Health Outcomes
Cardiovascular System and Diseases
Disease Distribution and Transmission (incl. Surveillance and Response)
Diabetes
Urogenital System and Disorders
Health and Support Services
Blood Disorders
Human Diagnostics
Child Health
Health
Expanding Knowledge through Studies of Human Society
Expanding Knowledge in History and Archaeology
Aboriginal and Torres Strait Islander Health - Health Status and Outcomes
Defence
Expanding Knowledge in the Chemical Sciences
Environmental Health
Expanding Knowledge in Economics
Mental Health
Infectious Diseases
Aboriginal and Torres Strait Islander Health - Health System Performance (incl. Effectiveness of Interventions)
Skin and Related Disorders
Dental Health
Aboriginal and Torres Strait Islander Health - Determinants of Health
Expanding Knowledge in the Medical and Health Sciences

Career Best Publications

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis; PLoS ONE
Evidence for a common genetic aetiology in high-risk families with multiple haematological malignancy subtypes ; British Journal of Haematology
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20; Nature Genetics
Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand ; Human Genetics
Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease; European Journal of Human Genetics
Identity-by-Descent Mapping to Detect Rare Variants Conferring Susceptibility to Multiple Sclerosis; PLoS ONE
Multiple Sclerosis Susceptibility-Associated SNPs Do Not Influence Disease Severity Measures in a Cohort of Australian MS Patients; P L o S One
Multipoint approximations of identity-by-descent probabilities for accurate linkage analysis of distantly related individuals; American Journal of Human Genetics
On the utility of data from the International HapMap Project for Australian association studies; Human Genetics
Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians; Genes and Immunity
The advantages of dense marker sets for linkage analysis with very large families; Human Genetics

