Fields of Research

Rheumatology and arthritis
Epidemiology
Clinical pharmacology and therapeutics
Pharmaceutical sciences
Clinical sciences
Medical biochemistry - nucleic acids
Endocrinology
Radiology and organ imaging
Geriatrics and gerontology
Pain
Orthopaedics
Genetics
Higher education
Image processing
Primary health care
Cellular nervous system
Autoimmunity
Traditional, complementary and integrative medicine
Health economics
Clinical nutrition
Respiratory diseases
Aged health care
Preventative health care
Modelling and simulation
Applied statistics

Research Objectives

Clinical health
Diagnosis of human diseases and conditions
Health related to ageing
Treatment of human diseases and conditions
Human pain management
Other health
Prevention of human diseases and conditions
Women's and maternal health
Determinants of health
Evaluation of health outcomes
Preventive medicine
Public health (excl. specific population health)
Occupational health
Expanding knowledge in the health sciences
Efficacy of medications
Assessment, development and evaluation of curriculum
Disease distribution and transmission (incl. surveillance and response)
Expanding knowledge in the mathematical sciences

Career Best Publications

A longitudinal study of the association between infrapatellar fat pad maximal area and changes in knee symptoms and structure in older adults; ARD Online
Association between childhood overweight measures and adulthood knee pain, stiffness and dysfunction: a 25-year cohort study; ARD Online
Association between leptin, body composition, sex and knee cartilage morphology in older adults: the Tasmanian Older Adult Cohort (TASOAC) study; Annals of the Rheumatic Diseases
Association between MRI-detected knee joint regional effusion-synovitis and structural changes in older adults: a cohort study; Annals of The Rheumatic Diseases: The Eular Journal
Associations between serum levels of inflammatory markers and change in knee pain over 5 years in older adults: a prospective cohort study; Annals of The Rheumatic Diseases
Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study; Journal of Clinical and Endocrinology
Effect of vitamin D supplementation on tibial cartilage volume and knee pain among patients with symptomatic knee osteoarthritis: a randomized clinical trial; Journal of The American Medical Association
Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II breakdown; Osteoarthritis and Cartilage
Natural History of Knee Cartilage Defects and Factors Affecting Change; Archives of Internal Medicine
Serum Levels of Vitamin D, Sunlight Exposure, and Knee Cartilage Loss in Older Adults; Arthritis and Rheumatism
Signal intensity alteration in the infrapatellar fat pad at baseline for the prediction of knee symptoms and structure in older adults: a cohort study; ARD Online
Smoking interacts with family history with regard to change in knee cartilage volume and cartilage defect development; Arthritis & Rheumatism

Research Publications

A family history of knee joint replacement increases the progression of knee radiographic osteoarthritis and medial tibial cartilage volume loss over 10 years; Osteoarthritis and Cartilage
A large infrapatellar fat pad protects against knee pain and lateral tibial cartilage volume loss; Arthritis Research & Therapy
A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee; Arthritis Research & Therapy
A longitudinal study of the association between infrapatellar fat pad maximal area and changes in knee symptoms and structure in older adults; ARD Online
A longitudinal study of the association between knee alignment and change in cartilage volume and chondral defects in a largely non-osteoarthritic population; Journal of Rheumatology
A longitudinal study of the effect of sex and age on rate of change in knee cartilage volume in adults; Rheumatology
A novel method for assessing proximal tibiofibular joint on MR images in patients with knee osteoarthritis; Osteoarthritis and Cartilage
A novel method for assessing signal intensity within infrapatellar fat pad on MR images in patients with knee osteoarthritis; Osteoarthritis and Cartilage
A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia; Osteoarthritis and Cartilage
A prospective study of the associations between 25-hydroxy-vitamin D, sarcopenia progression and physical activity in older adults; Clinical Endocrinology
A Randomised Controlled Trial of YOGa and Strengthening Exercise for Knee OsteoArthritis: Protocol for a Comparative Effectiveness Trial (YOGA Trial); Journal of Functional Morphology and Kinesiology
ABT-874, a fully human monoclonal anti-IL-12/IL-23 antibody for the potential treatment of autoimmune diseases; Current Opinion in Investigational Drugs
Ambulatory activity interacts with common risk factors for osteoarthritis to modify increases in MRI-detected osteophytes; Osteoarthritis and Cartilage
AMPK signaling in energy control, cartilage biology, and osteoarthritis; Frontiers in Cell and Developmental Biology
Anti-interleukin-6 receptor antibody treatment in inflammatory autoimmune diseases
Application of Artificial Neural Networks in Automatic Cartilage Segmentation; International Workshop on Advanced Computational Intelligence
Aspirin is associated with reduced cartilage loss in knee osteoarthritis: Data from a cohort study; Maturitas
Assessing the function of the ZFP90 variant rs1170426 in SLE and the association between SLE drug target and susceptibility genes; Frontiers in Immunology
