Web Access Research Portal

Researcher: McLean, SR (Professor Stuart McLean)

Fields of Research

Health services and systems
Clinical pharmacology and therapeutics
Terrestrial ecology
Basic pharmacology
Zoology
Veterinary pharmacology
Toxicology (incl. clinical toxicology)
Pharmacology and pharmaceutical sciences
Pharmaceutical sciences
Analytical spectrometry
Clinical pharmacy and pharmacy practice
Criminology
Health psychology
Behavioural ecology
Biosecurity science and invasive species ecology
Behavioural neuroscience
Conservation and biodiversity
Instrumental methods (excl. immunological and bioassay methods)
Ecology
Ecological physiology
Analytical biochemistry
Animal physiology - systems
Medical biochemistry and metabolomics
Health and community services
Metabolic medicine
Animal physiological ecology
Obstetrics and gynaecology
Occupational and workplace health and safety
Other biological sciences
Applied statistics
Evolutionary biology
Anaesthesiology
Separation science
Primary health care
Horticultural crop growth and development
Biochemistry and cell biology
Epidemiology
Wildlife and habitat management
Igneous and metamorphic petrology
Sedimentology
Resource geoscience
Comparative physiology
Commercial law
Horticultural production
Forest health and pathology
Applied and developmental psychology
Motor control
Psychological methodology, design and analysis
Central nervous system
Other environmental sciences

Research Objectives

Public health (excl. specific population health)
Terrestrial biodiversity
Other health
Expanding knowledge in the environmental sciences
Other environmental management
Expanding knowledge in the health sciences
Control of pests, diseases and exotic species in terrestrial environments
Allied health therapies (excl. mental health services)
Veterinary pharmaceutical products
Marine biodiversity
Evaluation of health and support services
Expanding knowledge in the chemical sciences
Expanding knowledge in the biological sciences
Assessment and management of terrestrial ecosystems
Clinical health
Other plant production and plant primary products
Assessment and management of freshwater ecosystems
Occupational health
Other education and training
Neonatal and child health
Expanding knowledge in the agricultural, food and veterinary sciences
Mental health services
Treatment of human diseases and conditions
Health status (incl. wellbeing)
Evaluation, allocation, and impacts of land use
Nursing
Expanding knowledge in psychology
Horticultural crops
Hardwood plantations
Environmentally sustainable plant production
Other mineral resources (excl. energy resources)
Native forests
Evaluation of health outcomes

Career Best Publications

A nose for death: integrating trophic and informational networks for conservation and management; Frontiers in Ecology and Evolution
Development of tolerance to the dietary plant secondary metabolite 1,8-cineole by the Brushtail Possum (Trichosurus vulpecula); Journal of Chemical Ecology
Effect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets; Harm Reduction Journal
Filtration of crushed tablet suspensions has potential to reduce infection incidence in people who inject drugs; Drug and Alcohol Review
Injection of pharmaceuticals designed for oral use: harms experienced and effective harm reduction through filtration; Current Topics in Behavioral Neurosciences
Jensenone: Biological reactivity of a marsupial antifeedant from Eucalyptus; Journal of Chemical Ecology
Lipids of the tail gland, body and muzzle fur of the red fox, Vulpes Vulpes; Lipids
Pharmacokinetics of 1,8-cineole, a dietary toxin, in the brushtail possum (Trichosurus vulpecula): significance for feeding; Xenobiotica
Rapid absorption of dietary 1,8-cineole results in critical blood concentration of cineole and immediate cessation of eating in the common brushtail possum (Trichosurus vulpecula); Journal of Chemical Ecology
Scent chemicals of the Brushtail possum, Trichosurus vulpecula; Journal of Chemical Ecology
Scent Chemicals of the Tail Gland of the Red Fox, Vulpes vulpes; Chemical Senses
The influence of plant secondary metabolites on the nutritional ecology of herbivorous terrestrial vertebrates; Annual Review of Ecology Evolution and Systematics
Triacylglycerol estolides, a new class of mammalian lipids, in the paracloacal gland of the brushtail possum (Trichosurus vulpecula); Lipids
Volatile scent chemicals in the urine of the red fox, Vulpes vulpes; PLoS ONE

