Web Access Research Portal

Researcher: Muller, HK (Professor Konrad Muller)

Fields of Research

Cellular Immunology
Respiratory Diseases
Tumour Immunology
Pathology
Oncology and Carcinogenesis
Immunology
Cancer Cell Biology
Autoimmunity
Clinical Sciences
Epidemiology
Medical Biochemistry: Nucleic Acids
Psychiatry (incl. Psychotherapy)
Central Nervous System
Medical and Health Sciences
Medical Biochemistry and Metabolomics
Cancer Genetics
Dermatology
Humoural Immunology and Immunochemistry
Cellular Nervous System
Medical Bacteriology
Veterinary Immunology
Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
Cardiology (incl. Cardiovascular Diseases)
Mental Health Nursing
Basic Pharmacology
Health and Community Services
Aboriginal and Torres Strait Islander Health
Haematology
Zoology
Neurosciences
Medical Microbiology
Cell Development, Proliferation and Death
Structural Biology (incl. Macromolecular Modelling)
Animal Physiology - Cell
Neurology and Neuromuscular Diseases
Peripheral Nervous System
Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)
Physiology
Genetics

Research Objectives

Health
Immune System and Allergy
Cancer and Related Disorders
Respiratory System and Diseases (incl. Asthma)
Skin and Related Disorders
Nervous System and Disorders
Expanding Knowledge in the Environmental Sciences
Forest and Woodlands Flora, Fauna and Biodiversity
Inherited Diseases (incl. Gene Therapy)
Environmental Health
Mental Health
Community Service (excl. Work)
Endocrine Organs and Diseases (excl. Diabetes)
Cardiovascular System and Diseases
Diabetes
Flora, Fauna and Biodiversity of environments
Digestive System Disorders
Infectious Diseases
Education and Training Systems
Skeletal System and Disorders (incl. Arthritis)
Human Pharmaceutical Products

Career Best Publications

Research Publications

$130,000 microscope gives new focus for cancer research
β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction; Scientific Reports
A 12 Year Study of Langerhans Cell Migration and Function: Lessons for the Prevention of Skin Cancers; MEPSA Conference
A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study; International Journal of COPD
A window on immunity in Antarctica; Eighth International Congress of Mucosal Immunology
Abrogation of afferent lymph dendritic cell function after cutaneously applied chemical carcinogens; Cellular Immunology
Abrogation of delayed type hypersensitivity response to Candida albicans produced by a molecular mimic of phosphorylated prolactin; Journal of Neuroimmunology
Acquisition of immune function during the development of the Langerhans cell network in neonatal mice; Immunology
After cutaneous DMBA treatment, newly arrived Langerhans cells induce antigen specific immunosuppression; 5th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology
Airway Angiogenesis And basement Membrane Remodeling In Smokers And Chronic Obstructive pulmonary Disease: cross-sectional And Longitudinal Studies
Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease; The International Journal of Chronic Obstructive Pulmonary Disease
Airway histone deacetylase-2 increases after smoking cessation, but is not affected by inhaled corticosteroids in Chronic Obstructive Pulmonary Disease (COPD): A randomized controlled trial; American Thoracic Society (ATS)
Alterations of Langerhans cell function during the early stages of cutaneous carcinogenesis confers immunosuppression rather than immunity; International Investigative Dermatology
Altered kinetics of antigen uptake by neonatal Langerhans cell: Implications for tolerance induction; Natural Products Which Modulate Tissue Repair
Analysis of dendritic cells during carcinogen induced immunosuppression; 9th International Congress of Immunology
Analysis of migrating epidermal dendritic cells in carcinogen and contact sensitiser induced immunosuppression; 28th Annual meeting of the Australasian Society for Immunology
Antarctic isolation: Immune and viral studies; Immunology and Cell Biology
Antarctic isolation: immunological changes in expeditioners; Annual Meeting of the Australian Society for Microbiology
Antigen induced maturation of neonatal Langerhans cells; 11th International Congress of Immunology
Antigen presentation by modified dendritic cells as a strategy to down regulate autoimmunity; 4th International Workshop on the Molecular and Cell Biology of Autoantibodies and Autoimmunity
Antigen specific suppression in cutaneous carcinogenesis; Joint Meeting of the Australian and New Zealand Environmental Mutagen Society and the Australasian Society for Experimental Pathology