Association between GDF5 rs143383 polymorphism and knee osteoarthritis: an updated meta-analysis based on 23,995 subjects; BMC Musculoskeletal Disorders
Association between age and knee structural change: a cross sectional MRI based study; Annals of the Rheumatic Diseases
Association between childhood overweight measures and adulthood knee pain, stiffness and dysfunction: a 25-year cohort study; ARD Online
Association between circulating adipokines, radiographic changes, and knee cartilage volume in patients with knee osteoarthritis; Scandinavian Journal of Rheumatology
Association between DEFB103 gene copy number variation and ankylosing spondylitis: A case-control study; Tissue Antigens
Association between diet quality in adolescence and adulthood and knee symptoms in adulthood: a 25-year cohort study; The British Journal of Nutrition
Association between hip and knee cartilage measured using radiographs and magnetic resonance imaging: the Tasmanian Older Adult Cohort Study; Rheumatology
Association between infrapatellar fat pad volume and knee structural changes in patients with knee osteoarthritis; Journal of Rheumatology
Association between knee symptoms, change in knee symptoms over 6-9 years, and SF-6D health state utility among middle-aged Australians; Quality of Life Research
Association between knee symptoms, change in knee symptoms over 6–9 years, and SF-6D health state utility among middle-aged Australians
Association between leptin, body composition, sex and knee cartilage morphology in older adults: the Tasmanian Older Adult Cohort (TASOAC) study; Annals of the Rheumatic Diseases
Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study; Arthritis Research & Therapy
Association between metabolic syndrome and trajectories of knee pain: a 10.7 year follow-up study
Association between MRI-detected knee joint regional effusion-synovitis and structural changes in older adults: a cohort study; Annals of The Rheumatic Diseases: The Eular Journal
Association between MRI-detected osteophytes and changes in knee structures and pain in older adults: a cohort study; Osteoarthritis and Cartilage
Association between osteoarthritis-related serum biochemical markers over 11 years and knee MRI-based imaging biomarkers in middle-aged adults; Osteoarthritis and Cartilage
Association Between Pain at Sites Outside the Knee and Knee Cartilage Volume Loss in Elderly People Without Knee Osteoarthritis: A Prospective Study; Arthritis Care & Research
Association between popliteal artery wall thickness and structural progression in patients with symptomatic knee osteoarthritis; Rheumatology
Association between quantitatively measured infrapatellar fat pad high signal intensity alteration and MRI-assessed progression of knee osteoarthritis; Arthritis Care & Research
Association between serum levels of 25-hydroxyvitamin D and osteoarthritis: a systematic review; Rheumatology: The Interdisciplinary Concept
Association of ACE Gene Polymorphism with Genetic Susceptibility to Systemic Lupus Erythematosus in a Chinese Population: A Family-based Association Study; The Journal of Rheumatology
Association of adiposity measures in childhood and adulthood with knee cartilage thickness, volume and bone area in young adults; International Journal of Obesity
Association of baseline knee bone size, cartilage volume, and body mass index with knee cartilage loss over time: a longitudinal study in younger or middle-aged adults; Journal of Rheumatology
Association of beta-defensin gene copy number variations with ankylosing spondylitis in Chinese population: A case-control study; Modern Rheumatology
Association of body composition and hormonal and inflammatory factors with tibial cartilage volume and sex difference in cartilage volume in young adults; Arthritis Care & Research
Association of body composition, physical activity and physical performance with knee cartilage thickness and bone area in young adults; Rheumatology
Association of cartilage defects are associated with loss of knee cartilage in healthy, middle-age adults: prospective study; Arthritis & Rheumatism
Association of childhood adiposity measures with adulthood knee cartilage defects and bone marrow lesions: a 25-year cohort study; Osteoarthritis and Cartilage
Association of glucose homeostasis and metabolic syndrome with knee cartilage defects and cartilage volume in young adults; Seminars in Arthritis and Rheumatism
Association of patellar bone marrow lesions with knee pain, patellar cartilage defect and patellar cartilage volume loss in older adults: a cohort study; Osteoarthritis and Cartilage
Association of physical activity and physical performance with tibial cartilage volume and bone area in young adults; Arthritis Research & Therapy
Association of prevalent and incident knee cartilage defects with loss of tibial and patellar cartilage; Arthritis and Rheumatism
Association of serum levels of inflammatory markers and adipokines with joint symptoms and structures in participants with knee osteoarthritis; Rheumatology
Associations between circulating adipokines and bone mineral density in patients with knee osteoarthritis: a cross-sectional study; BMC Musculoskeletal Disorders
Associations between diet quality and knee joint structures, symptoms and systemic abnormalities in people with symptomatic knee osteoarthritis; Clinical Nutrition
Associations between dietary intake of vitamin K and changes in symptomatic and structural changes in patients with knee osteoarthritis; Arthritis Care & Research