Research Publications

In vitro metabolism of Eucalyptus terpenes in the common ringtail possum, Trichorsurus vulpecula; ASCEPT
A Comprehensive, Broad Drug Screen in Whole Blood; 1997 Conference - The Impact of Pharmaceutical Research on Drug Development and the Improvement in Health Care
A model which predicts maintenance warfarin dosage requirements from the response to a single dose; British Journal of Clinical Pharmacology
A nose for death: integrating trophic and informational networks for conservation and management; Frontiers in Ecology and Evolution
A randomised trial of strategies to improve patient compliance with anticonvulsant therapy; Epilepsia
A trek through cyberspace; American Journal of Pharmaceutical Education
Amphotericin:fat or fiction?; SHPA Federal Biennial Clinical Pharmacy Conference: Clinical Controversies
Antagonism of some cyclohexamine-based drug combinations used for chemical restraint of southern elephant seals (Mirounga leonina); Australian Veterinary Journal
Application of solid-phase microextraction to the quantitative analysis of 1,8-cineole in blood and expired air in a Eucalyptus herbivore, the brushtail possum (Trichosurus vulpecula); Journal of Chromatography B
Audit of a monitoring service for free phenytoin; British Journal of Clinical Pharmacology
Automated screening procedure using gas chromatography-mass spectrometry for identification of drugs after their extraction from biological samples; Journal of Chromatography B: Biomedical Sciences and Applications
Baclofen does plasma level monitoring have a clinical role; Journal of Pharmacy Practice and Research
Behavioural responses of a generalist mammalian folivore to the physiological constraints of a chemically defended diet; Journal of Chemical Ecology
Biological monitoring of low level occupational xylene exposure and the role of recent exposure; Annals of Occupational Hygiene
Biologically meaningful scents: a framework for understanding predator–prey research across disciplines; Biological Reviews
Biotransformation of 1,8-cineole in the brushtail possum (Trichosurus vulpecula); Xenobiotica
Chemical restraint of Southern Elephant Seals Mirounga leonina: Use of medetomidine, ketamine and atipamezole and comparison with other cyclohexamine-based combinations; British Veterinary Journal
Comparative metabolism of 1,8-cineole after chronic ingestion in the brushtail possum (Trichosurus vulpecula) and koala (Phascolarctus cinereus); ACEPT
Comparative metabolism of dietary terpene, p-cymene, in generalist and specialist folivorous marsupials; Journal of Chemical Ecology
Compliance and clinical response in hypertension: a pilot study; Medical Journal of Australia
Conflicting demands on detoxification pathways influence how common brushtail possums choose their diets; Ecology
Consequences of biotransformation of plant secondary metabolites on acid-base metabolism in mammals - a final common pathway?; Journal of Chemical Ecology
Constraint of feeding by chronic ingestion of 1,8-cineole in the brushtail possum (Trichosurus vulpecula); Journal of Chemical Ecology
Determinants of patient compliance and clinical response in general-practice treatment of hypertension; Medical Journal of Australia
Determinants of Patient Compliance with Anticonvulsant Therapy; Epilepsia
Determinants of patient compliance, control, presence of complications, and handicap in non-insulin-dependent diabetes; Australian and New Zealand journal of medicine
Development of tolerance to the dietary plant secondary metabolite 1,8-cineole by the Brushtail Possum (Trichosurus vulpecula); Journal of Chemical Ecology
Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula; Journal of Chemical Ecology
Drugs, alcohol and road accidents in Tasmania; Medical Journal of Australia
Effect of cardiopulmonary bypass on the plasma concentrations of fentanyl and alcuronium; Journal of Clinical Pharmacy and Therapeutics
Effect of cytochrome P450 inhibitors on in vitro metabolism of 1,8-cineole in the common brushtail possum (Trichosurus vulpecula); Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting
Effect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets; Harm Reduction Journal
Effects of Filtration on the Presence of Particulate and Buprenorphine Content of Injections Prepared from Crushed Subutex® Tablets; APSAD 2011 Conference
Effects of Filtration on the Presence of Particulate and Oxycodone Content of Injections Prepared from Crushed OxyContin® Tablets; Current Drug Safety
Effects of two plant secondary metabolites, cineole and gallic acid, on nightly feeding patterns of the Common Brushtail Possum; Journal of Chemical Ecology
Fate of p-cymene in the koala; Conjoint Meeting of ASCEPT and APSA 1998