Are Recent Cell Immigrants to Adult Skin the Functional Correlate of Neonatal Cells?; 6th International Symposium on Dendritic Cells
Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional study ; Respiratory Research
Basement membrane remodelling in COPD responds to inhaled corticosteroids; The Thoracic Society of Australia & New Zealand Annual Scientific Meeting
Book review ; Analytical morphology: Theory, applications and protocols; Pathology
Carcinogen induced Langerhans cells: the functional correlate of neonatal Langerhans cells?; 38th National Scientific Conference of the Australian Society for Medical Research
Carcinogen-modified dendritic cells induce immunosuppression by incomplete T-cell activation resulting from impaired antigen uptake and reduced CD86 expression; Immunology
Cell mediated immunity in Antarctic wintering personnel; 1984-1992; Immunology and Cell Biology
Cell-mediated immunity and HPA axis dysfunction in posttraumatic stress disorder; Medical Journal of Australia
Cell-mediated immunity in combat veterans with post-traumatic stress disorder; The Medical Journal of Australia
Chair - The scientific basis of medicine; Australian Society for Experimental Pathology
Changes in airway histone deacetylase2 in smokers and COPD with inhaled corticosteroids: A randomized controlled trial; PLoS One
Characterisation of carcinogen induced regulatory effector cells; 37th Annual Meeting of the Australian Society for Medical Research
Chemical carcinogens and antigens contribute to cutaneous tumor promotion by depleting epidermal Langerhans cells; Carcinogenesis
Chemical carcinogens and antigens induce immune suppression via Langerhans' cell depletion; Immunology
Comparing factor VIII with collagen IV for immuno-staining of vessels; The Thoracic Society of Australia & New Zealand Annual Scientific Meeting
Cutaneous tolerance -- A potential strategy for treatment of autoimmune disease; Federation of Immunological Societies of Asia-Oceania
DEC-205lo Langerinlo neonatal Langerhans' cells preferentially utilize a wortmannin-sensitive, fluid-phase pathway to internalize exogenous antigen; Immunology
Delayed immune response during neonatal development: A link between phenotype and function; 31st Annual Meeting of the Australasian Society for Immunology
Dendritic cells migrating from carcinogen-treated skin have reduced antigen-presenting function; Dendritic cells in fundamental and clinical immunology
Dietary vitamin D alters the response of the skin to UVB-irradiation depending on the genetic background of the mice; Photochemical & Photobiological Sciences
Dietary Vitamin D3 deficiency alters skin UVB-induced DNA damage in neonatal mice; The Third Australian Health and Medical Research Congress
Dietary vitamin D3 influences UVB induced DNA damage and immunosuppression; Mutagenesis and Experimental Pathology of Australasia Conference
Dietary vitamin D3 protects against UVB-induced immunosuppression in C57BL/6, but not BALB/c mice; MEPSA Conference
Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis; Pigment cell & melanoma research
Distinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same disease; Histopathology
Does combat-related post-traumatic stress disorder have a unique effect on immune responses; Australasian Flow Cytometry Group 18th Annual Meeting
Does combat-related post-traumatic stress disorder have a unique effect on immune responses?; Australasian Society for Immunology Annual Scientific Meeting
Down-regulation of an established immune response via chemical carcinogen or UVB-altered skin; Immunology and Cell Biology
Downregulation of an established immune response - a possible tactic for the treatment of autoimmune disease; Australasian Society for Immunology - Annual Conference
Downregulation of immune responses by modified dendritic cells; Australasian Society for Experimental Pathology
Dysregulation of apoptosis and p53 signalling pathway during photocarcinogenesis; 8th Congress of the European Society for Photobiology
Dysregulation of apoptosis during UVB skin carcinogenesis in mice; 90th Annual Meeting of the American Association for Cancer Research
Early stages of recovery following spinal cord injury in the neonatal opossum; Australian Neuroscience Society
Effect of UV Radiation on the Neonatal Skin Immune System - Implicaions for Melanoma; Photochemistry and Photobiology
Effect of UV Radiation on the Neonatal Skin Immune System- Implications for Melanoma
