Web Access Research Portal

Researcher: Fitzgerald, LM (Dr Liesel Fitzgerald)

Research Fields

Cancer Genetics
Medical Genetics (excl. Cancer Genetics)
Epigenetics (incl. Genome Methylation and Epigenomics)
Molecular Targets
Ophthalmology
Oncology and Carcinogenesis
Cancer Cell Biology
Epidemiology
Solid Tumours

Research Impact

Cancer and Related Disorders
Hearing, Vision, Speech and Their Disorders
Urogenital System and Disorders
Inherited Diseases (incl. Gene Therapy)
Health and Support Services
Diabetes
Disease Distribution and Transmission (incl. Surveillance and Response)
Blood Disorders
Nervous System and Disorders
Men's Health

Career Best Publications

Research Publications

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease; Human Molecular Genetics
A three-protein biomarker panel assessed in diagnostic tissue predicts death from prostate cancer for men with localized disease; Cancer Medicine
Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study; International Journal of Cancer
Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features; Clinical Cancer Research
Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels; International Journal of Cancer
Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease; Human Genetics
Association of FGFR4 genetic polymorphisms with prostate cancer risk and prognosis; Prostate Cancer and Prostatic Diseases
Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer; BMC Cancer
Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases; Human Genetics
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation; Nature communications
Blood lipids and prostate cancer: a Mendelian randomization analysis; Cancer Medicine
Broad Phenotypic variability in a Single Pedigree With a Novel 1410delC Mutation in the PST Domain of the PAX6 Gene; Human Mutation
Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG; The Prostate
Clinical Utility of Five Genetic Variants for Predicting Prostate Cancer Risk and Mortality; The Prostate
Dense genome-wide SNP linkage scan in 301 hereditary prostate cancer families identifies multiple regions with suggestive evidence for linkage; Human Molecular Genetics
Does the Addition of Information on Genotype Improve Prediction of the Risk of Melanoma and Nonmelanoma Skin Cancer beyond That Obtained from Skin Phenotype?; American Journal of Epidemiology
Effect of MELANOTAN1, [Nle4 , D-Phe7 ]-a-MSH, on melanin synthesis in humans with MC1R variant alleles; Peptides
Evidence for a Novel Type 1 Diabetes Susceptibility Locus on Chromosome 8; Diabetes
Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L3 region on chromosome 22q12 as a risk locus; Human Molecular Genetics
Genetic Variants in the LEPR, CRY1, RNASEL, IL4, and ARVCF Genes Are Prognostic Markers of Prostate Cancer-Specific Mortality; Cancer Epidemiology, Biomarkers and Prevention
Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21; Human genetics
Genome-wide association study identifies a genetic variant associated with risk for more aggressive prostate cancer; Cancer Epidemiology, Biomarkers and Prevention
Genome-Wide Association Study of Prostate Cancer–Specific Survival; Cancer Epidemiology, Biomarkers and Prevention
Genome-wide linkage analyses of hereditary prostate cancer families with colon cancer provide further evidence for a susceptibility locus on 15q11–q14; European Journal of Human Genetics
Genome-wide measures of DNA methylation in peripheral blood and the risk of urothelial cell carcinoma: a prospective nested case-control study; British Journal of Cancer
Genome-Wide Measures of Peripheral Blood DNA Methylation and Prostate Cancer Risk in a Prospective Nested Case-Control Study; The Prostate
Genome-wide meta-analyses of breast, ovarian, and prostate pancer association studies identify multiple new susceptibility loci shared by at least two cancer types; Cancer Discovery
Genotypic and phenotypic spectrum of X-linked retinoschisis in Australia; Clinical and Experimental Ophthalmology
Germline Missense Variants in the BTNL2 Gene Are Associated with Prostate Cancer Susceptibility; Cancer Epidemiology, Biomarkers and Prevention
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array; Nature Genetics
Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease; European Journal of Human Genetics
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study; Nature Genetics
Interest in genetic testing among affected men from hereditary prostate cancer families and their unaffected male relatives; Genetics in Medicine
Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis; International Journal of Cancer
Investigation of the prevalence of the myocilin Q368STOP mutation in Ugandan glaucoma patients; Ophthalmic Genetics
Investigation of the Relationship Between Prostate Cancer and MSMB and NCOA4 Genetic Variants and Protein Expression; Human Mutation
Linkage analysis of a second large prostate cancer family from southern Tasmania, Australia; American Society of Human Genetics Conference
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans; Human Molecular Genetics
Mutations in a Novel Gene, NHS, Cause the Pleiotropic Effects of Nance-Horan Syndrome, Including Severe Congenital Cataract, Dental Anomalies, and Mental Retardation; American Journal of Human Genetics
Mutations in the NDP gene: contribution to Norrie disease, familial exudative vitreoretinopathy and retinopathy of prematurity; Clinical and Experimental Ophthalmology
National Cancer Institute Prostate Cancer Genetics Workshop; Cancer Research
Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium; British Journal of Cancer
Prediction of Individual Genetic Risk to Prostate Cancer Using a Polygenic Score; PRACTICAL consortium; The Prostate
Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status; Human Molecular Genetics
Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort; BMC Medicine
Reliability of DNA methylation measures from dried blood spots and mononuclear cells using the HumanMethylation450k BeadArray; Scientific Reports
Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 known prostate cancer susceptibility loci; Cancer Epidemiology, Biomarkers and Prevention
Sequence variants of α-methylacyl-CoA racemase are associated with prostate cancer risk: A replication study in an ethnically homogeneous population; The Prostate
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study; Nature Genetics
Testing the Circadian Gene Hypothesis in Prostate Cancer: A Population-Based Case-Control Study; Cancer Research
The advantages of dense marker sets for linkage analysis with very large families; Human Genetics
The OncoArray Consortium: a network for understanding the genetic architecture of common cancers; Cancer Epidemiology, Biomarkers and Prevention
Tools for translational epigenetic studies involving formalin-fixed paraffin-embedded human tissue: applying the Infinium HumanMethyation450 Beadchip assay to large population-based studies; BMC Research Notes
Use of a novel non-parametric version of DEPTH to identify genomic regions associated with prostate cancer risk; Cancer Epidemiology, Biomarkers and Prevention
Use of Aspirin and Other Nonsteroidal Antiinflammatory Medications in Relation to Prostate Cancer Risk; American Journal of Epidemiology
Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG); Human Genetics
Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes; OncoTarget

Research Projects

Identification of Genomic Regions Implicated in Hereditary Prostate Cancer in Tasmania by Genome-wide Scan; Royal Hobart Hospital Research Foundation (RHHRF)
Investigation of chromosomal loss and gain at 7p21 in a Tasmanian hereditary prostate cancer family; Royal Hobart Hospital Research Foundation (RHHRF)
Identifying biomarkers associated with clinically significant and fatal prostate cancer through genome-wide mRNA expression and methylation analyses
Targeted next-generation sequencing of the hereditary prostate cancer locus 15q13-q14

Research Candidate Supervision