Fate of the dietary terpene, p-cymene, in the male koala; Journal of Chemical Ecology
Fate of the plant antifeedant salicin in the common brushtail possum Trichosurus vulpecula; Conjoint Meeting of ASCEPT and APSA 1998
Field immobilisation of southern elephant seals with intravenous tiletamine and zolazepam; Veterinary Record
Filtering pharmaceutical opioids for injection: What methods are being used and how effective are they?; APSAD Conference 2008
Filtration of crushed tablet suspensions has potential to reduce infection incidence in people who inject drugs; Drug and Alcohol Review
Food does not affect the bioavailability of baclofen; The Medical journal of Australia
Formation of reactive metabolites of phenacetin in humans and rats; Xenobiotica
Fox scents are so potent they can force a building evacuation. Understanding them may save our wildlife
Fox scents are so potent they can force a building evacuation. Understanding them may save our wildlife
Fox scents are so potent they can force a building evacuation: Understanding them may save our wildlife
Glucuronuria in the Koala; Journal of Chemical Ecology
Glycosuria in the koala; Annual Scientific Meeting of ASCEPT
Improving compliance with drug therapy; AJP: The Australian Journal of Pharmacy
Induction of xenobiotic metabolising enzymes in the common brushtail possum Trichosurus vulpecula, by eucalyptus terpenes; Conjoint Meeting of ASCEPT and APSA 1998
Induction of xenobiotic metabolising enzymes in the common brushtail possum, Trichosurus vulpecula, by Eucalyptus terpenes; Comparative Biochemistry and Physiology. Part C: Pharmacology, Toxicology & Endocrinology
Inhibition of the microsomal metabolism of 1,8-cineole in the common brushtail possum (Trichosurus vulpecula) by terpenes and other chemicals; Xenobiotica
Injecting MS Contin: What is the harm reduction evidence?; APSAD 2009 Conference
Injecting OxyContin: What is the harm reduction eveidence?; ATDC 2010: Reducing harm across the lifespan
Injection of pharmaceuticals designed for oral use: harms experienced and effective harm reduction through filtration; Current Topics in Behavioral Neurosciences
Integrating health behaviour theory and occupational health and safety issues in the workplace: Attitudes and beliefs towards health and safety; 34th Annual Conference of the Australian Psychological Society
Introduction to Pharmacology, 3rd Edition
Investigation of urinary levels of salbutamol in asthmatic patients receiving inhaled therapy; Journal of Clinical Pharmacy and Therapeutics
Jensenone: Biological reactivity of a marsupial antifeedant from Eucalyptus; Journal of Chemical Ecology
Lipids of the tail gland, body and muzzle fur of the red fox, Vulpes Vulpes; Lipids
Mass spectrometric determination of n-hydroxyphenacetin in urine using multiple metastable peak monitoring following thin-layer chromatography; Journal of Chromatography B: Biomedical Sciences and Applications
Mass Spectrometry in the characterization of metabolic pathways of terpenes in herbivorous marsupials; ANZSMS18
Mechanisms for Eliminating Monoterpenes of Sagebrush by Specialist and Generalist Rabbits; Journal of Chemical Ecology
Metabolic fate of dietary terpenes from Eucalyptus radiata in common ringtail possum (Pseudocheirus peregrinus); Journal of Chemical Ecology
Metabolism of Eucalyptus terpenes by herbivorous marsupials; Drug Metabolism Reviews
Metabolites of dietary 1,8-cineole in the male koala (Phascolarctos cinereus); Comparative Biochemistry and Physiology Part C
Microsomal metabolism and enzyme kinetics of the terpene p-cymene in the common brushtail possum (Trichosurus vulpecula), koala (Phascolarctos cinereus) and rat; Xenobiotica
Microsomal metabolism of the terpene 1,8-cineole in the common brushtail possum (Trichosurus vulpecula), koala (Phascolarctos cinereus), rat and human; Xenobiotica
Monitoring free plasma concentrations of phenytoin; British Journal of Clinical Pharmacology
Monitoring plasma levels of fluphenazine during chronic therapy with fluphenazine decanoate; Journal of Clinical Pharmacy and Therapeutics
N-hydroxyphenacetin, a new urinary metabolite of phenacetin in the rat; Drug Metabolism and Disposition
One for the road: on the utility of citation data for identifying problem hotels; Drug and Alcohol Review
Outliers and outsiders in skewed-up distribution; Australasian Epidemiology
Oxycodone as a component of multimodal analgesia for lactating mothers after Caesarean section: relationship between maternal plasma, breast milk and neonatal plasma levels; Australian and New Zealand Journal of Obstetrics and Gynaecology
Papyriferic Acid, an antifeedant triterpene from birch trees, inhibits succinate dehydrogenase from liver mitochondria; Journal of Chemical Ecology