Associations between endogenous sex hormones and MRI structural changes in patients with symptomatic knee osteoarthritis; Osteoarthritis and Cartilage
Associations between fat mass and multi-site pain: A 5-year longitudinal study; Arthritis Care & Research
Associations between knee effusion-synovitis and joint structural changes in patients with knee osteoarthritis; Journal of Rheumatology
Associations between knee structural measures, circulating inflammatory factors and MMP13 in patients with knee osteoarthritis; Osteoarthritis and Cartilage
Associations between MRI-detected early osteophytes and knee structure in older adults: a population-based cohort study; Osteoarthritis and Cartilage
Associations between proximal tibiofibular joint (PTFJ) types and knee osteoarthritic changes in older adults; Osteoarthritis and Cartilage
Associations between serum 25-hydroxyvitamin D and disease activity, inflammatory cytokines and bone loss in patients with rheumatoid arthritis; Rheumatology
Associations between serum ghrelin and knee symptoms, joint structures and cartilage or bone biomarkers in patients with knee osteoarthritis; Osteoarthritis and Cartilage
Associations between serum IL-8 and knee symptoms, joint structures, and cartilage or bone biomarkers in patients with knee osteoarthritis; Clinical Rheumatology
Associations between serum levels of inflammatory markers and change in knee pain over 5 years in older adults: a prospective cohort study; Annals of The Rheumatic Diseases
Associations between serum S100A8/S100A9 and knee symptoms, joint structures and cartilage enzymes in patients with knee osteoarthritis; Osteoarthritis and Cartilage
Associations between suprapatellar pouch effusion-synovitis, serum cartilage oligomeric matrix protein, high sensitivity C-reaction protein, knee symptom, and joint structural changes in patients with knee osteoarthritis; Clinical Rheumatology
Associations between systemic bone mineral density, knee cartilage defects and bone marrow lesions in patients with knee osteoarthritis; International Journal of Rheumatic Diseases
Associations between the genetic polymorphisms of MTHFR and outcomes of methotrexate treatment in rheumatoid arthritis; Clinical and Experimental Rheumatology
Associations between the morphological parameters of proximal tibiofbular joint (PTFJ) and changes in tibiofemoral joint structures in patients with knee osteoarthritis; Arthritis Research & Therapy
Associations between vitamin D receptor gene polymorphisms and ankylosing spondylitis in Chinese Han population: a case-control study; Osteoporosis International
Associations between vitamin D receptor gene polymorphisms and osteoarthritis: an updated meta-analysis; Rheumatology: The Interdisciplinary Concept
Associations of blood pressure and arterial stiffness with knee cartilage volume in patients with knee osteoarthritis; Rheumatology (United Kingdom)
Associations of serum citrate levels with knee structural changes and cartilage enzymes in patients with knee osteoarthritis; International Journal of Rheumatic Diseases
Associations of the IL-1F7 gene polymorphisms with rheumatoid arthritis in Chinese Han population; International Journal of Immunogenetics
Autophagy-related IRGM genes confer susceptibility to ankylosing spondylitis in a Chinese female population: a case-control study; Genes and Immunity
B-cell-targeted therapy for systemic lupus erythematosus: an update
Belimumab - An anti-BLyS human monoclonal antibody for rheumatoid arthritis; Expert Opinion on Biological Therapy
Belimumab Human Genome Sciences/Cambridge Antibody Technology/GlaxoSmithKline
Belimumab Therapy for Systemic Lupus Erythematosus and Potential Treatment of Rheumatoid Arthritis; Drug Development Research
Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases
Bertilimumab Cambridge Antibody Technology Group
Body fat is associated with increased and lean mass with decreased knee cartilage loss in older adults: a prospective cohort study; International Journal of Obesity
Body fat predicts an increase and limb muscle strength predicts a decrease in leptin in older adults over 2.6 years; Clinical Endocrinology
Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults; Arthritis Research & Therapy
Boswellia for osteoarthritis (Protocol); Cochrane Database of Systematic Reviews
Cartilage signal intensity on T1-weighted MRI: association with risk factors and measures of knee osteoarthritis; Clinical Rheumatology
Change in knee structure and change in tibiofemoral joint space width: a five year longitudinal population–based study; BMC Musculoskeletal Disorders
Characterizing and validating the phenotype of knee pain: a latent class analysis
Childhood physical performance measures predict adulthood knee cartilage volume and bone area: A 25-year cohort study; Arthritis Care & Research
Circulating C reactive protein in osteoarthritis: a systematic review and meta-analysis; ARD Online
Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults; Osteoarthritis and Cartilage
Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study; Journal of Clinical and Endocrinology
Correlates of Hip Cartilage Defects: A Cross-sectional Study in Older Adults; Journal of Rheumatology
Correlates of knee bone marrow lesions in younger adults; Arthritis Research & Therapy
Correlates of knee pain in older adults: Tasmanian Older Adult Cohort Study; Arthritis and Rheumatism
Correlates of knee pain in younger subjects; Clinical Rheumatology