Effects of ultraviolet light on ovine cells; 4th International Workshop on Langerhans cells
Effects of UV on the migration and function of epidermal antigen presenting cells; Mutation Research
Effects of UVB light on sheep Langerhans cells; Sixth Congress of the European Society for Photobiology
Effects of UVB light on structure, migration and function of ovine epidermal dendritic cells; 5th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology
Enhanced growth of murine melanoma in ultraviolet-irradiated skin is associated with local inhibition of immune effector mechanisms; Journal of Immunology
Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease; Medical Oncology
Epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD) airways is attenuated by inhaled corticosteroids (ICS); British Thoracic Society
Epithelial mesenchymal transition (EMT) in large airways is attenuated by inhaled fluticasone propionate (FP) in COPD: a randomized controlled trial; The 8th International Young Investigators’ Meeting (YIM) on Airway Smooth Muscle and Fibroblast Biology
Epithelial mesenchymal transition (EMT) in patients with chronic obstructive disease (COPD); The Thoracic Society of Australia & New Zealand Annual Scientific Meeting
Epithelial mesenchymal transition (EMT) in small and large airways of smokers: potential role in both airway fibrosis and cancer; The 8th International Young Investigators’ Meeting (YIM) on Airway Smooth Muscle and Fibroblast Biology
Epithelial mesenchymal transition (EMT) in the small and large airways of lung cancer patients undergoing thoracotomy; European Respiratory Society Annual Congress
Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction; International Journal of Chronic Obstructive Pulmonary Disease
Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease; Respiratory Research
Examination of B7 molecule expression of migrating ovine Langerhans cells after UV treatment; Australasian Flow Cytometry Group 18th Annual Meeting
Expression of P-glycoprotein by Dendritic Cells is not Required for Function; 6th International Symposium on Dendritic Cells
Faculty of Oral Pathology; 43rd Annual Meeting of the Royal College of Pathologists of Australasia
Failure of carcinogen-altered dendritic cells to initiate T cell proliferation is associated with reduced IL-1 beta secretion; Cellular Immunology
Failure of carcinogen-altered dendritic cells to initiate T cell proliferation is associated with reduced IL-1B secretion; 9th International Congress of Immunology
Fluorescent probes lack specificity for functional P-glycoprotein detection; 38th National Scientific Conference of the Australian Society for Medical Research
Fluticasone propionate attenuates epithelial mesenchymal transition (EMT) in COPD; Respirology, 17 (Supp 1)
Graduates of the University of Tasmania Medical School:career achievements 10-23 years after graduation; Medical Journal of Australia
Immature Langerhans cells: Central role in tolerance induction in carcinogen-treated and neonatal skin; 7th International Workshop on Langerhans cells
Immune responses during an antarctic summer; Pathology
Impaired CD40-signalling in Langerhans' cells from murine neonatal draining lymph nodes: implications for neonatally induced cutaneous tolerance; Clinical and Experimental Immunology
Induction of melanoma in p53 knockout mice by UV irradiation; 26th Annual Meeting of the American Society for Photobiology
Induction of peripheral tolerance in neonatally thymectomized mice by immunization through chemical carcinogen-altered skin; Cellular Immunology
Induction of Primary Cutaneous melanomas in C3H Mice by Combined Treatment with Ultraviolet Radiation, ethanol and aloe emodin; MEPSA Conference
Induction of Primary Cutaneous Melanomas in C3H Mice by Combined Treatment with Ultraviolet Radiation, Ethanol and Aloe Emodin; Photochemistry and Photobiology
Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD; International Journal of COPD
Inhaled corticosteroids (ICS) attenuate epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD) - implications for lung cancer prophylaxis; Australian Lung Cancer Conference (ALCC)
Inhaled corticosteroids (ICS) attenuates epithelial mesenchymal transition (EMT) in COPD: a key to understanding long term benefits; European Respiratory Society Annual Congress
Inhaled corticosteroids in airway remodelling in COPD; Thorax
Inhaled corticosteroids is effective on only some aspects of bronchial vascular remodelling in COPD; Thoracic Society of Australia and New Zealand