Part 2(11): Specific Substances: Alcohol; Management of Alcohol and Drug Problems
Part 2(12): Specific Substances: Hallucinogens; Management of Alcohol and Drug Problems
Part 2(6) Specific Substances: Opioids; Management of Alcohol and Drug Problems
Part 2(7): Specific Substances: Tobacco; Management of Alcohol and Drug Problems
Part 2(8): Specific Substances: Central Nervous System Stimulants; Management of Alcohol and Drug Problems
Part 2(9): Specific Substances: Cannabis; Management of Alcohol and Drug Problems
Part2(10): Specific substances: Sedatives - Hypnotics; Management of Alcohol and Drug Problems
Pharmacokinetics of 1,8-cineole, a dietary toxin, in the brushtail possum (Trichosurus vulpecula): significance for feeding; Xenobiotica
Pharmacokinetics of intravenously administered ketamine in southern elephant seals (Mirounga leonina); Comparative Biochemistry and Physiology
Pharmacological prospectives on the detoxification of plant secondary metabolites: Implications for ingestive behaviour in herbivores; Journal of Chemical Ecology
Plasma concentrations of fentanyl with subcutaneous infusion in palliative care patients; British Journal of Clinical Pharmacology
Plasma protein binding of phenytoin in 100 epileptic patients; British Journal of Clinical Pharmacology
Quantitative urinary excretion of unmetabolised N tau-[Me-C-14]methylhistidine by the common ringtail possum (Pseudocheirus peregrinus) Marsupialia; Comparative Biochemistry and Physiology. A: Physiology
Rapid absorption of dietary 1,8-cineole results in critical blood concentration of cineole and immediate cessation of eating in the common brushtail possum (Trichosurus vulpecula); Journal of Chemical Ecology
Reducing harm from pharmaceutical opioid injection: The importance and effectiveness of filters; APSAD 2010 Conference
Scent chemicals of the Brushtail possum, Trichosurus vulpecula; Journal of Chemical Ecology
Scent Chemicals of the Tail Gland of the Red Fox, Vulpes vulpes; Chemical Senses
Scent glands of the common brushtail possum (Trichosurus vulpecula); New Zealand Journal of Zoology
Spatial scale of the patchiness of plant poisons: A critical influence on foraging efficiency; Ecology
Stability of cabergoline in fox baits in laboratory and field conditions; Wildlife Research
Tasmanian Drug Trends 1999. Findings from the Illicit Drug Reporting System (IDRS); 1999 National Drug Trends Conference
Tasmanian Drug Trends 1999. Findings from the Illicit Drug Reporting System (IDRS)
Tasmanian Drug Trends 2000. Findings from the Illicit Drug Reporting System (IDRS)
Tasmanian Drug Trends 2000. Findings from the Illicit Drug Reporting System (IDRS); 2000 National Drug Trends Conference
Tasmanian Drug Trends 2001. Findings from the Illicit Drug Reporting System (IDRS); 2001 National Drug Trends Conference
Tasmanian Drug Trends 2001. Findings from the Illicit Drug Reporting System (IDRS)
Tasmanian Drug Trends 2002. Findings from the Illicit Drug Reporting System (IDRS); 2002 National Drug Trends Conference
Tasmanian Drug Trends 2002. Findings from the Illicit Drug Reporting System (IDRS)
Tasmanian Drug Trends 2003. Findings from the Illicit Drug Reporting System (IDRS); 2003 National Drug Trends Conference
Tasmanian Drug Trends 2003. Findings from the Illicit Drug Reporting System (IDRS)
Tasmanian Party Drug Trends 2003. Findings from the Party Drugs Initiative (PDI)
Tasmanian Party Drug Trends 2003. Findings from the Party Drugs Initiative (PDI); 2003 National Drug Trends Conference
The determination of copper, zinc, cadium and lead in urine by high resolution ICP-MS; European Winter Conference on Plasma Spectrochemistry
The determination of copper, zinc, cadmium and lead in urine by high resolution ICP-MS; Journal of Analytical Atomic Spectrometry
The influence of plant secondary metabolites on the nutritional ecology of herbivorous terrestrial vertebrates; Annual Review of Ecology Evolution and Systematics
The integration of pharmacological and nonpharmacological treatments in drug/alcohol addictions
Towards outsmarting the wily fox: the chemistry of odours; Chemistry in Australia
Trends in hotel patronage and drink driving in Hobart, Tasmania; Drug and Alcohol Review
Triacylglycerol estolides, a new class of mammalian lipids, in the paracloacal gland of the brushtail possum (Trichosurus vulpecula); Lipids
Use of the respiratory stimulant doxapram in southern elephant seals (Mirounga leonina); The Veterinary Record
Volatile scent chemicals in the urine of the red fox, Vulpes vulpes; PLoS ONE
Warfarin dosage requirements: prospective clinical trial of a method for prediction from the response to a single dose; British Journal of Clinical Pharmacology

