Web Access Research Portal

Researcher: Connelly, WM (Dr William Connelly)

Fields of Research

Cellular nervous system
Central nervous system
Sensory systems
Neurology and neuromuscular diseases
Vision science
Basic pharmacology
Cell physiology
Innate immunity

Research Objectives

Clinical health
Expanding knowledge in the biological sciences
Expanding knowledge in the biomedical and clinical sciences
Treatment of human diseases and conditions
Other health
Expanding knowledge in the health sciences

Career Best Publications

Research Publications

γ-hydroxybutyric acid (GHB) is not an agonist of extrasynaptic GABAA receptors; PLoS One
Cyfip1 haploinsufficiency does not alter GABAA receptor δ-subunit expression and tonic inhibition in dentate gyrus PV+ interneurons and granule cells; eNeuro
A distinct class of slow (⁓0.2-2 Hz) intrinsically bursting layer 5 pyramidal neurons determines UP/DOWN state dynamics in the neocortex; Journal of Neuroscience
Autaptic connections and synaptic depression constrain and promote gamma oscillations; PloS One
Differential short-term plasticity at convergent inhibitory synapses to the substantia nigra pars reticulata; Journal of Neuroscience
Dual function of thalamic low-vigilance state oscillations: rhythm-regulation and plasticity; Nature reviews. Neuroscience
GABAB Receptors Regulate Extrasynaptic GABAA Receptors; Journal of Neuroscience
L-type calcium channel-dependent inhibitory plasticity in the thalamus; Journal of Neurophysiology
Letter to the Editor: Genetic rescue of absence seizures; CNS Neuroscience & Therapeutics
Local versus global dendritic integration; Neuron
Metabotropic regulation of extrasynaptic GABAA receptors; Frontiers in neural circuits
Passive Synaptic Normalization and Input Synchrony-Dependent Amplification of Cortical Feedback in Thalamocortical Neuron Dendrites; Journal of Neuroscience
RPG: A low-cost, open-source, high-performance solution for displaying visual stimuli; Journal of Neuroscience Methods
Stable encoding of visual cues in the mouse retrosplenial cortex; Cerebral Cortex
The global spike: conserved dendritic properties enable unique Ca2+ spike generation in low-threshold spiking neurons; Journal of Neuroscience
The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS; British Journal of Pharmacology
The Thalamus as a Low Pass Filter: Filtering at the Cellular Level does Not Equate with Filtering at the Network Level; Frontiers in neural circuits
Variable action potential backpropagation during tonic firing and low-threshold spike bursts in thalamocortical but not thalamic reticular nucleus neurons; Journal of Neuroscience

Research Projects

Identifying the missing link between myelin loss and neurodegeneration [UNDER EMBARGO]; Multiple Sclerosis Australia (MSA)

Research Candidate Supervision