Web Access Research Portal

Researcher: Champion, AC (Dr Alan Champion)

Fields of Research

Medical bacteriology
Respiratory diseases
Medical infection agents (incl. prions)
Microbiology
Epidemiology
Cellular interactions (incl. adhesion, matrix, cell wall)
Infectious diseases
Medical biochemistry - proteins and peptides (incl. medical proteomics)
Medical parasitology

Research Objectives

Clinical health
Human pharmaceutical treatments
Expanding knowledge in the health sciences

Career Best Publications

Research Publications

A clonal strain of Pseudomonas aeruginosa in Tasmanian patients with cystic fibrosis; Annual Scientific Meetings of the Australian & New Zealand Society of Respiratory Science and the Thoracic Society of Australia & New Zealand
A clonal strain of Pseudomonas aeruginosa in Tasmanian patients with cystic fibrosis; Thoracic Society of Australia and New Zealand Annual Scientific Conference
A survey of virulence genes in Pseudomonas aeruginosa; Australian Society for Microbiology National Scientific Meeting
Antimicrobial susceptibility testing of cystic fibrosis and non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa: a comparison of three methods; British Journal of Biomedical Science
Bacterial cyanogenesis occurs in the cystic fibrosis lung; European Respiratory Journal
Biofilm dispersal and exacerbations of cystic fibrosis lung disease; Pediatric Pulmonology
Cystic fibrosis sputum contains high concentrations of cyanide; Thoracic Society of Australia and New Zealand Annual Scientific Meeting
Decreased virulence of cystic fibrosis Pseudomonas aeruginosa in Dictyostelium discoideum; Microbiology and Immunology
Epidemiology of Pseudomonas aeruginosa in a tertiary referral teaching hospital ; Journal of Hospital Infection
Genome diversity of Pseudomonas aeruginosa isolates from Tasmanian Cystic Fibrosis patients; Australian Society for Microbiology National Scientific Meeting
Host response to transmissible Pseudomonas aeruginosa; European Respiratory Journal
Increased airway iron as a potential factor in the persistence of Pseudomonas aeruginosa infection in cystic fibrosis; The European Respiratory Journal
Investigations into the Tasmanian clonal strain of Pseudomonas aeruginosa; AIMS / AACB National Scientific Meeting
Iron chelation inhibits Pseudomonas aeruginosa biofilm formation; 2006 Annual Scientific Meetings of the Thoracic Society of Australia & New Zealand & the Australian & New Zealand Society of Respiratory Science
Molecular epidemiology of Pseudomonas aeruginosa infections in Tasmania; Australian Society for Microbiology National Scientific Meeting
Persistent Pseudomonas aeruginosa lung infection in cystic fibrosis: new insights from the Tasmanian population, Australia; 10th International Congress on Pseudomonas
Poor clinical outcomes associated with a multi-drug resistant clonal strain of Pseudomonas aeruginosa in the Tasmanian cystic fibrosis population; Respirology
Preliminary feasibility and modelling of a liquid matrix Dictyostelium discoideum virulence assay for Pseudomonas aeruginosa; British Journal of Biomedical Science
Prevalence of exoY and exoS genes in clinical and environmental isolates of Pseudomonas aeruginosa; Australian Society for Microbiology National Scientific Meeting
Sputum neutrophils in cystic fibrosis patients display a reduced respiratory burst; Journal of Cystic Fibrosis
Virulence gene distribution in clinical, nosocomial and environmental isolates of Pseudomonas aeruginosa; Journal of Medical Microbiology
Whole cell virulence of clinical and environmental Pseudomonas aeruginosa in a novel Dictyostelium discoideum eukaryotic model; Australian Society for Microbiology

Research Projects

An Amoeba Co-culture Assay Alternative to Mammalian Models of Bacterial Virulence Testing; The MAWA Trust (MAWA)
Clinical research equipment to accelerate research outputs in molecular and genetic studies; Royal Hobart Hospital Research Foundation (RHHRF)
Does the Tasmanian Clonal Strain of Pseudomonas aeruginosa Identified in Cystic Fibrosis Patients Express Glycosylated Group I Pili that Confer a Survival Advantage in the CF Lung Environment?; Royal Hobart Hospital Research Foundation (RHHRF)
Genetic and Proteomic Analysis of Pseudomonas Aeruginosa Isolates from Tasmanian Cystic Fibrosis Patients; Royal Hobart Hospital Research Foundation (RHHRF)
Investigation of Antibiotic Sensitivity & Virulence Factors of the Tasmanian Clonal Strain of Pseudomonas aeuruginosa Isolated from Cystic Fibrosis Patients; Clifford Craig Foundation (CCFoundation)
Targeting Biofilms and Persistent Lung Infection in Cystic Fibrosis to Develop New Therapeutic Interventions; Royal Hobart Hospital Research Foundation (RHHRF)

Research Candidate Supervision

Pseudomonas aeruginosa in Tasmania