Correlates of Subchondral BMD: A Cross-Sectional Study; Journal of Bone and Mineral Research
Correlation between changes in global knee structures assessed on Magnetic Resonance Imaging and radiographic osteoarthritis changes over 10 years in a mid-life cohort; Arthritis Care & Research
Cross-sectional and longitudinal associations between circulating leptin and knee cartilage thickness in older adults; Annals of the Rheumatic Diseases: The Euler Journal
Cross-sectional and longitudinal associations between knee joint effusion synovitis and knee pain in older adults; Journal of Rheumatology
Cross-sectional and longitudinal associations between serum inflammatory cytokines and knee bone marrow lesions in patients with knee osteoarthritis; Osteoarthritis and Cartilage
Cross-sectional and longitudinal associations between serum levels of high-sensitivity C-reactive protein, knee bone marrow lesions, and knee pain in patients with knee osteoarthritis; Arthritis Care & Research
Cross-sectional and longitudinal associations between systemic, subchondral bone mineral density and knee cartilage thickness in older adults with or without radiographic osteoarthritis; Annals of the Rheumatic Diseases: The Euler Journal
Current status and future prospects for disease modification in osteoarthritis; Rheumatology
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression; EBioMedicine
Depression in patients with knee osteoarthritis: risk factors and associations with joint symptoms; BMC Musculoskeletal Disorders
Determinants of trajectories of multi-site pain in knee osteoarthritis: a 10.7-year prospective study in older adults; Annual European Congress of Rheumatology
Development and formulation of the classification criteria for osteoarthritis; Annals of Translational Medicine
Do early life factors affect the development of knee osteoarthritis in later life: a narrative review; Arthritis Research & Therapy
Do NSAIDs Affect Longitudinal Changes in Knee Cartilage Volume and Knee Cartilage Defects in Older Adults?; The American Journal of Medicine
Do NSAIDs Affect the Progression of Osteoarthritis?; Inflammation
Does cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss?; BMC Musculoskeletal Disorders
Does diclofenac induce accelerated progression of hip and knee radiographic osteoarthritis? Comment on the article by Reijman et al
Does smoking reduce the progression of osteoarthritis? Meta-analysis of observational studies; Arthritis Care & Research
Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? Study protocol for a randomised controlled trial; Trials
Does weight in the offspring of people with a total knee replacement for severe primary knee osteoarthritis have a more detrimental effect on knee cartilage and pain? A 10-year prospective study
Drug evaluation: VX-702, a MAP kinase inhibitor for rheumatoid arthritis and acute coronary syndrome
Early radiographic osteoarthritis is associated with substantial changes in cartilage volume and tibial bone surface area in both males and females; Osteoarthritis and Cartilage
Effect of 1,25-(OH)₂D₃ on proliferation of fibroblast-like synoviocytes and expressions of pro-inflammatory cytokines through regulating MicroRNA-22 in a rat model of rheumatoid arthritis; Cellular Physiology and Biochemistry
Effect of atorvastatin on knee cartilage volume in patients with symptomatic knee osteoarthritis: results from a randomized placebo-controlled trial; Arthritis and Rheumatology
Effect of atorvastatin on skeletal muscles of patients with knee osteoarthritis: Post-hoc analysis of a randomised controlled trial; Frontiers in Medicine
Effect of vitamin D supplementation on aortic stiffness and arterial hemodynamics in people with osteoarthritis and vitamin D deficiency; Journal of the American College of Cardiology
Effect of vitamin D supplementation on depressive symptoms in patients with knee osteoarthritis; Journal of The American Medical Directors Association
Effect of vitamin D supplementation on pain and physical function in patients with knee osteoarthritis (OA): An OA Trial Bank protocol for a systematic review and individual patient data (IPD) meta-analysis; BMJ Open
Effect of vitamin D supplementation on tibial cartilage volume and knee pain among patients with symptomatic knee osteoarthritis: a randomized clinical trial; Journal of The American Medical Association
Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis : a randomized trial; Annals of Internal Medicine
Effects of infrapatellar fat pad preservation versus resection on clinical outcomes after total knee arthroplasty in patients with knee osteoarthritis (IPAKA): Study protocol for a multicentre, randomised, controlled clinical trial; BMJ Open
Effects of vitamin D supplementation on disabling foot pain in patients with symptomatic knee osteoarthritis; Arthritis Care & Research
Efficacy and cost-effectiveness of stem cell injections for symptomatic relief and structural improvement in people with Tibiofemoral knee OsteoaRthritis: Protocol for a randomised placebo-controlled trial (the SCUlpTOR trial); BMJ Open
Efficacy and safety of turmeric extracts for the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomised controlled trials; Current Rheumatology Reports
Factors affecting progression of knee cartilage defects in normal subjects over 2 years; Rheumatology
Factors association with hip cartilage volume measured by magnetic resonance imaging. The Tasmanian Older Adult Cohort Study; Arthritis & Rheumatism