Research Publications

A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis; PLoS One
A Clinical Screening Tool Identifies Autoimmune Diabetes in Adults; Diabetes Care
A Cross Sectional Study of the Association Between Sex, Smoking, and other Lifestyle Factors and Osteoarthritis of the Hand; Journal of Rheumatology
A DNA resequencing array for genes involved in Parkinson's disease; Parkinsonism and related disorders
A genome-wide association study in progressive multiple sclerosis; Multiple Sclerosis
A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis; PLoS ONE
A potentiation of the adverse effect of human leukocyte antigen-DR15 on the risk of multiple sclerosis by low infant sibling exposure: a population based case-control study; 13th Annnual Meeting of the Amer-Comm-for-Treatment-and-Res-in-Multiple-Sclerosis
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis; Human Molecular Genetics
A role for integrin alpha 2 in familial prostate cancer susceptibility; kConFab: Familial Aspects of Cancer: Research and Practice
A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in Multiple Sclerosis ; P L o S One
An Assessment and Planning Unit reduces length of stay in hospital for General Medical patients
An Immunochip Based Interrogation of Scleroderma Susceptibility Variants; Internal Medicine Journal, Vol 42
An Immunochip-Based Interrogation of Scleroderma Susceptibility Variants; Rheumatology, , Vol 51
An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3; Arthritis Research & Therapy
Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class 1 region in Tasmanian MS patients; Immunogenetics
Anticipation in familial hematologic malignancies; Blood
Apolipoprotein E4 genotype does not influence multiple sclerosis phenotype, severity, cognition or brain atrophy in a large Australian cohort; 13th Annnual Meeting of the Amer-Comm-for-Treatment-and-Res-in-Multiple-Sclerosis
Apolipoprotein genotype does not influence MS severity, cognition, or brain atrophy; Neurology
Array-Based Gene Discovery with Three Unrelated Subjects Shows SCARB2/LIMP-2 Deficiency Causes Myoclonus Epilepsy and Glomerulosclerosis; American Journal of Human Genetics
Association of ACE Gene Polymorphism with Genetic Susceptibility to Systemic Lupus Erythematosus in a Chinese Population: A Family-based Association Study; The Journal of Rheumatology
Associations between HLA DRB1 Alleles and Autoantibodies in Systemic Sclerosis; Internal Medicine Journal, Vol 44
Associations between the genetic polymorphisms of MTHFR and outcomes of methotrexate treatment in rheumatoid arthritis; Clinical and Experimental Rheumatology
Chronic kidney disease in Australian general practice: its prevalence, and associated patient characteristics and comorbidities; 2017 Annual Scientific meeting Australian and New Zealand Society of Nephrology
Common variants at 12q14 and 12q24 are associated with hippocampal volume; Nature Genetics
Common variation in the MOG gene influences transcript splicing in humans; Journal of Neuroimmunology
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips; BMC Bioinformatics
Confirmation of the Adult-Onset Primary Open Angle Glaucoma Locus GLC1B at 2cen-q13 in an Australian Family; Ophthalmologica
CTLA-4 and multiple sclerosis: The A49G single nucleotide polymorphism shows no association with multiple sclerosis in a Southern Australian population; Journal of Neuroimmunology
Cutaneous Melanin Density of Caucasians Measured by Spectrophotometry and Risk of Malignant Melanoma, Basal Cell Carcinoma, and Squamous Cell Carcinoma of the Skin; American Journal of Epidemiology
Detecting genome wide haplotype sharing using SNP or microsatellite haplotype data; Human Genetics
Does the Addition of Information on Genotype Improve Prediction of the Risk of Melanoma and Nonmelanoma Skin Cancer beyond That Obtained from Skin Phenotype?; American Journal of Epidemiology
Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis; Human Molecular Genetics
Evidence for a common genetic aetiology in high-risk families with multiple haematological malignancy subtypes ; British Journal of Haematology
Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis; Human Genetics
Familial Haematological Malignancies; GeneMappers
Familial Haematological malignancies: The Tasmanian experience; Haematology Society of Australia and New Zealand, Australia and New Zealand Society for Blood Transfusion & Australasian Society for Thrombosis and Homeostasis
Familial, structural, and environmental correlates of MRI-defined bone marrow lesions: a sibpair study; Arthritis Research & Therapy
Fine mapping of multiple sclerosis susceptibility genes provides evidence of allelic heterogeneity at the IL2RA locus; Journal of Neuroimmunology
Fine-mapping the genetic association of the major histocompatibility complex in Multiple Sclerosis: HLA and non-HLA effects; PLoS Genetics
Four year trends in emergency department presentations in Tasmania; Emergency Tasmanian Conference 2016
Genes implicated in multiple sclerosis pathogenesis fromconsilience of genotyping and expression profiles in relapse and remission; BMC Medical Genetics
Genetic Epidemiology in Tasmania; Australasian Epidemiologist
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis; Nature
Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis; Annals of Neurology
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20; Nature Genetics
Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand ; Human Genetics
Genome-Wide Meta-Analysis Identifies Novel Multiple Sclerosis Susceptibility Loci; Annals of Neurology
Growing Incomes, Growing People In Nineteenth-Century Tasmania; Australian Economic History Review
Heritability and shared environment estimates for myopia and associated ocular biometric traits: the Genes in Myopia (GEM) family study; Human Genetics
Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognition ; Multiple Sclerosis
HLA-DRB1 associations with disease susceptibility and clinical course in Australians with multiple sclerosis; Tissue Antigens
Human Leukocyte Antigen-DR15, Low Infant Sibling Exposure and Multiple Sclerosis: Gene-Environment Interaction; Annals of Neurology
Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease; European Journal of Human Genetics
Identification of Susceptibility Genes for Haematological Maligancies; GeneMappers
Identifying nineteenth century genealogical links from genotypes; Human Genetics
Identity-by-Descent Mapping to Detect Rare Variants Conferring Susceptibility to Multiple Sclerosis; PLoS ONE
Incidence and prevalence of NMOSD in Australia and New Zealand; Journal of Neurology, Neurosurgery and Psychiatry