Inhibition of Apoptosis via Loss of Fas-ligand in UV-induced Apoptosis and Skin Carcinogenesis; American Association for Cancer Research
Interleukin 12: A cytokine at the interface of inflammation and immunity; 37th National Scientific Conference of the Australian Society for Immunology
Investigation of immunologic pulmonary metastases in the presence of protective tumor immunity; 90th Annual Meeting of the American Association for Cancer Research
Is P-glycoprotein involved in Langerhans cell function?; 38th National Scientific Conference of the Australian Society for Medical Research
Jensenone: Biological reactivity of a marsupial antifeedant from Eucalyptus; Journal of Chemical Ecology
Lack of evidence from a transgenic mouse model that the activation and migration of melanocytes to the epidermis after neonatal UVR enhances melanoma development; The Journal of Investigative Dermatology
Langerhans cell depletion is a key component of cutaneous tumour promotion; Federation of Immunological Societies of Asia-Oceania
Langerhans cell function during carcinogen induced immunosuppression; Langerhans Cells, 4th International Workshop
Langerhans cell function during carcinogenesis; Australasian Society for Experimental Pathology
Langerhans cell function during the early stages of carcinogenesis; 5th International Workshop on Langerhans cells
Loss of Fas-Ligand Expression in Mouse Keratinocytes during UV Carcinogenesis; American Journal of Pathology
Maternal milk T cells drive development of transgenerational Th1 immunity in offspring thymus; Journal of Immunology
Maturation of antigen presenting cell function in neonatal Langerhans cells; 1st Annual Meeting of the Haematology Society of Australia and New Zealand
Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation; Oncogene
Melanocytes in conditional Rb-/- mice are normal in vivo but exhibit proliferation and pigmentation defects in vitro; Pigment Cell Research
Melanoma susceptibility as a complex trait: genetic variation controls all stages of tumor progression; Oncogene
Mice With Genetically Determined High Susceptibility to Ultraviolet (UV)-Induced Immunosuppression Show Enhanced UV Carcinogenesis; Investigative Dermatology
Migrating ovine Langerhans cells antigen presenting ability reduced after cutaneous exposure to ultraviolet light; Australasian Society for Immunology
Migration of Langerhans cells and ãä+ dendritic cells from UV-B-irradiated sheep skin; Immunology and Cell Biology
Modification of dendritic cell function -Implications for autoimmunity; 1st Annual Meeting of the Haematology Society of Australia and New Zealand
Modification of skin immune system function by dietary vitamin D3 is influenced by age and gender; The Third Australian Health and Medical Research Congress
Modifying skin immunity; 37th Annual Meeting of the Australian Society for Medical Research
Modulation of Langerhans cell function: A role for antigen dose; 38th National Scientific Conference of the Australian Society for Medical Research
Modulation of lymphocyte migration to the murine spleen after macrophage phagocytosis of blood-borne particulate material; Immunological Investigations: A Journal of Molecular and Cellular Immunology
Morphometric differences between thin basement membrane and minimal change nephropothies revealed by computerised analysis of light microscopical glomerular images; Joint scientific meeting of the Royal College of Pathologists of Australasia
Multidrug resistance and resistance to natural killer cells; 9th International Congress of Immunology
Multiple metastatic melanoma induced by neonatal ultraviolet radiation rtreatment of CDKR24C/R24C /TPRAS mice; 19th International Pigment cell conference
Murine melanomas accelerated by a single UVR exposure carry photoproduct footprints but lack UV signature C>T mutations in critical genes; Oncogene
Murine neonatal melanocytes exhibit a heightened proliferative response to ultraviolet radiation and migrate to the epidermal basal layer; Journal of Investigative Dermatology
Neonatal exposure to UVR alters skin immune system development, and suppresses immunity in adulthood; Immunology and Cell Biology
Neonatal Langerhans cells and maturation of antigen presenting cells; 6th International Workshop on Langerhans cells
Neonatal Langerhans cells are defective in uptake and presentation of antigen and induce immunosuppression; 37th Annual Meeting of the Australian Society for Medical Research