Familial effects on structural changes relevant to knee osteoarthritis: a prospective cohort study; Osteoarthritis and Cartilage
Familial, structural, and environmental correlates of MRI-defined bone marrow lesions: a sibpair study; Arthritis Research & Therapy
Genetic mechanisms of knee osteoarthritis: a population based case-control study; Annals of the Rheumatic Diseases
Genetic mechanisms of knee osteoarthritis: a population-based longitudinal study; Arthritis Research & Therapy
Guidelines for the diagnosis and treatment of osteoarthritis in China (2019 edition); Annals of Translational Medicine
Higher serum levels of resistin are associated with knee synovitis and structural abnormalities in patients with symptomatic knee osteoarthritis; Journal of the American Medical Directors Association
History of knee injury and MRI-assessed knee structures in middle- and older-aged adults: a cross-sectional study; Clinical Rheumatology
How do MRI-detected subchondral bone marrow lesions (BMLs) on two different MRI sequences correlate with clinically important outcomes?; Calcified Tissue International
How important is MRI for detecting early osteoarthritis?; Nature Clinical Practice Rheumatology
Hypointense signals in the infrapatellar fat pad assessed by magnetic resonance imaging are associated with knee symptoms and structure in older adults: a cohort study; Arthritis Research & Therapy
Identification of early knee osteoarthritis - a new horizon; Current Rheumatology Reviews
Implementation of telemedicine for knee osteoarthritis: Study protocol for a randomized controlled trial; Trials
Infra Patellar Fat Pad Signal Intensity Alterations and Effusion-Synovitis Predict Knee Pain, Cartilage Volume Loss and Total Knee Replacement over 10.7 Years in Older Adults
Infrapatellar fat pad in the knee: Is local fat good or bad for knee osteoarthritis?; Arthritis Research & Therapy
Internationalisation Strategy Benchmarking Final Report and Recommendations
Investigational drugs for the treatment of osteoarthritis; Expert Opinion on Investigational Drugs
Investigational drugs for the treatment of osteoarthritis, an update on recent developments; Expert opinion on investigational drugs
Knee and hip radiographic osteoarthritis predict total hip bone loss in older adults: a prospective study; Journal of Bone and Mineral Research
Knee Articular Cartilage Development in Children: A Longitudinal Study of the Effect of Sex, Growth, Body Composition, and Physical Activity; Pediatric Research
Knee cartilage defects in a sample of older adults: natural history, clinical significance and factors influencing change over 2.9 years; Osteoarthritis and Cartilage
Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II breakdown; Osteoarthritis and Cartilage
Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis; Osteoarthritis and Cartilage
Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume; Arthritis Research & Therapy
Knee structural alteration and BMI: A cross-sectional study; Obesity Research
Knee structural alteration and body mass index: a cross-sectional study; Obesity Research
Leflunomide, a new disease-modifying drug for treating active rheumatoid arthritis in methotrexate-controlled phase II clinical trial; Chinese Medical Journal
Licofelone (Merckle)
Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years
Longitudinal association of infrapatellar fat pad signal intensity alteration with biochemical biomarkers in knee osteoarthritis; Rheumatology
Longitudinal associations between adiposity and change in knee pain: Tasmanian older adult cohort study; Seminars in Arthritis and Rheumatism
Lumirocoxib (Novatis)
Magnetic resonance imaging markers as predictors for total knee replacement over 10.7 years in older adults
Maintaining vitamin D sufficiency is associated with improved structural and symptomatic outcomes in knee osteoarthritis; American Journal of Medicine
Mass effect and signal intensity alteration in the suprapatellar fat pad: associations with knee symptoms and structure; Osteoarthritis and Cartilage
Measurement of volume-occupying rate of cervical spinal canal and its role in cervical spondylotic myelopathy; European Spine Journal
Meniscal extrusion predicts increases in subchondral bone marrow lesions and bone cysts and expansion of subchondral bone in osteoarthritic knees; Rheumatology
Meniscal tear and increased tibial plateau bone area in healthy post-menopausal women; Osteoarthritis and Cartilage
Meniscal Tear as an Osteoarthritis Risk Factor in a Largely Non-Osteoarthritic Cohort: A Cross-Sectional Study; Journal of Rheumatology
Metabolic triggered inflammation in osteoarthritis; Osteoarthritis and Cartilage
Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study; Annals of the Rheumatic Diseases
Monoclonal antibodies for the treatment of osteoarthritis; Expert Opinion on Biological Therapy
MRI-based texture analysis of infrapatellar fat pad to predict knee osteoarthritis incidence; Radiology
MRI-detected osteophytes of the knee: natural history and structural correlates of change; Arthritis Research & Therapy
Multi-omics analysis of copy number variations of RNA regulatory genes in soft tissue sarcoma; Life Sciences
Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort; BMC Musculoskeletal Disorders
Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults; Arthritis Research & Therapy
Natural history of areal bone marrow lesions; Osteoarthritis Research Society International