Individual and Joint Action of Environmental Factors and Risk of MS
Investigating a cluster of vulvar cancer in young women: a cross-sectional study of genital human papillomavirus prevalence; BMC Infectious Diseases
Investigation of albinism genes in congenital esotropia; Molecular Vision
Investigation of chromosome 2q in osteoarthritis of the hand: no significant linkage in a Tasmanian population; Annals of the Rheumatic Diseases
Linkage analysis of a large Tasmanian haematological cancer family; GeneMappers
Linkage analysis of a second large prostate cancer family from southern Tasmania, Australia; American Society of Human Genetics Conference
Linkage Replication of the MYP12 Locus in Common Myopia; Investigative Ophthalmology and Vision Science
Linkage to 10q22 for maximum intraocular pressure and 1p32 for maximum cup-to-disc ratio in an extended primary open-angle glaucoma pedigree; Investigative Ophthalmology & Visual Science
Measuring environmental factors can enhance the search for disease causing genes?; Journal of Epidemiology and Community Health
Melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis; Neurology
MicroRNAs miR-17 and miR-20a Inhibit T Cell Activation Genes and Are Under-Expressed in MS Whole Blood; P L o S One
Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry; Journal of Photochemistry and Photobiology, B: Biology
Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data; Genome Medicine
Modeling the structure of charged binary colloidal dispersions; Langmuir
Modelling genetic susceptibility to multiple sclerosis with family data; Neuroepidemiology
Multiple Sclerosis Susceptibility-Associated SNPs Do Not Influence Disease Severity Measures in a Cohort of Australian MS Patients; P L o S One
Multiple Sclerosis: a haplotype association study; Novartis Foundations Symposium
Multipoint approximations of identity-by-descent probabilities for accurate linkage analysis of distantly related individuals; American Journal of Human Genetics
Mutations in a Novel Gene, NHS, Cause the Pleiotropic Effects of Nance-Horan Syndrome, Including Severe Congenital Cataract, Dental Anomalies, and Mental Retardation; American Journal of Human Genetics
Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls; American Journal of Human Genetics: A Record of Research, Review and Bibliographic Material Relating to Heredity in Man
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis; Human Molecular Genetics
On the utility of data from the International HapMap Project for Australian association studies; Human Genetics
Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction ; Multiple Sclerosis
Planning for the future: emergency department presentation patterns in Tasmania, Australia; International Emergency Nursing
Polymorphisms in the Receptor Tyrosine Kinase MERTK Gene Are Associated with Multiple Sclerosis Susceptibility; PL o S One
Prison and the colonial family; The History of the Family
Prolonged ED access block impacts on patient outcomes in a large regional hospital; 9th Health Services and Policy Research Conference, Melbourne, 2015
Prostate Cancer Sun Exposure and Genes Modifying Risk; 11th International Congress of Human Genetics
Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians; Genes and Immunity
Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes; Human Molecular Genetics
Saliva-Derived DNA Performs Well in Large-Scale, High-Density Single-Nucleotide Polymorphism Microarray Studies; Cancer Epidemiology, Biomarkers and Prevention
Searching for rare variants conferring susceptibility to multiple sclerosis; Progress in MS Research Conference
Sequence variants of α-methylacyl-CoA racemase are associated with prostate cancer risk: A replication study in an ethnically homogeneous population; The Prostate
SNP mapping and candidate gene sequencing in the class 1 region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians; Tissue Antigens
Syndrome X in 8-y-old Australian children: stronger associations with current body fatness than with infant size or growth; International Journal of Obesity
The advantages of dense marker sets for linkage analysis with very large families; Human Genetics
The apolipoprotein epsilon 4 gene is associated with elevated risk of normal tension glaucoma; Molecular Vision
The application of a population based ascertainment correction for the variance components analysis of quantitative traits in a single extended pedigree; 5th Australasian Human Gene Mapping Conference Incorporating the 9th Australian Twin Registry Conference
The association between hormonal and reproductive factors and hand osteoarthritis; Maturitas
The genetic contribution and relevance of knee cartilage defects: Case-control and sib-pair studies; Journal of Rheumatology
The genetic contribution to longitudinal changes in knee structural and muscle strength: A Sibpair Study; Arthritis & Rheumatism
The Genetic Contribution to Muscle Strength, Knee Pain, Cartilage Volume, Bone Size, and Radiographic Osteoarthritis; Arthritis and Rheumatism
The HLA-DR2 genotype does not affect MS severity, cognition or brain atrophy; 25th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis
The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis ; Human Molecular Genetics
The Tasmanian familial leukaemia and lymphoma research study; Haematology Society of Australia and New Zealand, Australia and New Zealand Society for Blood Transfusion & Australasian Society for Thrombosis and Homeostasis
The Tasmanian familial leukaemia and lymphoma research study; GeneMappers
The use of computer-assisted-telephone-interviewing to diagnose seizures, epilepsy and Idiopathic Generalized Epilepsy; Epilepsy Research
The Varied Mechanisms of Vitamin D in the Onset and Clinical Course of MS: Potential Roles in Modulating Other Etiological Pathways
Tonography demonstrates reduced facility of outflow of aqueous humour in myocilin mutation carriers; Journal of Glaucoma
Trends in diabetes management practices of patients from an Australian insulin-treated diabetes register; Diabetic Medicine
Using genetic advances to investigate diabetes in Australia
Using normal variation in neuroanatomic traits to identify genes and pathways influencing disease: a joint linkage and association analysis of brain lesions; 8th GeneMappers Conference
Variants of ST8SIA1 Are Associated with Risk of Developing Multiple Sclerosis; PLoS One
Vitamin D status: Multifactorial contribution of environment, genes and other factors in healthy Australian adults across a latitude gradient; Journal of Steroid Biochemistry and Molecular Biology
Whole genome sequencing of CLL case; GeneMappers