Neonatal Langerhans cells induce antigen specific suppression; 28th Annual meeting of the Australasian Society for Immunology
Neonatal Langerhans cells process, but do not effectively present, antigen resulting in impaired immunity; 9th International workshop on Langerhans cells
Neonatal Ultraviolet Radiation Exposure is Critical for Malignant Melanoma Induction in Pigmented Tpras Transgenic Mice; Journal of Investigative Dermatology
Neutrophil numbers are decreased in bronchial biopsies from patients with COPD; European Respiratory Society Annual Congress
Obituary, Roland Arnold Rodda - 1917-1993
Ozone Sun Cancer: Molecular and Cellular Mechanisms Prevention
P-glycoprotein mediated multidrug resistance and its implications for pathology; Pathology
p53 protects against skin cancer induction by UV-B irradiation; Oncogene
Parathyroid morphology and menin staining in Multiple Endocrine Neoplasia Type 1 (MEN 1); RCPA Pathology Update 2016
Patron of clinical immunology - Richard Nairn
Phenotype of migrating murine antigen presenting cells in cutaneous carcinogenesis; Australasian Society for Immunology Annual Scientific Meeting
Phenotypic analysis of migrating epidermal dendritic cells in carcinogen and contact sensitiser induced immunosuppression; 5th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology
Phenotypic analysis of migrating murine antigen presenting cells in a model of cutaneous carcinogenesis; Australasian Flow Cytometry Group 18th Annual Meeting
Plasticity of melanoma in vivo: murine lesions resulting from Trp53, but not Cdk4 or Arf deregulation, display neural transdifferentiation; Pigment Cell and Melanoma Research
Platelet activating factor receptor (PAFR) expression increases in airways of current smokers; Respirology, 17 (Supp 1)
Platelet-activating factor receptor (PAFr) is upregulated in small airways and alveoli of smokers and COPD patients; Respirology
Plenary - Mechanistic basis of the specific host response in sites of viral pathology; 43rd Annual Meeting of the Royal College of Pathologists of Australasia
Poverty of inflammation in neonatal skin; 7th World congress on inflammation
Presentation by antigen following topical DMBA treatment is mediated by newly arrived Langerhans cells; 28th Annual meeting of the Australasian Society for Immunology
President's Column
President's Column
President's Column
President's Column
Prevention of Autoimmunity by Induction of Cutaneous Tolerance; Cellular Immunology
Processing of complex antigens and simple hapten-like molecules by epidermal Langerhans cells; Leukocyte Biology
Professor Richy Nairn, 1919 to 1995
Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD; Respirology
Protection Against Autoimmune Disease by Immunisation Through Skin Containing Immature Langerhans Cells; 6th International Symposium on Dendritic Cells
Proteomics identifies enhanced expression of stefin A in neonatal murine skin compared with adults: functional implications; British Journal of Dermatology
Proteomics identifies enhanced expression of stefinA in neonatal murine skin compared to adult skin: Functional implications; 35th Annual Scientific Meeting of the Australasian Society for Immunology
Re-establishment of blood-spinal cord barrier to protein following injury; Australian Neuroscience Society
Recent immigrants to the skin present antigen following carcinogen treatment; 37th Annual Meeting of the Australian Society for Medical Research
Reduced dendritic cell function during the early stages of chemical carcinogenesis; 27th Annual Meeting of the Australasian Society for Immunology
Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease ; Respirology
Reticular basement membrane vessels are increased in COPD bronchial mucosa by both factor VIII and collagen IV immunostaining and are hyperpermeable; Journal of Allergy
Retinoic acid protests Langerhans' cells from the effects of the tumour promoter 12-O-tetradecanoylphorbol 13-acetate; Immunology
Richard Charles Nairn, Foundation Professor of Pathology and Immunology at Monash University; Pathology
Role of p53 and Fas-ligand in UV-induced Apoptosis and Skin Carcinogenesis; MEPSA Conference
Seasonal cutaneous immune responses in an Antarctic wintering group: No association with testosterone, vitamin D metabolite or anxiety score; Arctic Medical Research
Semiquantitative analysis for collagen IV, fibronectin and laminin B in thin basement membrane nephropathy by immunohistochemistry; Joint scientific meeting of the Royal College of Pathologists of Australasia
Session Chair; Natural Products Which Modulate Tissue Repair