Natural History of Knee Cartilage Defects and Factors Affecting Change; Archives of Internal Medicine
New trends in pharmacological treatments for osteoarthritis; Frontiers in Pharmacology
Not a simple fat-soluble vitamin: changes in serum 25-(OH)D levels are predicted by adiposity and adipocytokines in older adults; Journal of Internal Medicine
Optimal sampling of MRI slices for the assessment of knee cartilage volume for cross-sectional and longitudinal studies; BMC Musculoskeletal Disorders
Oral administration of type II collagen suppresses pro-inflammatory mediator production by synoviocytes in rats with adjuvant arthritis; Clinical and Experimental Immunology
Osteoarthritis and cartilage defects: does size matter
Osteoarthritis bone marrow lesions at the knee and large artery characteristics; Osteoarthritis and Cartilage
Patellar tendon enthesis abnormalities and their association with knee pain and structural abnormalities in older adults; Osteoarthritis and Cartilage
Patellofemoral bone marrow lesions: natural history and associations with pain and structure; Arthritis Care & Research
Pathogenic variants screening in seventeen candidate genes on 2p15 for association with ankylosing spondylitis in a Han Chinese population; PLoS ONE
Pharmacotherapy for knee osteoarthritis: current and emerging therapies; Expert Opinion on Pharmacotherapy
Physical Activity and Knee Structural Change: A Longitudinal Study Using MRI; Medicine and Science in Sports and Exercise
Plasma lipoprotein-associated phospholipase A2 and superoxide dismutase are independent predicators of cognitive impairment in cerebral small vessel disease patients: diagnosis and assessment; Aging and Disease
Popliteal cysts and subgastrocnemius bursitis are associated with knee symptoms and structural abnormalities in older adults: a cross-sectional study; Arthritis Research and Therapy
Predictive value of the morphology of proximal tibiofibular joint for total knee replacement in patients with knee osteoarthritis; Journal of Orthopaedic Research
Predictors of clinical response to intra-articular Hylan injections - a prospective study using synovial fluid parameters, clinical outcomes and magnetic resonance imaging; Journal of Rheumatology
Prevalence and clinical significance of residual or reconverted red bone marrow on knee MRI; Diagnostics
Qualitative and quantitative measures of prefemoral and quadriceps fat pads are associated with incident radiographic osteoarthritis: data from the Osteoarthritis Initiative; Osteoarthritis and Cartilage
Quantitative assessment of knee effusion-synovitis assessment in older adults: Associations with knee structural abnormalities; Arthritis & Rheumatology
Quantitative signal intensity alteration in infrapatellar fat pad predicts incident radiographic osteoarthritis: the Osteoarthritis Initiative; Arthritis Care & Research
Radiographic osteoarthritis and pain are independent predictors of knee cartilage loss: a prospective study; Internal Medicine Journal
Reply Letter to the Editor: Knee joint replacement and individual susceptibility for progression of knee osteoarthritis and tibial cartilage volume loss: not only genes run in the family; Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International
Reply to letter by Hayashi et al. commenting on choice of pulse sequences for MRI based semi-quantitative assessment of cartilage defects ; Arthritis & Rheumatism
Response to ‘Infrapatellar fat pad maximal area and changes in knee symptoms: genderrelated difference or gender difference in reporting?’ by Bai et al; Annals of The Rheumatic Diseases: The Eular Journal
Response to: ‘The role of infrapatellar fat pad resection in total knee arthroplasty’ by White et al; Annals of The Rheumatic Diseases
Responsiveness of Magnetic Resonance Imaging-derived Measures Over 2.7 Years; Journal of Rheumatology
Serum Levels of Interleukin-17 and Adiponectin Are Associated with Infrapatellar Fat Pad Volume and Signal Intensity Alternation in Patients with Knee Osteoarthritis; Arthritis Research & Therapy
Serum levels of resistin and interleukin-17 are associated with increased cartilage defects and bone marrow lesions in patients with knee osteoarthritis; Modern Rheumatology
Serum Levels of Vitamin D, Sunlight Exposure, and Knee Cartilage Loss in Older Adults; Arthritis and Rheumatism
Sex differences in knee cartilage volume in adults: role of body and bone size, age and physical activity; Rheumatology
Signal intensity alteration and maximal area of pericruciate fat pad are associated with incident radiographic osteoarthritis: data from the Osteoarthritis Initiative; European Radiology
Signal intensity alteration in the infrapatellar fat pad at baseline for the prediction of knee symptoms and structure in older adults: a cohort study; ARD Online
Signal intensity alteration within infrapatellar fat pad predicts knee replacement within 5 years: data from the Osteoarthritis Initiative; Osteoarthritis and Cartilage
Single nucleotide polymorphisms of the interleukin-33 (IL-33) gene are associated with ankylosing spondylitis in Chinese individuals: a case-control pilot study; Scandinavian Journal of Rheumatology
Smoking interacts with family history with regard to change in knee cartilage volume and cartilage defect development; Arthritis & Rheumatism
Static Knee Alignment Is Associated with the Risk of Unicompartmental Knee Cartilage Defects; Journal of Orthopaedic Research