Research Projects

A course in computational and statistical skills for medical genetics researchers; Department of Foreign Affairs and Trade (DFAT)
An ENU mutagenesis program to identify candidate targets for host-directed therapy against malaria; National Health & Medical Research Council (NHMRC)
Cellular genomic approach to the pathogenesis of multiple sclerosis; Australian Research Council (ARC)
Elucidation of the role of a novel susceptibility gene in prostate cancer; Royal Hobart Hospital Research Foundation (RHHRF)
Elucidation of the role of a novel susceptibility gene in prostate cancer; Cancer Council of Tasmania (CCT)
Elucidation of the role of the integrin alpha 2 gene (ITGA2) in prostate cancer; Cancer Council of Tasmania (CCT)
Genetic Approaches to Osteoarthritis of the Hand; National Health & Medical Research Council (NHMRC)
Identification of susceptibility genes for familial haematological malignancies; Leukaemia Foundation (LF)
Identification of susceptibility genes for haematological malignancies; David Collins Leukaemia Foundation (DCLF)
Identifying genes in the HLA complex that influence clinical course and susceptibility in multiple sclerosis; National Health & Medical Research Council (NHMRC)
Identifying Genes that Influence Clinical Course and Susceptibility in Multiple Sclerosis; Australian Research Council (ARC)
Identifying inherited factors underlying familial haematological malignancies; David Collins Leukaemia Foundation (DCLF)
Interrogation of two novel genetic susceptibility loci for multiple sclerosis; National Health & Medical Research Council (NHMRC)
Investigating the genetics of familial haematological cancers in Tasmania; David Collins Leukaemia Foundation (DCLF)
Investigating the genetics of familial haematological cancers in Tasmania; David Collins Leukaemia Foundation (DCLF)
Investigating the genetics of familial haematological cancers in Tasmania; Cancer Council of Tasmania (CCT)
ITGA2: characterisation as a potential biomarker in prostate cancer; Cancer Council of Tasmania (CCT)
Prostate Cancer: Sun Exposure And Candidate Genes Modifying Risk; Commonwealth Department of Veterans Affairs (DVA)
Tasmanian familial haematological malignancy research study; Pfizer (PFIZER)
The ACRF Tasmanian Inherited Cancer Centre (ATICC); Australian Cancer Research Foundation (ACRF)
The MSR1 Gene and Risk of Prostate Cancer in the Tasmanian Population; Royal Hobart Hospital Research Foundation (RHHRF)
Transcriptome analysis for predicting response to radiotherapy in prostate cancer patients; Royal Hobart Hospital Research Foundation (RHHRF)
Corumbene Rural Primary Health Project Evaluation
Collaborative GWAS of dementia, Alzheimer's disease and related MRI and cognitive phenotypes - the CHARGE consortium - replication study
Colorectal medicine and genetics: linkage studies in hyperplastic polyposis syndrome
The Genetic Basis of Familial Syncope

Research Candidate Supervision

Dissecting the Genetics Architecture of Multiple Sclerosis
Investigating the Genetics of Primary Open-Angle Glaucoma in Tasmania
The Genetics of Familial Prostate Cancer in Tasmania
The Influence of HLA_DRA15 on Multiple Sclerosis
Understanding Osteoarthritis Utilising Magnetic Resonance Imaging