Smoking cessation but not inhaled corticosteroids (ICS) can increase histone deacetylase 2 (HDAC2)] in COPD ; The European Respiratory Journal
Smoking has potential to initiate basement membrane disruption and epithelial mesenchymal transition in COPD ; European Respiratory Society Annual Congress
Smoking has potential to initiate epithelial mesenchymal transition (EMT) in the airway mucosa
Sun Exposure, Sunscreen and Their Effects on Epidermal Langerhans Cells; Photochemistry and Photobiology
Superficial spreading-like melanoma in Arf-/-::Tyr-NrasQ61K::K14-Kitl mice: Keratinocyte kit ligand expression sufficient to 'translocate' melanomas from dermis to epidermis; The Journal of Investigative Dermatology: An International Journal for Research in Cutaneous Biology
Systemic immunosuppression caused UV light; Australian Society for Experimental Pathology
The immune response in the aetiology of Schizophrenia: a review; Malaysian Journal of Psychiatry
The Immune Response of the Tasmanian Devil (Sarcophilus harrisii) and Devil Facial Tumour Disease; EcoHealth
The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL); Respiratory research
The role of mast cells in neonatally induced suppression; 35th Annual Scientific Meeting of the Australasian Society for Immunology
The skin immune system and immunosurveillance; Skin immune system (SIS)
The skin immune system and the challenge of tumour immunosurveillance
The skin immune system and tumor immunosurveillance; The Skin Immune System
The use of spectrophotometry to estimate melanin density in caucasians; 4th World Conference on Melanoma
The Use of Spectrophotometry to Estimate Melanin Density in Caucasions; Cancer Epidemiology, Biomarkers and Prevention
Tobacco smoke condensate cutaneous carcinogenesis: changes in Langerhans cells and tumor regression; International Journal of Experimental Pathology
Tobacco smoke induced lung granulomas and tumors: Association with pulmonary Langerhans cells; Pathology
Trans-Epithelial Immune Cell Transfer during Suckling Modulates Delayed-Type Hypersensitivity in Recipients as a Function of Gender; PLOS One
Transepidermal dendritic cell clearance in Mycobacterium ulcerans infection; World Association of Societies of Pathology/Royal College of Pathologists of Australasia Meeting
Transforming growth factor (TGF) β1 and Smad signalling pathways: A likely key to EMT-associated COPD pathogenesis; Respirology
Transforming growth factor - beta 1 (TGF-β 1) expression is related to reticular basement membrane (Rbm) hypervascularity in smokers and COPD; European Respiratory Society Annual Congress
Tumour immunology - Chair; Federation of Immunological Societies of Asia-Oceania
Tumour promoters but not initiators deplete Langerhans cells from murine epidermis; British Journal of Cancer Management
Ultraviolet light induced injury: Immunological and inflammatory effects
Ultraviolet radiation effects on the proteome of skin cells; Advances in Experimental Medicine and Biology: Radiation Proteomics
UV - induced changes in the skin: Can they be repaired?; Oxidative pathways in Health and Disease
UV irradiation augments lymphoid malignancies in mice with one functional copy of wild-type p53; Proceedings of the National Academy of Sciences of the United States of America
UV irradiation augments lymphoid malignancies in mice with only one copy of p53; 90th Annual Meeting of the American Association for Cancer Research
UV-B-induced immune suppression: implications for infection; The health consequences of ozone depletion
UV-induced changes in the skin: can they be repaired?; Redox Report
UVA, UVB and protection; Oxidative pathways in Health and Disease
UVB induced experimental carcinogenesis: Dysregulation of apoptosis and p53 signalling pathway; Oxidative pathways in Health and Disease
UVB irradiation prevents antigen uptake by epidermal dendritic cells; Joint Meeting of the Australian and New Zealand Environmental Mutagen
UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6clow MHCIIhi macrophages; Journal of Investigative Dermatology
Vascular and basement membrane remodelling in smokers and COPD; European Respiratory Journal
Vitamin D deficiency alters the contact sensitivity response in BALB/c mice; 35th Annual Scientific Meeting of the Australasian Society for Immunology
Vitamin D promotes neonatal tolerance induction to contact sensitisers; Australasian Society for Immunology Meeting
Vitamin D3 deficiency enhances contact hypersensitivity in male but not in female mice ; Cellular Immunology