Strontium ranelate, a promising disease modifying osteoarthritis drug; Expert Opinion on Investigational Drugs
Subchondral Bone and Cartilage Damage - A Prospective Study in Older Adults; Arthritis and Rheumatism
Systemic and local adipose tissue in knee osteoarthritis; Osteoarthritis and Cartilage
Targeting IL-6 in the treatment of inflammatory and autoimmune diseases
Technology evaluation: MRA, Chugai; Current Opinion in Molecular Therapeutics
Test-retest reliability of measurements of abdominal and multifidus muscles using ultrasound imaging in adults aged 50-79 years; Musculoskeletal Science and Practice
The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study; Arthritis Research & Therapy
The association between objectively measured physical activity and knee structural change using MRI; Annals of the Rheumatic Diseases
The association between oral contraceptive use, bone mineral density and fractures in women aged 50-80 years; Contraception
The association between parity and knee cartilage in young women; Rheumatology
The associations between parity, other reproductive factors and cartilage in women aged 50-80 years; Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International
The clinical correlates of articular cartilage defects in symptomatic knee osteoarthritis: a prospective study; Rhuematology
The clinical significance, natural history and predictors of bone marrow lesion change over eight years; Arthritis Research & Therapy
The cross-sectional and longitudinal associations of dietary patterns with knee symptoms and MRI detected structure in patients with knee osteoarthritis; Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International
The genetic contribution and relevance of knee cartilage defects: Case-control and sib-pair studies; Journal of Rheumatology
The genetic contribution to longitudinal changes in knee structural and muscle strength: A Sibpair Study; Arthritis & Rheumatism
The Genetic Contribution to Muscle Strength, Knee Pain, Cartilage Volume, Bone Size, and Radiographic Osteoarthritis; Arthritis and Rheumatism
The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials; Osteoarthritis and Cartilage
The interaction between weight and family history of total knee replacement with knee cartilage: a 10-year prospective study; Osteoarthritis and Cartilage
The interactions between MRI-detected osteophytes and bone marrow lesions or effusion-synovitis on knee symptom progression: an exploratory study; Osteoarthritis and Cartilage
The lncRNA PILA promotes NF-κB signaling in osteoarthritis by stimulating the activity of the protein arginine methyltransferase PRMT1; Science Signaling
The morphology of proximal tibiofibular joint (PTFJ) predicts incident radiographic osteoarthritis: data from Osteoarthritis Initiative; Osteoarthritis and Cartilage
The natural history of cartilage defects in people with knee osteoarthritis; Osteoarthritis and Cartilage
The offspring of people with a total knee replacement for severe primary knee osteoarthritis have a higher risk of worsening knee pain over 8 years; ARD Online
The relationship between meniscal pathology and osteoarthritis depends on the type of meniscal damage visible on magnetic resonance images: data from the Osteoarthritis Initiative; Osteoarthritis and Cartilage
Tibial subchondral bone size and knee cartilage defects: relevance to knee osteoarthritis; Osteoarthritis and Cartilage
Tilmacoxib (Japan Tobacco)
Tocilizumab: a review of its safety and efficacy in rheumatoid arthritis; Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
Treatment with Etanercept in a Patient with Rheumatoid Arthritis-Associated Interstitial Lung Disease; Clinical Medicine Insights: Case Reports
Two-year prospective longitudinal study exploring the factors associated with change in femoral cartilage volume in a cohort largely without knee radiographic osteoarthritis; Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International
Tyrosine kinase inhibitors for the treatment of rheumatoid arthritis: phase I to II clinical trials; Expert Opinion on Investigational Drugs
Use magnetic resonance imaging to assess articular cartilage; Therapeutic Advances in Musculoskeletal Disease
Use of imaging techniques to predict progression in osteoarthritis
Vitamin D and osteoarthritis: disparity between observational studies and clinical trials; International Journal of Rheumatic Diseases
Vitamin D deficiency in joint pain: Effects of vitamin D supplementation; Nutritional Modulators of Pain in the Aging Population
Vitamin D supplementation and inflammatory and metabolic biomarkers in patients with knee osteoarthritis: post hoc analysis of a randomised controlled trial; British Journal of Nutrition
Vitamin D Supplementation in Patients with Osteoarthritis; Journal of The American Medical Association
Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial; Trials
Vitamin D supplements for trunk muscle morphology in older adults: secondary analysis of a randomized controlled trial; Journal of Cachexia, Sarcopenia and Muscle
What can we learn about osteoarthritis by studying a healthy person against a person with early onset of disease?; Current Opinion in Rheumatology
What Is the Effect of Physical Activity on the Knee Joint? A Systematic Review; Medicine and Science in Sports and Exercise
Which factors associate with localized knee pain and generalized pain: A 10-year longitudinal study?; Arthritis & Rheumatology
Which subchondral bone measure is the best predictor of cartilage damage?

