Web Access Research Portal

Researcher: Warr, C (Professor Coral Warr)

Fields of Research

Developmental genetics (incl. sex determination)
Cell metabolism
Signal transduction
Systems physiology
Cellular nervous system
Other biological sciences
Genetic immunology
Structural biology (incl. macromolecular modelling)
Receptors and membrane biology
Cell development, proliferation and death
Animal physiology - systems
Animal physiological ecology
Molecular evolution

Research Objectives

Expanding knowledge in the biological sciences
Clinical health
Health related to ageing
Expanding knowledge in the health sciences
Diagnosis of human diseases and conditions
Treatment of human diseases and conditions
Control of pests, diseases and exotic species in terrestrial environments
Sheep for wool
Sheep for meat

Career Best Publications

Research Publications

Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins; Insect Biochemistry and Molecular Biology
A new role for neuropeptide F signaling in controlling developmental timing and body size in Drosophila melanogaster; Genetics
A novel family of divergent seven-transmembrane proteins: Candidate odorant receptors in Drosophila; Neuron
A role for the Drosophila zinc transporter Zip88E in protecting against dietary zinc toxicity; PLoS ONE
A screen for genes expressed in the olfactory organs of Drosophila melanogaster identifies genes involved in olfactory behaviour; PLoS One
Candidate taste receptors in Drosophila; Science
Capturing embryonic development from metamorphosis: How did the terminal patterning signalling pathway of Drosophila evolve?; Current Opinion in Insect Science
Chemical communication in insects: The peripheral odour coding system of drosophila melanogaster; Sensing in Nature
Coexpression of two functional odor receptors in one neuron; Neuron
Copper overload and deficiency both adversely affect the central nervous system of Drosophila; Metallomics
Detection of volatile indicators of illicit substances by the olfactory receptors of Drosophila melanogaster; Chemical Senses
Development of the cellular immune system of Drosophila requires the membrane attack complex/perforin-like protein Torso-like; Genetics
Differential regulation of protein tyrosine kinase signalling by Dock and the PTP61F variants; FEBS Journal
Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling; Biochemical Journal
Drosophila olfactory receptors as classifiers for volatiles from disparate real world applications; Bioinspiration and Biomimetics
Functional analysis of a Drosophila melanogaster olfactory receptor expressed in Sf9 cells; Journal of Neuroscience Methods
Functional and molecular evolution of olfactory neurons and receptors for aliphatic esters across the Drosophila genus; Journal of Comparative Physiology A
Genome-wide screen for new components of the Drosophila melanogaster Torso receptor tyrosine kinase pathway; G3: Genes, Genomes, Genetics
High resolution structure of cleaved Serpin 42 da from Drosophila melanogaster; BMC Structural Biology
Identification and characterization of two distinct calmodulin-binding sites in the Trpl ion-channel protein of Drosophila melanogaster; Biochemical Journal
Identification of novel multi-transmembrane proteins from genomic databases using quasi-periodic structural properties; Bioinformatics
In vivo zinc toxicity phenotypes provide a sensitized background that suggests zinc transport activities for most of the Drosophila Zip and ZnT genes; Journal of Biological Inorganic Chemistry
Insulin-like signalling influences the coordination of larval hemocyte number with body size in Drosophila melanogaster; G3: Genes, Genomes, Genetics
MACPF/CDC proteins in development: insights from Drosophila torso-like; Seminars in Cell and Developmental Biology
Maternal Torso-Like coordinates tissue folding during drosophila gastrulation; Genetics
Molecular and cellular organization of insect chemosensory neurons; BioEssays
Molecular and functional evolution at the odorant receptor Or22 locus in Drosophila melanogaster; Molecular Biology and Evolution
Molecular basis of female-specific odorant responses in Bombyx mori; Insect Biochemistry and Molecular Biology
Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster; Proceedings of the National Academy of Sciences of the United States of America
Olfaction in Drosophila: Coding, genetics and e-genetics; Chemical Senses
Reduced glutathione biosynthesis in Drosophila melanogaster causes neuronal defects linked to copper deficiency; Journal of Neurochemistry
Systematic functional characterization of putative zinc transport genes and identification of zinc toxicosis phenotypes in Drosophila melanogaster; Journal of Experimental Biology
The torso-like gene functions to maintain the structure of the vitelline membrane in Nasonia vitripennis, implying its co-option into Drosophila axis formation; Biology open
The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function; PLoS Genetics
The Nucleus- and Endoplasmic Reticulum-Targeted Forms of Protein Tyrosine Phosphatase 61F Regulate Drosophila Growth, Life Span, and Fecundity; Molecular and Cellular Biology
The toll and Imd pathways are not required for wolbachia-mediated dengue virus interference; Journal of Virology
Torso-like functions independently of Torso to regulate Drosophila growth and developmental timing; Proceedings of the National Academy of Sciences of the United States of America
Torso-like is a component of the hemolymph and regulates the insulin signaling pathway in drosophila; Genetics
Torso-like mediates extracellular accumulation of Furin-cleaved Trunk to pattern the Drosophila embryo termini; Nature Communications
Trunk cleavage is essential for Drosophila terminal patterning and can occur independently of Torso-like; Nature Communications
Two uptake hydrogenases differentially interact with the aerobic respiratory chain during mycobacterial growth and persistence; Journal of Biological Chemistry
Using mouse and Drosophila models to investigate the mechanistic links between diet, obesity, type II diabetes, and cancer; International Journal of Molecular Sciences
Vacuolar-type H+-ATPase subunits and the neurogenic protein big brain are required for optimal copper and zinc uptake; Metallomics

Research Projects

A novel regulator of growth signalling in Drosophila; Australian Research Council (ARC)
Deciphering the role of SIK3 in development and disease; National Health & Medical Research Council (NHMRC)
Function and evolution of insect odorant receptors; Australian Research Council (ARC)
College of Experts 2020-2022: Prof Coral Warr

Research Candidate Supervision