Web Access Research Portal

Researcher: Melton, P (Dr Phillip Melton)

Fields of Research

Gene mapping
Epigenetics (incl. genome methylation and epigenomics)
Clinical pharmacology and therapeutics
Foetal development and medicine
Mental health services
Anthropological genetics
Gastroenterology and hepatology
Obstetrics and gynaecology
Cardiology (incl. cardiovascular diseases)
Biological adaptation
Cancer diagnosis
Cancer genetics
Molecular targets

Research Objectives

Clinical health
Preventive medicine
Neonatal and child health
Public health (excl. specific population health)
Expanding knowledge in the mathematical sciences
Expanding knowledge in psychology
Human pharmaceutical treatments
Prevention of human diseases and conditions
Mental health
Expanding knowledge in the biological sciences
Health status (incl. wellbeing)
Diagnosis of human diseases and conditions
Treatment of human diseases and conditions
Expanding knowledge in the biomedical and clinical sciences

Career Best Publications

Research Publications

Assessment of cognition and personality as potential endophenotypes in the Western Australian Family Study of Schizophrenia; Schizophrenia Bulletin
Bile acids associate with specific gut microbiota, low level alcohol consumption and liver fibrosis in patients with non-alcoholic fatty liver disease; Liver International
Butyrate generated by gut microbiota and its therapeutic role in metabolic syndrome; Pharmacological Research
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age; Genome Medicine
GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics; BMC Proceedings
Genetic influence on scar height and pliability after burn injury in individuals of European ancestry: A prospective cohort study; Burns
Genome-wide association study of autistic-like traits in a general population study of young adults; Frontiers in Human Neuroscience
Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study; Journal of Lipid Research
Identification of differentially methylated CpG sites in fibroblasts from keloid scars; Biomedicines
Longitudinal Data Analysis for Genetic Studies in the Whole-Genome Sequencing Era; Genetic Epidemiology
Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification; Clinical Epigenetics
Machine learning-based DNA methylation score for fetal exposure to maternal smoking: development and validation in samples collected from adolescents and adults; Environmental Health Perspectives
Maternal smoking during pregnancy induces persistent epigenetic changes into adolescence, independent of postnatal smoke exposure and is associated with cardiometabolic risk; Frontiers in Genetics
Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns; BMC Genomics
Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems; Epigenomics
Paternal genetic structure in contemporary Mennonite communities from the American midwest; Human Biology
rs641738C>T near MBOAT7 is associated with liver fat, ALT, and fibrosis in NAFLD: a meta-analysis; Journal of Hepatology
Statins do not directly inhibit the activity of major epigenetic modifying enzymes; Cancers

Research Projects

Epigenetic Biomarker Discovery for Cardiovascular Disease Risk Stratification of Women Following Preeclampsia; National Health & Medical Research Council (NHMRC)

Research Candidate Supervision