Web Access Research Portal

Researcher: Fairfax, KA (Dr Kirsten Fairfax)

Fields of Research

Cell development, proliferation and death
Bioinformatic methods development
Biochemistry and cell biology
Cellular immunology
Gene expression (incl. microarray and other genome-wide approaches)
Haematological tumours
Immunogenetics (incl. genetic immunology)

Research Objectives

Clinical health
Diagnosis of human diseases and conditions
Other health

Career Best Publications

Research Publications

A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics; Nature Immunology
Assessing immune-related adverse events of efficacious combination immunotherapies in preclinical models of cancer; Cancer Research
BAFF-driven autoimmunity requires CD19 expression; Journal of Autoimmunity
CD19 differentially regulates BCR signalling through the recruitment of PI3K; Autoimmunity
Deleting the BAFF receptor TACI protects against systemic lupus erythematosus without extensive reduction of B cell numbers; Journal of Autoimmunity
Fluorescent antibiotics, vomocytosis, vaccine candidates and the inflammasome; Clinical & Translational Immunology
Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion; Journal of Immunology
Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans; Nucleic Acids Research
Haemopedia: an expression atlas of murine hematopoietic cells; Stem Cell Reports
Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia; Cancer Cell
Identification of a Siglec-F+ granulocyte-macrophage progenitor; Journal of Leukocyte Biology
IL-10 regulates Aicda expression through miR-155; Journal of Leukocyte Biology
NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells; The Journal of Experimental Medicine
The RNA-binding protein HuR (Elavl1) is essential for the B cell antibody response; Nature Immunology
The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice; Science Signaling
Transcriptional profiling of eosinophil subsets in interleukin-5 transgenic mice; Journal of Leukocyte Biology

Research Projects

Functional interrogation of loci associated with the regulation of haematopoiesis; Maddie Riewoldt's Vision (MRV)

Research Candidate Supervision