Web Access Research Portal

Researcher: Canales, J (Professor Juan Canales)

Fields of Research

Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
Neurosciences
Mental Health
Rehabilitation and Therapy (excl. Physiotherapy)
Health, Clinical and Counselling Psychology

Research Objectives

Substance Abuse
Expanding Knowledge in Psychology and Cognitive Sciences
Mental Health
Nervous System and Disorders
Human Pharmaceutical Products

Career Best Publications

Research Publications

A partial trace amine-associated receptor 1 agonist exhibits properties consistent with a methamphetamine substitution treatment; Addiction biology
Activation of the trace amine-associated receptor 1 prevents relapse to cocaine seeking; Neuropsychopharmacology
Addiction; Adult Neurogenesis in the Hippocampus: Health, Psychopathology, and Brain Disease
Adult Neurogenesis in the Hippocampus: Health, Psychopathology and Brain Disease; Academic Press
Adult neurogenesis in the hippocampus: new panoramas on drug abuse; El Faro: La Voz de la Red
Atypical dopamine transporter inhibitors: candidates for the treatment of psychostimulant addiction; Emerging Targets for Drug Addiction Treatment
Chronic unilateral stimulation of the nucleus accumbens at high or low frequencies attenuates relapse to cocaine seeking in an animal model; Brain stimulation
Deficient plasticity in the hippocampus and the spiral of addiction: focus on adult neurogenesis; Neurogenesis and Neural Plasticity
Exposure to N-Ethyl-N-Nitrosourea in adult mice alters structural and functional integrity of neurogenic sites; PloS one
Interaction between the trace amine-associated receptor 1 and the dopamine D2 receptor controls cocaine’s neurochemical actions; Scientific Reports
Long-term cognitive, emotional and neurogenic alterations induced by alcohol and methamphetamine exposure in adolescent rats; Progress in neuro-psychopharmacology & biological psychiatry
Modulation of methamphetamine's locomotor stimulation and self-administration by JHW 007, an atypical dopamine reuptake blocker; European Journal of Pharmacology
Monoamine transporters: vulnerable and vital doorkeepers; Progress in molecular biology and translational science
Neurogènesi en el cervell adult i salut mental; Psicologia positiva: Millora de la qualitat de vida per mitjà de la psicología
Prenatal exposure to alcohol and 3,4-methylenedioxymethamphetamine (ecstasy) alters adult hippocampal neurogenesis and causes enduring memory deficits; Developmental Neuroscience
Replacement treatment during extinction training with the atypical dopamine uptake inhibitor, JHW-007, reduces relapse to methamphetamine seeking; Neuroscience Letters
Selective activation of the trace amine-associated receptor 1 decreases cocaine's reinforcing efficacy and prevents cocaine-induced changes in brain reward thresholds; Progress in Neuro-Psychopharmacology and Biological Psychiatry
Substituting a long-acting dopamine uptake inhibitor for cocaine prevents relapse to cocaine seeking; Addiction biology
Targeting trace amine-associated receptors in the treatment of drug addiction; Emerging Targets for Drug Addiction Treatment
The atypical dopamine transport inhibitor, JHW 007, prevents amphetamine-induced sensitization and synaptic reorganization within the nucleus accumbens; Progress in neuro-psychopharmacology & biological psychiatry
The trace amine-associated receptor 1 modulates methamphetamine's neurochemical and behavioral effects; Frontiers in neuroscience
The Trace of Non-classical Biogenic Amines: A New Road to Addiction Recovery; Journal of Addiction Research & Therapy
Therapeutic-like properties of a dopamine uptake inhibitor in animal models of amphetamine addiction; International Journal of Neuro-Psychopharmacology
Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics; Biological psychiatry
Trace Amines and the Trace Amine-Associated Receptor 1: Pharmacology, Neurochemistry, and Clinical Implications; Frontiers in neuroscience

Research Projects

Investigation of the trace amine-associated receptor 1 as a target for pharmacotherapy in addictive disorders

Research Candidate Supervision