Vitamin D3 influences skin draining lymph node dendritic cells in neonatal male mice; National Health and Medical Research Congress
Vitamin D3 nutrition influences regulatory T cell induction in neonatal tolerance and adult immunity; MEPSA Conference
Vitamin D3, the skin immune system and cutaneous carcinogenesis; UV Workshop, National Institute of Water and Atmospheric Research (NIWA)

Research Projects

A Pilot Study to Examine Biological, Lifestyle and Genetic Risk Factors Associated with the Development of Multiple Non-melanoma Skin Cancers; University of Tasmania (UTAS)
A Pilot Study to Examine Biological, Lifestyle and Genetic Risk Factors Associated with the Development of Second and Subsequent Non-melanoma Skin Cancers in People with a History of Skin Cancer; Cancer Council of Tasmania (CCT)
Analysis of antigen presenting cells and T cells during carcinogen induced immunosuppression.; National Health & Medical Research Council (NHMRC)
Analysis of Immunity in Antarctic Expedition Personnel; Antarctic Science Advisory Committee (ASAC)
Analysis of immunity in Antarctic expedition personnel; Antarctic Science Advisory Committee (ASAC)
Analysis of Langerhans cell function during chemically and physically induced carcinogenesis; Tasmanian Cancer Council (TCC)
Analysis of Langerhans cell function during chemically and physically induced carcinogenesis; Tasmanian Cancer Council & W P Holman Clinics (TCC/WPH)
Analysis of Reduced IFN-y and Increased IL-12 (p40) as a Mechanism Contributing to Carcinogen Induced Immunosuppression; Royal Hobart Hospital Research Foundation (RHHRF)
Antigen Handling Costimulatory Molecule Expression and Intracellular Signalling of IL-10 Induced Human Tolerogenic Dendritic Cells; Royal Hobart Hospital Research Foundation (RHHRF)
Biohazard Cabinet; National Health & Medical Research Council (NHMRC)
Carcinogen Induced Immunosuppression: A Critical Role for Immature Epidermal Langerhans Cells; Cancer Council of Tasmania (CCT)
Characterising Carcinogen Induced Immunosuppression and Tumor Escape; Cancer Council of Tasmania (CCT)
Collagenolytic enzymes in fish (post-mortem); CSIRO/University of Tasmania (CSIRO/UTAS)
Control of the immune response in disease with emphasis on cancer, autoimmune conditions and stressful situations.; Department of Health and Human Services Tasmania (DHHS)
Cutaneous tolerance induction. Down-regulation of autoimmunity; National Health & Medical Research Council (NHMRC)
Denskometer/2D Database Analysis & IEF System (Proteomics); National Health & Medical Research Council (NHMRC)
Detrimental alterations of antigen presenting cells and T cells during carcinogenesis; Cancer Council of Tasmania (CCT)
Development of the Skin Immune System and the Effect of Exposure to Sunlight; Royal Hobart Hospital Research Foundation (RHHRF)
Do 'classical ' or 'oxidative' UVR-induced DNA adducts drive melanoma induction after ultraviolet radiation; National Health & Medical Research Council (NHMRC)
Down-regulation of Autoimmunity Utilising Modified Dendritic Cells; Clifford Craig Medical Research Trust/UTAS (CCMRT/UTAS)
Effects of physical and chemical carcinogens on Langerhans cell migration and function; Tasmanian Cancer Council (TCC)
Effects of physical and chemical carcinogens on Langerhans cell migration and function; Tasmanian Cancer Council (TCC)
Effects of ultraviolet light on epidermal antigen presenting cell function; University of Tasmania (UTAS)
Effects of UV radiation and vitamin D deficiency on the development of the skin immune system; Cancer Council of Tasmania (CCT)
Elite workstation for Flow Cytometry (single user); National Health & Medical Research Council (NHMRC)
EPICS large laser elite flow cytometer; Clive & Vera Ramaciotti Foundation (CVRF)
Evaluation of the ability of vitamin D and metallothionein to protect against UV-radiation induced skin cancer ; Cancer Council of Tasmania (CCT)
Functional Depletion of Langerhans Cells by Ultraviolet Light: - Mechanisms and a Potential Cure; Cancer Council of Tasmania (CCT)
Funding for Small Equipment - Microradiance Laser Confocal Imaging System; Australian Cancer Research Foundation (ACRF)
Image Analyser; National Health & Medical Research Council (NHMRC)
Immunological changes in Antarctic expedition personnel; Antarctic Science Advisory Committee (ASAC)
Immunosuppression by Carcinogen Induced Immature Dendritic Cells: Gene Activation and Intervention Strategies; Cancer Council of Tasmania (CCT)