Research Projects

A long-term follow-up of the offspring cohort; National Health & Medical Research Council (NHMRC)
Are Bone Turnover Biomarkers Associated with Knee Structural Change Assessed by Magnetic Resonance Imaging (MRI) in the Elderly?; University of Tasmania (UTAS)
Are Serum Inflammatory Markers Predictive of Knee Structural Changes and Bone Loss in the Elderly? The TASOAC Study; Tasmanian Community Fund (TasCF)
Associations of physical activity, physical performance measures and obesity in childhood with knee cartilage thickness in adults after 25 years; University of Tasmania (UTAS)
Childhood and adulthood determinants knee cartilage health assessed using biomarkers; Royal Hobart Hospital Research Foundation (RHHRF)
Does childhood physical activity, fitness and fatness impact on knee structural change 20 years later?; National Health & Medical Research Council (NHMRC)
Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? A multicentre randomised, double-blind, placebo-controlled trial; National Health & Medical Research Council (NHMRC)
Does vitamin D supplementation have a long-term effect on symptoms of knee osteoarthritis: a 5 years follow up; Tasmanian Community Fund (TasCF)
Does vitamin D supplementation have long-term effect on inflammatory makers in knee osteoarthritis patients.; Royal Hobart Hospital Research Foundation (RHHRF)
Does vitamin D supplementation prevent progression of knee osteoarthritis? A randomised controlled trial; National Health & Medical Research Council (NHMRC)
Emerging Researchers in Ageing (ERA) 2013 Exchange Program; ARC Centre of Excellence in Population Ageing Research (CEPAR)
Longitudinal studies of knee osteoarthritic changes using magnetic resonance imaging; National Health & Medical Research Council (NHMRC)
MicroRNAs in knee osteoarthritis; Arthritis Australia (AFA)
Rising Stars Programme - Changhai Ding; University of Tasmania (UTAS)
Stem Cells as a symptom- and strUcture-modifying Treatment for knee OsteoaRthritis- the SCUlpTOR trial.; National Health & Medical Research Council (NHMRC)
Translational Research in Osteoarthritis: From Epidemiological Studies to Clinical Interventions; Australian Research Council (ARC)
Vitamin D Effects on Osteoarthritis: A Randomised Control Trial; Arthritis Australia (AFA)
Vitamin D Status, Knee Structural Change, Fall Risk and Change in Bone Density...in TASAOC; Arthritis Australia (AFA)
. Clinical trial of nimesulide in the treatment of rheumatoid arthritis and osteoarthritis.
Clinical trial of Actarit in the treatment of rheumatoid arthritis
Clinical trial of diclofenac sodium gel in the treatment of rheumatoid arthritis and osteoarthritis.
Clinical trial of Etofesalamide ointment, a class I new drug, in the treatment of neurodermatitis, chronic eczema and acne vulgaris
Clinical trial of Leflunomide in the treatment of rheumatoid arthritis.
Clinical trial of meloxicam in the treatment of rheumatoid arthritis and osteoarthritis.
Clinical trial of oxaprozin in the treatment of rheumatoid arthritis and osteoarthritis.
Effect of collagen II on adjuvant- and collagen-induced arthritis and its mechanism in rats
Effect of meloxicam gel on adjuvant arthritis in rats
Effect of TGP (a Chinese herb) on arthritis models and its mechanism.
Neuroendocrine-immunological effects of pineal melatonin

Research Candidate Supervision

Biomarkers in Osteoarthritis
Effects of Fatness and Physical Activity During Childhood on Knee Structual Changes After 20 Years
Genetic Epidemiology of Musculoskeletal Disease
Image Processing on Medical Application- Automatic Methods to Calculate the Area of an Articular Cartilage on a Magnetic Resonance Image
MRI Studies in Osteoarthritis
Physical Activity and Musculoskeletal Health
Synovitis Assessed by MRI in Osteoarthritis
The Effects of Vitamin D Supplement on Sex Hormones in Osteoarthritis
Vitamin D Effects on Osteoarthritis (VIDEO) Study