Research Projects

A Longitudinal Study of Psychological and Neuromotor Effects of Low Level Manganese Exposure; Australian Research Council (ARC)
Benzodiazepine and Pharmaceutical Opiate Misuse and Their Relationship to Crime; Turning Point Alcohol & Drug Centre (TPADC)
Detoxification of Eucalyptus Terpenes by Arboreal Marsupials; Australian Koala Foundation (AKLF)
Drug involvement in road accidents; Transport Tasmania (TT)
Drugs and road accidents; Australian Research Council (ARC)
Health and Safety in the Zinc Industry.; University of Tasmania (UTAS)
How do Marsupials which eat Eucalyptus leaf avoid Terpene Toxicity?; Australian Research Council (ARC)
IDRS Survey; Department of Health and Ageing (DHA)
Illicit Drug Reporting System (IDRS) Project No 2; Department of Health and Human Services Tasmania (DHHS)
Illicit Drugs Reporting System - Party Drugs Initiative (IDRS-PDI); Department of Health and Ageing (DHA)
Interactions between a Native Mammalian Herbivore and a Eucalypt Plantation Species; Holsworth Wildlife Research Endowment (HWRE)
Interactions between a Native Mammalian Herbivore and a Eucalypt Plantation Species; Holsworth Wildlife Research Endowment (HWRE)
Promotion of responsible drinking in licensed premises; Department of Health and Ageing (DHA)
Purchase of a Benchtop Triple Quadrupole Gas Chromatograph Mass Spectrometer; Australian Research Council (ARC)
Purchase of Inductively Coupled Plasma Optical Emission Spectrometer (ICP-OES); University of Tasmania (UTAS)
Research into Cabergoline Deployment Techniques for Fox Control; Phillip Island Nature Park (PINP)
The Pharmacokinetics of Plant Secondary Metabolites and their Effects on Feeding in the Brushtail Possum; Australian Research Council (ARC)
Evolution of resistance to cardiotoxic alkaloids in marsupials

Research Candidate Supervision

Adaptive metabolic strategies employed by eucalyptus eating marsupials
An automated semi-quantitative broad screen in whole blood
Anaesthesia of southern Elephant Seals
Aspects of the Pharmacotherapy of Airways disease
Clinical pharmacology
Comparison of the effects of morphine and tramadol on pain relief, balance, mobility, mood and incidence and type of adverse reactions when used for the treatment of chronic pain.
Effects of Plant Secondary Chemistry on Foraging Behaviour of Mammalian Herbivores
Pharmacogenetics and Chiral Aspects of Anti-Asthma Therapy
Pharmacokinetics of phenytoin in head injury and neurosurgical patients
The metabolic fate of dietary terpenes in folivorous marsupials
The Use of Oxycodene for Analgesia Post Caesarean Section- Maternal Plasma Levels, Breast Milk Levels and Neonatal Levels; Survey of Use in Australian and New Zealand Obstetric Units
Title- The Pharmacokinetics of Chiral Non-Steroidal Anti-Inflammatory Drugs in Synovial Fluid and Plasma
Toxicology