Immunosuppression by Carcinogen Induced Immature Dendritic Cells: Signalling Molecules, Potential Pathways and Intervention Strategies; Cancer Council of Tasmania (CCT)
Immunosuppression by Carcinogen Induced Immature Dendritic Cells: Signalling Molecules, Potential Pathways and Intervention Strategies; Cancer Council of Tasmania (CCT)
Induction of immuno-suppression by functionality immature Langerhans cells; Clifford Craig Medical Research Trust/UTAS (CCMRT/UTAS)
Influence of vitamin D and gender on UVB-induced DNA damage, immunoregulation and development of melanoma; Cancer Council of Tasmania (CCT)
Isolation, identification and location of the collagenoltic enzymes that degrade myotendinous junctions in fish (post mortem); CSIRO/University of Tasmania (CSIRO/UTAS)
Langerhans cell migration: effects of UV-B and chemical carconogen; National Health & Medical Research Council (NHMRC)
Langerhans cells in skin cancer; National Health & Medical Research Council (NHMRC)
Long Term Effects of UV-B Irradiation on the Developing Skin Immune System; Cancer Council of Tasmania (CCT)
Long Term Effects of UVB Irradiation on Neonatal Langerhans Cells; Cancer Council of Tasmania (CCT)
Pathophysiological Correlates in Smokers and Smoking Related Chronic Obstructive Pulmonary Disease; National Health & Medical Research Council (NHMRC)
Protection of the brain from infection: Immune properties of olfactory ensheathing cells; Royal Hobart Hospital Research Foundation (RHHRF)
Refrigerated centrifuge for immunological and microbiological studies; National Health & Medical Research Council (NHMRC)
Regulation of lymphocyte entry into the spleen by marginal zone macrophages; National Health & Medical Research Council (NHMRC)
Role of vitamin D3 and metallothionein in protection against melanoma; Cancer Council of Tasmania (CCT)
Scarring and angiogenesis in the airway wall in smoking and COPD: links between inflammation and remodelling; National Health & Medical Research Council (NHMRC)
Skin Tone Measurement by reflectometer versus Melanin Density of the epidermis; National Health & Medical Research Council (NHMRC)
Superspeed Centrifuge.; National Health & Medical Research Council (NHMRC)
The effect of UV radiation and vitamin D deficiency on the development of the skin immune system; Cancer Council of Tasmania (CCT)
The effects of ultraviolet light on Langerhans cell migration & function; Tasmanian Cancer Council (TCC)
The effects of ultraviolet light on Langerhans cell migration and function; Cancer Council of Tasmania (CCT)
The effects of ultraviolet light on langerhans cell migration and function; Tasmanian Cancer Council & W P Holman Clinics (TCC/WPH)
Tolerogenic dendritic cells as a potential therapy for autoimmune disease; Clifford Craig Medical Research Trust/UTAS (CCMRT/UTAS)
Tolerogenic dendritic cells as a potential therapy for autoimmune disease (combined with 106924: Immature cells induce suppressive immune responses); National Health & Medical Research Council (NHMRC)
Ultraviolet light modulates epidermal antigen presenting cell function; National Health & Medical Research Council (NHMRC)
Vitamin D Deficiency in Skin Cancer Development; Royal Hobart Hospital Research Foundation (RHHRF)
Vitamin D in the Skin Immune System; Arthritis Australia (AFA)

Research Candidate Supervision

Analysis of Antigen Handling by Epidermal Langerhans' Cells during the Early Neonatal Period
Anaylysis of antigen hancling by IL-10 induced tolerogenic dendritic cells
Antarctic immunology
Dendritic cell role in leishmaniasis
Denoritic cells in cervical cancer
Dietary Vitamin D3, the Skin Immune System and Implications for Skin Cancer
Effects of stress on the immune system
Evaluate the ability of neonatal Langerhans cells to process and present antigen.
Human Osteoarthrosis- Lectin/Histochemical Studies
Immune Reconstitution in HIV-I Infection- The Effects of Antiretroviral and Immune Therapy
Immunology of langerhans cells
Investigation of the effect of chemical carcinogens upon epidermal and dermal cell populations
Langerhans cell function in skin cancer
Langerhans cell, tobacco smoking and lung tumours
Langerhans cells- from birth to maturity.
Morphological Plasticity of the Developing Central Nervous System in response to injury
Neonatal Exposure to Ultraviolet Radiation- Implications for Development and Function of the Skin Immune System
Title- Post mortem breakdown of the myotendinous junction in fish
To study the effects of ultraviolet light on the skin immune system
Unique Features of the Neonatal Immune System